Phosphorus and humic acid application alleviate salinity stress of pepper seedling

Humic acid is a commercial product that contains many elements which improve the soil fertility and increase the availability of nutrient elements. It consequently affects plant growth and yield and ameliorates the deleterious effects of salt stress. The objective of the study was to determine the effect of humic acids and phosphorus on growth and nutrient content of pepper seedlings (cv. Demre) grown under moderate salt stress in growth chamber conditions. Applications of different levels of phosphorus [0 (P0), 50 (P1), 100 (P2) and 150 (P3) mg kg-1] and humic acid [0 (HA0), 750 (HA1) and 1500 (HA2) mg kg-1] to growing media containing moderate salt dose (8 mM NaCl treatment) were studied. The study was replicated four times with 20 plants in each replicate. Humic acid (HA) and phosphorus applications increased the growth and growth parameter of plants. In company, effects of HA and P application was more effective on growth and growth parameter than each separate effect. The optimum total yield was obtained from 69 mg kg-1 P application with HA2 doses according to regression analysis. Humic acid application significantly increased N, P, K, Ca, Mg, S, Mn and Cu contents of shoot of pepper seedling. Also, N, P, K, Ca, S, Fe, Mn, Zn and Cu contents of root were increased with humic acid application. Na contents of both shoot and root of pepper decreased with increased humic acid doses. It can be concluded that high humic acid doses has positive effects on salt tolerance based on the plant growth parameters and nutrient contents. The present study suggests that HA treatments can ameliorate the deleterious effects of salt stress on pepper plants and HA could offer an economical and simple application to reduce problems of pepper production in moderately saline soil.Keywords: Nutrient uptake, plant growth parameter, salt stress, pepperAfrican Journal of Biotechnology Vol. 9(36), pp. 5845-5851, 6 September, 201

Masthead

PubMed: 31444906Aims: Periodontal diseases negatively affect implant osseointegration. Perturbations in non-neuronal cholinergic signalling mechanisms are associated with periodontitis; however, their role in generalized aggressive periodontitis (GAgP) is unknown. The aim of this prospective case–control study was to determine the relationship between non-neuronal cholinergic signalling mechanisms, secreted Ly-6/uPAR-related protein-1 (SLURP-1), interleukin-17 (IL-17) family cytokines and healing of dental implants in health and GAgP. Material and Methods: Thirteen GAgP patients and seven periodontally healthy individuals (PH) were recruited. Peri-implant crevicular fluid (PICF) was obtained at baseline and 1 month post-placement. Acetylcholine (ACh) levels and cholinesterase activity were determined biochemically. SLURP-1, IL-17A and IL-17E levels were determined by ELISA. Marginal bone loss (MBL) at 1 and 6 months post-placement was determined radiographically. Results: The concentration of ACh, cholinesterase activity and IL-17A levels was elevated in PICF of patients with GAgP compared to PH individuals at baseline and 1 month post-placement. The concentration of ACh and cholinesterase activity levels in PICF correlated with levels of IL-17A and MBL around implants 1 month post-placement in patients with GAgP. Conclusions: Non-neuronal cholinergic mechanisms may play a role in the aetiopathogenesis of GAgP and may directly or indirectly, through modulation of IL-17A, influence early implant osseointegration and potential long-term implant survival. © 2019 John Wiley & Sons A/S. Published by John Wiley & Sons Lt

Granüloza hücreli over tümörlerinin yönetimi: Tersiyer bir merkeze ait 10 yıllık deneyim

Objective: Granulosa cell tumors (GCT) arise from the mesenchymal cells and sex cords of the ovaries and can be observed in women of all age groups. This study presented our 10 year-long gynecology oncology experience on the clinical course and outcome of GCT cases. Methods: Thirty-one patients who were operated due to suspicious adnexal masses in our hospital between January 2011 and January 2018 and whose final pathology report confirmed the diagnosis of GCT was included in the study. The data of the patients were evaluated. Preoperative ultrasound findings and serum tumor marker results are noted. Results: Twenty-nine (94%) patients were diagnosed with AGCS and only two (6%) patients were diagnosed with JGCS. The mean age of the study population was 47.74 14.47 years and the mean body mass index was 32.51 7.1. Most patients presented with heavy menstrual bleeding (29%). 48.4% of the patients underwent hysterectomy with bilateral salpingo-oophorectomy, and complete lymph-node dissection, whereas 22.6% of them had hysterectomy with bilateral salpingo-oophorectomy, and 29% of them had oophorectomy only. Three patients (9.3%) had a disease recurrence. The overall survival was 54.4 29.3 months and disease free survival was 49.6 24.2 months. Conclusion: The most important predictor of survival among patients with GCT is a disease stage at the time of initial diagnosis. Long-term surveillance, including routine clinical follow-up and evaluation of tumor markers is mandatory.Amaç: Granüloza hücreli tümörler (GCT) yumurtalıkların mezenkimal hücrelerinden ve cinsiyet kordonlarından ortaya çıkar ve her yaş grubundaki kadınlarda görülebilir. Bu çalışma, GCT olgularının klinik seyri ve sonuçları hakkında 10 yıllık jinekoloji onkoloji deneyimimizi sunmayı amaçladı. Yöntem: Ocak 2011-Ocak 2018 tarihleri arasında hastanemizde şüpheli adneksiyal kitle nedeniyle ameliyat edilen ve son patoloji raporu GHT tanısı ile doğrulanan 31 hasta çalışmaya dahil edildi. Hastaların verileri değerlendirildi. Preoperatif ultrason bulguları ve serum tümör belirteç sonuçları not edildi. Bulgular: Yirmi dokuz (%94) hastaya AGCS tanısı kondu ve sadece iki (%6) hastaya JGCS tanısı kondu. Çalışma popülasyonunun ortalama yaşı 47,74 14,47 yıl ve ortalama vücut kitle indeksi: 32,51 7,1 idi. Hastaların çoğu ağır adet kanaması (%29) ile başvurdu. Hastaların %48,4’üne bilateral salpingo-ooferektomi ve tam lenf nodu diseksiyonu ile histerektomi, %22,6’sına bilateral salpingo-ooferektomi ile histerektomi, %29’una sadece ooferektomi yapıldı. Üç hastada (%9,3) hastalık nüksü vardı. Genel sağkalım 54,4 29,3 aydı ve hastalıksız sağkalım 49,6 24,2 aydı. Sonuç: GCT’li hastalar arasında sağkalımın en önemli prediktörü, ilk tanı anındaki hastalık evresidir. Tümör belirteçlerinin rutin klinik takibi ve değerlendirmesini içeren uzun vadeli sürveyans zorunludur

