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    中枢神经系统(CNS)由大量的神经细胞组成,星形胶质细胞是其中分布最广的一类神经胶质细胞,具有营养支持、调节神经递质及影响突触功能等多种生理功能。星形胶质细胞高表达基因-1(AEG-1)是一种原癌基因,对多种CNS肿瘤细胞的增殖、发展及转移有重要影响。本文从AEG-1对CNS肿瘤的诊断、治疗和预后评估方面的作用进行综述,寻找新的标志物用于CNS肿瘤的诊断和治疗

    JUNO Sensitivity on Proton Decay pνˉK+p\to \bar\nu K^+ Searches

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    The Jiangmen Underground Neutrino Observatory (JUNO) is a large liquid scintillator detector designed to explore many topics in fundamental physics. In this paper, the potential on searching for proton decay in pνˉK+p\to \bar\nu K^+ mode with JUNO is investigated.The kaon and its decay particles feature a clear three-fold coincidence signature that results in a high efficiency for identification. Moreover, the excellent energy resolution of JUNO permits to suppress the sizable background caused by other delayed signals. Based on these advantages, the detection efficiency for the proton decay via pνˉK+p\to \bar\nu K^+ is 36.9% with a background level of 0.2 events after 10 years of data taking. The estimated sensitivity based on 200 kton-years exposure is 9.6×10339.6 \times 10^{33} years, competitive with the current best limits on the proton lifetime in this channel

    JUNO sensitivity on proton decay pνK+p → νK^{+} searches

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    JUNO sensitivity on proton decay p → ν K + searches*

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    The Jiangmen Underground Neutrino Observatory (JUNO) is a large liquid scintillator detector designed to explore many topics in fundamental physics. In this study, the potential of searching for proton decay in the pνˉK+ p\to \bar{\nu} K^+ mode with JUNO is investigated. The kaon and its decay particles feature a clear three-fold coincidence signature that results in a high efficiency for identification. Moreover, the excellent energy resolution of JUNO permits suppression of the sizable background caused by other delayed signals. Based on these advantages, the detection efficiency for the proton decay via pνˉK+ p\to \bar{\nu} K^+ is 36.9% ± 4.9% with a background level of 0.2±0.05(syst)±0.2\pm 0.05({\rm syst})\pm 0.2(stat) 0.2({\rm stat}) events after 10 years of data collection. The estimated sensitivity based on 200 kton-years of exposure is 9.6×1033 9.6 \times 10^{33} years, which is competitive with the current best limits on the proton lifetime in this channel and complements the use of different detection technologies
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