Optimization for astaxanthin extraction from Haematococcus pluvialis with ethanol using response surface methodology

采用安全无毒的乙醇为溶剂,研究了超声时间、料液比、搅拌速度等因素对虾青素提取效率的影响。在此基础上,采用响应面设计对以上3个因素的交互关系进行探究。结果表明,3个因素对虾青素提取率的影响顺序为：超声时间〉料液比〉搅拌速度;最佳提取条件为：超声时间20min、料液比1：150、搅拌速度1000 r/min,在此条件下虾青素提取率可达48.42%。Ethanol, an environmentally friendly solvent, was used to extract astaxanthin from Haematococcus pluvialis. The effect of several conditions, including ultrasound time, the ratio of solid to liquid （S/L） and stirring rate, on astaxanthin extraction rate was investigated. Response surface methodology was applied to study the interaction in these factors. The effects of three factors on the extraction of astaxanthin were in order of ultrasound time, S/L, and stirring rate. The optimal astaxanthin extraction rate was 48.42% with 20 min of ultrasound time, 1：150 of S/L, and 1000 r/min of stirring rate.国家自然科学基金项目（41606177）; 福建省高校产学合作项目（2015N5006）; 福建省教育厅中青年教师教育科研项目（JA15406）; 泉州市科技局校地协同创新项目（2016N056

A Novel Method for Preparation of Activated Alumina

[中文文摘]将结晶氯化铝与柠檬酸及淀粉等造孔剂混合,经直接干燥和焙烧制得了一种无定形活性氧化铝,并通过X射线粉末衍射、N2物理吸附及氨程序升温脱附等手段对活性氧化铝样品进行了表征,探讨了各组分对活性氧化铝样品性质所起的作用.与常规的活性氧化铝制备方法相比,这种制法省去了中和、老化、过滤和洗涤等步骤,缩短制备周期且过程容易控制.活性氧化铝具有适宜且可调节的比表面积和孔径分布,作为载体负载镍金属组分制成负载型催化剂后,对乙苯加氢饱和与加氢裂化表现出较高的催化活性.[英文文摘]A novel and simple method was developed to prepare alumina with suitable specific surface area and pore size distribution. First,AlCl3·6H2O and citric acid were heated without water in a water bath at 90 ℃ with stirring until a homogenous solution was obtained.Then starch was added into is solution.After the solution was dried at 110 ℃ and calcined at indicated temperature, activated alumina was obtained.The activated alumina was characterized by N2 adsorption,X-ray diffraction,and NH3 temperature-programmed desorption. Compared with the usual technology , this novel preparation did not include some steps such as aging , filtering , and washing. Moreover , the specific surface area and pore size distribution of the activated alumina could be controlled and modified by changing the preparation parameters. The supported Ni/ Al2O3 catalyst with the activated alumina as support showed higher activity for hydrogenation and hydrocracking of ethylbenzene.国家重点基础研究发展计划(973计,2004CB217805); 福建省“百千万人才工程”项目; 福建省自然科学基金(U0750016)

Reactor model with cross-flow for aromatics catalytic hydrogenation

[中文文摘]提出了一种抗硫中毒的芳烃加氢催化反应器模型,称之为交叉流反应器模型,把反应物料分为两股,其中含有噻吩的乙苯物料采用轴向连续流动方式由反应器进口进入催化剂床层,而氢气由铅直导管直接进入催化剂床层中,然后与乙苯物料混合。在氢气导管出口处形成含硫乙苯浓度低而氢气浓度高的特殊区域,因而硫对催化剂的中毒效应大幅度降低,整体上提高了乙苯加氢饱和反应效率。与传统轴向混合流反应器进行比较,在相同条件下交叉流反应器具有更好的整体加氢反应性能。分别建立了交叉流反应器与传统轴向混合流反应器模型,提出了两种反应器的催化反应转化率方程;利用此转化率方程,对实验数据进行处理,得到动力学参数,模型的计算结果与实验数据相吻合,也验证了在交叉流反应器中,硫的中毒效应明显减弱。[英文摘要]A novel reactor model named cross-flow reactor for aromatics catalytic hydrogenation was proposed.The reactants were divided into two flows:ethylbenzene with thiophene was introduced to the catalyst bed along the axial direction of the columnar reactor,while hydrogen was introduced into catalyst bed through a vertical pipe with openings.Because special areas with high H2 pressure and low H2S pressure were formed near these openings,the poisoning of catalyst by thiophene was substantially decreased,and consequently the reaction of et hylbenzene hydrogenation was improved as compared with the traditional reactor with mixed co-flow. Finally , kinetic models were established for this cross-flow reactor and the traditional reactor1And the conversion equations of these two reactors were given.By using these equations , the experiments data were fitted to obtain kinetics parameters. The calculation results agreed well with the experimental data. It was also demonst rated that sulfur poisoning in cross-flow reactor was weakened.国家重点基础研究发展计划项目(2004CB217805); 福建省“百千万人才工程”支持项目; 福建省自然科学基金项目(U0750016)

