Flight Simulator Model Integration for Supporting Pilot-in-the-Loop Testing in Model-Based Rotorcraft Design

Model-Based Design (MBD) enables iterative design practices and boosts the agility of the air vehicle development programs. Flight simulators are extensively employed in these programs for evaluating the handling qualities of the designed platforms. In order to keep up with the agility provided by the MBD, integration of the air vehicle models in fairly complex flight simulators needs to be addressed. The AVES Software Development Kit (SDK), which is the simulation software suite of DLR Air Vehicle Simulator (AVES), enables tackling the model integration starting from the modeler’s desktop. Additionally, 2Simulate, which is the enabling real-time simulation infrastructure of AVES SDK, provides automated model integration workflow for MATLAB/Simulink models using Simulink Coder code generation facilities. This paper presents the successful employment of AVES SDK and the 2Simulate model integration workflow for addressing integration challenges for Pilot-in-the-Loop Testing in AVES

Ayçiçeği Bitki Artıklarının Organik Tarım Amaçlı Değerlendirilmesi

İnsan beslenmesinde önemli bir yere sahip olan tarımsal ürünlerin yetiştiriciliğinde kullanılan hormon, ilaç, gübre gibi kimyasal girdiler sağlığı olumsuz yönde etkilemektedir. Bu nedenle günümüzde, toprağa ve bitkiye zarar veren kimyasal maddeler yerine bitkilerin ihtiyacı olan ve insan sağlığını olumsuz yönde etkilemeyen organik gübre ve doğal ilaçlama yöntemleri geliştirilmeye çalışılmaktadır. Organik tarım, insanların sağlıklı beslenmesinin yanı sıra toprak verimliliğini artıracak her türlü organik artıkların değerlendirilmesi ve tarımda devamlılığın sağlanması açısından büyük önem arz etmektedir. Özellikle ayçiçeği bitkisinin tüm kısımlarında %63,9 potasyum (K2O), %21,7 azot (N) ve %14,4 fosfor (P2O5) besin elementleri bulunduğundan, ayçiçeği yetiştiriciliği yapılan yerlerde hasat sonrası arazide kalan belirli miktarda sap ve köklerin toprağa karıştırılarak yeşil gübre olarak kullanılması pratikte uygulanabilecek en önemli yöntemlerden biridir. Ayrıca hasat sonrası geriye kalan sap, tabla gibi kısımlar, yakacak olarak değerlendirilirken, yanma sonucu elde edilen ve yüksek oranda potasyum bulunan külleri tarlaya serpilerek organik gübre olarak da değerlendirilebilmektedir. Bu derlemede; özellikle ülkemizde organik madde yönünden fakir olan araziler için bir kenara atılarak heba edilen ve çevre kirliliğine neden olan ayçiçeği hasat artıklarının organik hammadde olarak kullanılması, organik ürün elde edilmesi yönünde çiftçilerin bilinçlendirilmesi ve bu şekilde ülke ekonomisine sağlayabileceği konular ele alınmıştır

What is the role of primary hip hemiarthroplasty over 70 years of age?

AMAÇ: Yetmiş yaş üzeri anstabil intertrokanterik femur kırıklarda (IFK) hemiartroplasti uyguladığımız olguları morbidite açısından değerlendirdik. Günümüzdeki hemiartroplastinin yerini tartışmayı amaçladık. GEREÇ veYÖNTEMLER: Kliniğimizde 1995-2006 yılları arasında hemiartroplasti yöntemi ile tedevi edilen intertrokanterik femur kırıklı hastaların 75'i çalışmaya dahil edildi. Ortalama takip süreleri 44 (20-82) ay idi. Hastaların 43'ü kadın,32'si erkekti. 45 hastanın sağ, 30 hastanın sol kalçası etkilenmişti. Olguların hepsi Harris kalça skorlamasına göre değerlendirildi. BULGULAR: Harris kalça skorlama sistemine göre dört hastada mükemmel sonuç, 54 hastada iyi sonuç, dokuz hastada orta, sekiz hastada kötü sonuç saptandı.Yetmiş yaş üzeri anstabil IFK'larında uygulanan hemiartroplasti olgularının %78'inde iyi-mükemmel sonuca ulaşılmış olduğu saptandı SONUÇ: Ameliyat süresinin çok kısa olması, skopi gibi teknik donanıma sahip olma şartının olmaması ve erken tam yük verebilme gibi avantajları olan hemiartroplasti yönteminin yaşlı IFK olgularında halen geçerliliğini ve etkinliğini koruyan bir yöntem olduğu sonucuna vardık.OBJECTIVE: We assessed importance of primary hip hemiarthroplasty in treatment algorithm. And we have evaluated patients treated with primary hip hemiarthroplasty for unstable intertrochanteric hip fractures according to morbidity rates. MATERIAL and METHODS: In our clinic between 1995 and 2006; we selected 75 patients treated with primary hip hemiarthroplasty for intertrochanteric femur fracture (IFF). Mean follow-up was 44 months (20-82). Genders of patients were female 43% and male 32%. Numbers of affected hips were 45 right and 30 left. Patients were evaluated with Harris Hip Score. RESULTS: Harris Hip Score of patients; Excellent 4, Good 54, Fair 9 and Poor 8 results were obtained. Seventyeight percent excellent to good results obtained primary hip hemiarthroplasty for unstable intertrochanteric femur fracture patients over 70 years of age. CONCLUSION: There are advantages of primary hip hemiarthroplasty over osteosynthesis for patient's population over 70 years of age such as; short surgery time, no radiation exposure and immediate weight bearing. Primary hip hemiarthroplasty can be an alternative treatment for unstable intertrochanteric fractures in elderly patients so as to achieve earlier mobilization. It is also current and effective treatment option for most elderly

