Percutaneous transhepatic gallbladder（PTGB）ランデブー法によ り肝内胆管拡張を伴わない悪性胆管狭窄に対して経乳頭的ステント留 置が可能となった２例

症例１は67歳男性。膵頭部癌十二指腸浸潤に伴う十二指腸粘膜浮腫を認めた。症例２は69歳男性。多発性骨髄腫リンパ節転移・乳頭部腫瘍浸潤を認めた。共に主乳頭の同定が困難で内視鏡的ドレナージが行えず、肝内胆管拡張も無いためPTGBDチューブから十二指腸内に挿入したガイドワイヤーをルートとして胆管へアクセスし（ランデブー法）内瘻化した。主乳頭・肝内胆管からの胆道アクセスが困難な症例においてPTGBランデブー法は有用である

Effects of Salinity on Na~+-K~+-ATPase Activity in Gills,and Concentrations of Ions and Hormones in Serum of Juvenile Turbot(Scophthalmus maximus)

采用饲养试验方法,研究了平均体质量为(7.16±0.07)g的大菱鲆(SCOPHTHAlMuS MAXIMuS)幼鱼分别在盐度12、18、24、30和36下饲养60 d后,其鳃nA+-k+-ATPASE活力、血清离子浓度、生长激素(gH)、皮质醇激素(COr)、特定生长率(Sgr)和饲料效率(fCE)的变化。结果表明:幼鱼鳃nA+-k+-ATPASE活力、血清nA+浓度均随盐度的升高而上升,分别在3.48~8.30 u/Mg和169.99~180.00 MMOl/l之间,其中12盐度组最低,36盐度组最高。幼鱼血清中k+和Cl-浓度分别在2.20~3.47 MMOl/l和136.67~142.00 MMOl/l之间,各盐度组之间差异不显著。幼鱼血清中gH和COr浓度分别在0.41~1.66 ng/Ml和35.33~76.41 ng/Ml之间;其中gH在36盐度组最高,12盐度组最低,而COr在12盐度组最高,36盐度组最低。幼鱼Sgr和fCE分别在(1.45~2.00)%/d和1.12%~1.38%之间,与盐度的相关性不显著,两者均为12盐度组最低。由此可见,盐度变化显著影响大菱鲆幼鱼鳃nA+-k+-ATPASE活力、血清nA+浓度和激素含量。本研究对大菱鲆养殖生理生态条件分析具有重要参考意义,研究结果可为大菱鲆养殖的盐度选择提供理论依据。The Na+-K+-ATPase activity in gill,concentrations of ions and hormones in serum,and specific growth rate and feed conversion efficiency of juvenile turbots( Scophthalmus maximus)( body weight of 7.16 ±0.07 g),which have been reared at salinities 12,18,24,30 and 36 for 60 days,were investigated.The results showed that Na+-K+-ATPase activity and Na+concentration were 3.48- 8.30 U /mg and 169.99-180.00 mmol /L,respectively,and their levels increased with the rise of water salinity.The highest values were observed at salinity 36,and lowest ones at salinity 12.The Na+-K+-ATPase activity and Na+concentration inthe fish reared at salinity 12 were significantly lower than those in the control( P 0.05).Growth hormone and cortisol levels were 0.41- 1.66 and35.33- 76.41 ng /ml,respectively.Growth hormone level was the lowest in the fish reared at salinity 12,and the highest at salinity 36,both of which had significant difference compared to that of the control( P 0.05).Specific growth rate and feed conversion efficiency were( 1.45-2.00) % /day and 1.12%- 1.38%,respectively.Although both were the lowest at salinity 12,they were not significantly correlative with salinity.Thus,the results indicate that the changes in salinity could have significant impacts on Na+-K+-ATPase activity in gill,concentrations of Na+,growth hormone and cortisol in serum of juvenile turbots.The results provide important reference for salinity selection in turbot mariculture.现代农业产业技术体系专项资金(No.CARS-50

ダイニキ Dome Fuji ヒョウショウ コア プロジェクト ニ モチイル コウガク ソウイ キロク ソウチ ノ カイハツ

第二期ドームふじ氷床コアプロジェクトの現場解析において,簡便に光学層位を記録するため,専用装置を開発した.この装置は,二次元的な光の散乱強度を氷床コアサンプルの深さ方向に沿って連続的に測定する.我々は,この装置のハードウェアおよび制御ソフトウェアを開発した.この結果,経験のないオペレーターでも容易に測定可能な,自動測定装置が完成した.測定速度は5mm/sを想定しており,この場合,現場処理解析の基本長である1.5mのサンプルを約6分間で測定可能である.この装置は第44次越冬隊が南極ドームふじ観測拠点に搬入し,第45次夏隊から始まる深層コア掘削の現場解析処理に使用される予定である.An optical scanner for stratigraphical study was developed for the Dome Fuji ice core project II. The optical scanner measures two-dimensional light scattering intensities and records optical structures of ice cores. We developed the scanner hardware and control software. The line scanner is controlled by a personal computer and is constructed for automatic measurement. The sliding speed of the scanner is about 5mm per second and, therefore, one ice core sample with a standard length for our sample processes (1.5m long) can be measured within about six minutes. The line scanner was transported to Dome Fuji Station, Antarctica, by the wintering party of the 44th Japanese Antarctic Research Expedition (JARE-44), and will be used for Dome Fuji II ice core measurement by the JARE-45 summer party and successive parties

Attempts to Improve Teaching at Tohoku University Graduate School of Medicine Health Sciences through Evaluation by Students and Faculty Development

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