EB病毒潜伏膜蛋白1调节EGF受体核移位

EB病毒编码的病毒潜伏膜蛋白 1(LMP1)是重要的致瘤蛋白,一直以来是EB病毒致瘤机制的研究核心.传统的受体学说认为,细胞膜受体作为第一信使,在细胞膜上与其配体结合发挥生物学效应.但近年来,对EGFR家族成员受体核移位在基因表达调控中意义的研究,拓宽了人们对细胞膜受体生物学功能的认识.利用我们建立的Tet-on系统调控LMP1表达的细胞系,采用Western blot和激光共聚焦显微镜等技术证实,LMP1可调控EGFR的核移位,并呈一定的剂量效应.通过GFP与EGFR及不同突变体的融合蛋白在细胞内的表达发现,EGFR的核定位信号在其核移位过程中起着一定的作用,并初步发现LMP1调控EGFR核移位为配体非依赖性

貌合神离：中英文同款广告的符号和眼动分析

通过一系列中英文同款广告，该研究结合符号和眼动技术，指出相似的表象之下，微妙的细节调整如何折射出中西方读者对媒介内容叙述方式的不同偏好，以及处理群己关系的不同价值取向，从而呈现出“貌合神离”的警民、亲子、师生、夫妻、男女等社会关系。本文系国家自然科学基金项目“东西方不同文化思维方式对广告说服的影响：一个自下而上的脉络建构与验证”（项目编号：71372076）的阶段性研究成果

A Novel Method for Preparation of Activated Alumina

A novel and simple method was developed to prepare alumina with suitable specific surface area and pore size distribution. First, AlCl3 center dot 6H(2)O and citric acid were heated without water in a water bath at 90 degrees C with stirring until a homogenous solution was obtained. Then starch was added into is solution. After the solution was dried at 110 degrees C and calcined at indicated temperature, activated alumina was obtained. The activated alumina was characterized by N-2 adsorption, X-ray diffraction, and NH3 temperature-programmed desorption. Compared with the usual technology, this novel preparation did not include some steps such as aging, filtering, and washing. Moreover, the specific surface area and pore size distribution of the activated alumina could be controlled and modified by changing the preparation parameters. The supported Ni/Al2O3 catalyst with the activated alumina as support showed higher activity for hydrogenation and hydrocracking of ethylbenzene

知识经济与管理会计

由厦门大学会计发展研究中心提供的第五届会计与财务问题国际研讨会——当代管理会计新发展论文集中的第四部分：管理会计创新及相关模式5知识经济对我国传统经济模式提出挑战，同时也对传统模式下的管理会计提出挑战，我国现有的管理会计理论与方法体系必须加以创新才能适应其发展。本文从知识经济对管理会计观念、管理会计方法及管理会计内容等方面所带来的变化出发，探讨了知识经济时代管理会计的创新与发展方向

浅谈企业的核心能力及在我国的运用

核心能力是企业在竞争中获得竞争优势的重要保证,在当今社会竞争日益激烈的情况下,企业打造核心能力尤为重要。本文论述了企业核心能力的含义,对核心能力概念局限性进行了分析并就此提出了修正。在此基础上,对我国企业在如今经济环境下构建核心能力的问题进一步作了探讨

塔里木河中游地区柽柳对地下水埋深的生理响应

以塔里木河中游沙吉力克断面和阿其河断面的柽柳为研究对象,结合两断面地下水埋深的动态监测和柽柳叶片可溶性糖、脯氨酸、MDA含量及SOD、POD活性等生理指标的分析测试,研究了不同地下水埋深与柽柳生理变化的关系,以探讨该地区柽柳的抗旱机理与受胁迫程度.研究表明:随着地下水埋深的不断增加,柽柳叶片的可溶性糖含量、脯氨酸含量、MDA含量和SOD活性均显著增加,而POD活性则呈不断下降的趋势,并且柽柳各生理代谢相互协调;地下水埋深与柽柳叶片的可溶性糖、脯氨酸、MDA含量以及SOD活性呈正相关,相关系数分别为0.602*、0.548、0.735**和0.829**,与POD活性呈负相关(r=-0.709**).研究发现,塔里木河中游地区柽柳的生长已受到严重的干旱胁迫,且沙吉力克断面的柽柳所受到的干旱胁迫较重;柽柳在一定范围内能通过调节体内渗透调节物质的含量和保护酶活性来积极响应地下水埋深的变化,以增强植株自身抗旱能力

不同地下水埋深柽柳、芦苇的生理响应

结合塔里木河中游沙吉力克断面、阿其河断面地下水位的动态监测,对柽柳、芦苇叶片的叶绿素、可溶性糖、丙二醛(MDA)、超氧化物歧化酶(SOD)、过氧化物酶(POD)等生理指标进行分析测试。研究表明,随着干旱胁迫加强,柽柳、芦苇的可溶性糖含量,MDA含量,SOD活性呈显著增加,叶绿素含量和POD活性显著减少,显示出植物受到了不同程度的干旱胁迫,并通过调节自身生理代谢过程,以增强抗旱性;柽柳、芦苇叶片各生理指标和地下水埋深存在着密切的相关关系,与可溶性糖含量、MDA含量、SOD活性呈正相关,与叶绿素含量、POD活性呈负相关;地下水位是影响塔里木河流域植物生理特征的的主要环境因子;在相同水分胁迫下,芦苇的生理过程比柽柳强烈,对地下水埋深变化更为敏感