CD11b Expression in Acute Myeloid Leukemia is Associated With Hemostatic Complications and Response to Treatment

Aim:In our study, we aimed to investigate the effects of CD11b expression on myeloblasts on clinical course and prognosis in patients with AML.Materials and Methods:Data of 123 patients diagnosed with AML between 2014-2017 in Trakya University Faculty of Medicine, Department of Hematology, a tertiary referral hospital in the Trakya Region, were evaluated in a retrospective manner. The diagnosis of AML was based on WHO 2016 criteria of Myeloid Neoplasms.Results:Of the 123 patients in our study, 60 were female, and 63 were male. The mean age was 57.93 years. CD11b positivity was observed in 40 patients. Platelet counts were significantly lower in patients with CD11b positivity (p = 0.004). Likewise, D-dimer levels at presentation were higher in the CD11b positive patient group (p = 0.000). Regarding outcomes, patients with CD11b positivity were found to have lower rates of remission with first-line remission induction therapy (p = 0.003). There was no significant relationship between CD11b positivity and overall survival with Kaplan Meier survival analysis (8.5 months in CD 11b positive group, 12.1 months in negative group, p: 0.436).Conclusion:Our study demonstrated that patients with CD11b expression had lower remission rates with remission induction chemotherapy

The frequency of Duchenne muscular dystrophy/Becker muscular dystrophy and Pompe disease in children with isolated transaminase elevation: results from the observational VICTORIA study

IntroductionElevated transaminases and/or creatine phosphokinase can indicate underlying muscle disease. Therefore, this study aims to determine the frequency of Duchenne muscular dystrophy/Becker muscular dystrophy (DMD/BMD) in male children and Pompe disease (PD) in male and female children with isolated hypertransaminasemia.MethodsThis multi-center, prospective study enrolled patients aged 3–216 months with serum alanine transaminase (ALT) and/or aspartate transaminase (AST) levels >2× the upper limit of normal (ULN) for ≥3 months. Patients with a known history of liver or muscle disease or physical examination findings suggestive of liver disease were excluded. Patients were screened for creatinine phosphokinase (CPK) levels, and molecular genetic tests for DMD/BMD in male patients and enzyme analysis for PD in male and female patients with elevated CPK levels were performed. Genetic analyses confirmed PD. Demographic, clinical, and laboratory characteristics of the patients were analyzed.ResultsOverall, 589 patients [66.8% male, mean age of 63.4 months (standard deviation: 60.5)] were included. In total, 251 patients (188 male and 63 female) had CPK levels above the ULN. Of the patients assessed, 47% (85/182) of male patients were diagnosed with DMD/BMD and 1% (3/228) of male and female patients were diagnosed with PD. The median ALT, AST, and CPK levels were statistically significantly higher, and the questioned neurological symptoms and previously unnoticed examination findings were more common in DMD/BMD patients than those without DMD/BMD or PD (p < 0.001).DiscussionQuestioning neurological symptoms, conducting a complete physical examination, and testing for CPK levels in patients with isolated hypertransaminasemia will prevent costly and time-consuming investigations for liver diseases and will lead to the diagnosis of occult neuromuscular diseases. Trial RegistrationClinicaltrials.gov NCT04120168

Podnikatelský plán pro SuperMop

The aim of my bachelor thesis is to write a business plan for a Mobile application for household services. The purpose of the plan is to examine the marketplace of this business and to create and determine the marketing strategies of development that will promote the product and services of the company and be competitive in the Czech market, as well as in the Global market.The analysis of the business plan will include a layout of the administrative plan, along with a SWOT and PEST analysis. I will examine the attractiveness of SuperMop in the marketplace. I will be also using a Porter Five analysis. Five Forces analysis will outline the strategies of the SuperMop marketplace. For marketing, the Marketing Mix plan is being used. This includes Product, Price, Place, and Promotion. Finally, the Financial plan will outline the all the possible costs and the cash flow statement.Cílem mé bakalářské práce je vytvoření podnikatelského plánu pro mobilní aplikaci nabízející služby pro domáctnost. Účelem plánu je analyzovat trh na kterém se toto odvětví pohybuje a vytvořit strategii pro marketing, který bude adekvátně zastupovat zmíněný produkt a bude zároveň konkurenceschopný na českém i světovém trhu. Analýza podnikatelského plánu zahrunuje administrativní plán, společně s rozborem SWOT a PEST. Nadále zkoumám atraktivitu SuperMop aplikace na trhu a užívám Porter Five analýzy, která nastíní obchodní strategii. Pro potřeby marketingu využívám Marketing Mix. Ten zahrnuje produkt (product), cenu (price), místo (place) a propagaci (promotion). Závěrem zhodnotím náklady a tok peněz (cash flow) za použití finančního plánu

Yeni Medya Çağı'nın siyasi söyleminde risk algısı

Bu çalışmada yeni medya araçlarıyla Türk siyasetindeki risk içerikleri incelenmiştir. Günümüz toplumu hızlı bir değişim içindedir. Bu toplumun en belirgin özelliği, bilgi, bilişim ve iletişim teknolojilerinin gelişimi ve buna bağlı olarak sosyal düzende yaşanan keskin dönüşümlerdir. Yeni Medya Çağı olarak adlandırılabilecek bu düzende internet ve sosyal medya ile iletişim sistemi kökten değişmiştir. Değişime, siyaset de eşlik etmiştir. Bu süreçte teknolojinin bir sonucu olarak yeni risk alanları oluşmuştur. Risk hayatın her alanında olduğu için siyaset, yeni medya aracılığıyla risk tabanlı bir söylem oluşturmuştur. Bu nedenle Yeni Medya Çağı'nın siyasi söyleminde risk algısı araştırılmıştır. Araştırmada Ulrich Beck'in Risk Toplumu ve MichelFoucault'nun iktidar çözümlemelerinin günümüz dünyasını en iyi şekilde yansıttığı düşünülmüştür. Bu çerçevede siyasette en çok kullanılan sosyal medya aracı olan Twitter araştırmaya konu edilmiştir. Türk siyasetini temsil eden 4 liderin Twitter hesapları, 31 Mart 2019 Yerel Seçimleri döneminde incelenmiş, ek olarak veri elde edebilmek için 4 partinin İzmir İl Başkanları ve delegeleriyle derinlemesine görüşme yapılmıştır. Niteliksel olan bu çalışma ile seçim döneminde Twitter kullanım analizi, Türk siyasi haritası, siyasette riskin konumu ve siyasi alanın yeni medya araçlarıyla siyasi sunum yapma pratikleri çözümlenmiştir.In this study, Risk content in Turkish politics was examined with new media tools. Today's society is changing rapidly. The most distinctive feature of this society is the development of information, information and communication technologies and, accordingly, the sharp transformations in the social order. In this order, which can be called the New Media Age, the system of communication with the internet and social media has changed radically. Change has been accompanied by politics. As a result of this process, new areas of risk have been created due to technology. Because risks have a place to be in all aspects of life, politics has created a risk-based discourse through new media. For this reason, the perception of risk has been investigated in the political discourse of the new media age. In the study, Ulrich Beck's Risk Society and Michel Foucault's analysis of power were considered to best reflect the modern world. Against this background, Twitter, the most widely used social media tool in politics, has been the subject of research. The Twitter accounts of 4 leaders representing Turkish politics were examined during the 31 March 2019 local elections, and in addition, in-depth interviews were conducted with the Izmir provincial presidents and delegates of 4 parties to obtain data. The qualitative analysis of Twitter usage during the election period, the Turkish political map, the position of risk in politics and the practice of making political presentations with New Media tools of the political field were analyzed

Blockchain

The recent emergence of blockchain technology is being seen as an important tool in the digital revolution of the health care industry, and several research studies have identified the potential of blockchain technology in the health care industry. It is on the brink of transforming the way traditional medical systems and businesses deal with the health sector and relating agencies. Blockchain, along with Information and Communication Technologies are key technologies for the decentralization and digitization of health care institutions which provide modern and digital health ecosystems for patients as well as service providers. Blockchain applications for health care data management create tools for patients, doctors, and health care institutions in line with control and access to patient’s records, claims, management of payments, management of medical IoT security, research data validations, and financial control and changes in transparency. In these applications, real-time updates are made to an encrypted, decentralized blockchain notebook to understand, monitor, and control medical information. This also makes it easier for health care institutions to restrict unauthorized access to sensitive information. on this thesis application of blockchain technology benefits in healthcare will be outlined.The recent emergence of blockchain technology is being seen as an important tool in the digital revolution of the health care industry, and several research studies have identified the potential of blockchain technology in the health care industry. It is on the brink of transforming the way traditional medical systems and businesses deal with the health sector and relating agencies. Blockchain, along with Information and Communication Technologies are key technologies for the decentralization and digitization of health care institutions which provide modern and digital health ecosystems for patients as well as service providers. Blockchain applications for health care data management create tools for patients, doctors, and health care institutions in line with control and access to patient’s records, claims, management of payments, management of medical IoT security, research data validations, and financial control and changes in transparency. In these applications, real-time updates are made to an encrypted, decentralized blockchain notebook to understand, monitor, and control medical information. This also makes it easier for health care institutions to restrict unauthorized access to sensitive information. on this thesis application of blockchain technology benefits in healthcare will be outlined

Examination of Consumers Purchasing Behavior on the Mother' s Day in the Context of Theory of Reasoned Action

Tüketiciler, tüketim teşvikleriyle beraber günümüzde önemi artan özel günlerde (Yılbaşı, Anneler, Babalar, Sevgililer Günü vb.) daha fazla hediyeleşme davranışını sergilemektedirler. Bu çalışmanın amacı, tüketicilerin özel günlerde hediyeleşme davranışını nasıl değerlendirdikleri ve anneler günü hediye satın alma davranışlarının incelenmesidir. Bu bağlamda sosyal bilimlerde insan davranışlarını incelemek için kullanılan yöntemlerden biri olan Sebepli Davranış Teorisi (SDT) çerçevesinde çalışma yürütülmüştür. Tüketicilerin hediye satın alma davranışına yönelik tutumları ile öznel normlarının (çevresindeki insanlar tarafından oluşturulan sosyal baskılar) kişinin niyeti ve fiili davranışları üzerindeki etkileri araştırılmıştır. Bu doğrultuda Recep Tayyip Erdoğan Üniversitesinde eğitim gören öğrenciler ana kütle olarak ele alınmış ve 285 öğrenciye çevrimiçi anket uygulanmıştır. Elde edilen veriler üzerinde tanımlayıcı istatistikler, açıklayıcı ve doğrulayıcı faktör analizi ile güvenirlilik analizleri yapılarak yapısal model test edilmiştir. Model sonuçları incelendiğinde, tutumun niyet üzerinde anlamlı bir etkisi olduğu, öznel normun ise niyet üzerinde hiçbir etkisi olmadığı görülmüştür. Sonuç olarak anneler gününde hediye satın alma davranışının gerçekleşmesinde tutum tarafından önemli ölçüde etkilenen niyetler, davranışların önemli bir belirleyicisi olmuştur.Together with consumption incentives, consumers are exhibiting more gift-giving behaviors in special occasions (Christmas, Mother's Day, Father's Day and Valentine's Day, etc.), which are increasing in importance today. The purpose of this study is to examine how consumers perceive the gift-giving behavior on special occasions and the behavior of purchasing gifts on their mother's day. In this context, a study has been carried out within the framework of the Theory of Reasoned Action (TRA), one of the methods used to examine human behavior in social sciences. The effects of consumers attitudes and subjective norms to gift buying behavior on one's intentions and actual behavior were investigated. In this respect, the students who were educated at Recep Tayyip Erdoğan University were considered as the main body and 285 students were applied online questionnaire. Structural model was tested by using descriptive statistics, explanatory and confirmatory factor analysis and reliability analysis on the obtained data. When the model results were examined, it was seen that the attitude had a significant effect on the intention while the subjective norm had no effect on the intention. As a result, intentions that are significantly influenced by attitude in the realization of gift buying behaviors on the mother's day have become an important determinant of their behavior