Robust, Long-Term Culture of Endoderm-Derived Hepatic Organoids for Disease Modeling

Organoid technologies have become a powerful emerging tool to model liver diseases, for drug screening, and for personalized treatments. These applications are, however, limited in their capacity to generate functional hepatocytes in a reproducible and efficient manner. Here, we generated and characterized the hepatic organoid (eHEPO) culture system using human induced pluripotent stem cell (iPSC)-derived EpCAM-positive endodermal cells as an intermediate. eHEPOs can be produced within 2 weeks and expanded long term (>16 months) without any loss of differentiation capacity to mature hepatocytes. Starting from patient-specific iPSCs, we modeled citrullinemia type 1, a urea cycle disorder caused by mutations in the argininosuccinate synthetase (ASS1) enzyme. The disease-related ammonia accumulation phenotype in eHEPOs could be reversed by the overexpression of the wild-type ASS1 gene, which also indicated that this model is amenable to genetic manipulation. Thus, eHEPOs are excellent unlimited cell sources to generate functional hepatic organoids in a fast and efficient manner

Recent Advances in Health Biotechnology During Pandemic

The outbreak of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which emerged in 2019, cut the epoch that will make profound fluctuates in the history of the world in social, economic, and scientific fields. Urgent needs in public health have brought with them innovative approaches, including diagnosis, prevention, and treatment. To exceed the coronavirus disease 2019 (COVID-19) pandemic, various scientific authorities in the world have procreated advances in real time polymerase chain reaction (RT-PCR) based diagnostic tests, rapid diagnostic kits, the development of vaccines for immunization, and the purposing pharmaceuticals for treatment. Diagnosis, treatment, and immunization approaches put for- ward by scientific communities are cross-fed from the accrued knowledge of multidisciplinary sciences in health biotechnology. So much so that the pandemic, urgently prioritized in the world, is not only viral infections but also has been the pulsion in the development of novel approaches in many fields such as diagnosis, treatment, translational medicine, virology, mi- crobiology, immunology, functional nano- and bio-materials, bioinformatics, molecular biol- ogy, genetics, tissue engineering, biomedical devices, and artificial intelligence technologies. In this review, the effects of the COVID-19 pandemic on the development of various scientific areas of health biotechnology are discussed

DETERMINATION OF PHYSICOCHEMICAL AND MICROBIOLOGICAL PROPERTIES OF SOME SALAD DRESSING

Bu çalışmada piyasada satışa sunulan salata soslarının fizikokimyasal ve mikrobiyolojik özelliklerinin belirlenmesi ve bu salata soslarının kalite özelliklerinin araştırılması amaçlanmıştır. Bu çalışma için, 4 farklı markadan 14 adet salata sosu piyasadaki satış noktalarından temin edilmiştir. Temin edilen örneklerde akış davranış reolojik özelliklerine formülasyonunun etkisi araştırılmıştır. Örneklerin K ve ?0 değerleri sırasıyla, 0,8000 – 23,5000 (Pa.s)n ve 0,2000 – 37,0000 (Pa) olarak bulunmuş ve bu değerler arasında büyük farklar gözlemlenmiştir. Salata soslarının fizikokimyasal özelliklerini belirlemek için % asitlik ve L*, a*, b* renk analizleri yapılmıştır. Analizler sonucunda salata soslarının içerdikleri farklı bileşenlerin fizikokimyasal özelliklerini belirlemede ne kadar önemli olduğu anlaşılmıştır. Renk analizinde ise özellikle a* değerine etki eden kırmızı biber, kırmızı biber püresi, domates püresi vb. bileşenler olduğu tespit edilmiştir. Salata soslarında mikrobiyal gelişimi gözlemlemek amacıyla maya ve küf sayımı yapılmıştır. Örneklerde maya ve küf sayıları tespit edilebilir limitlerin altında belirlenmiştir. Bu çalışmadan elde edilen sonuçların salata sosu kullanan tüketiciler ve salata sosu üretimi yapan piyasa için yol gösterici bir kaynak olması hedeflenmektedirIn this study, it was aimed to determine the physicochemical and microbiological properties of the salad dressings on the market and to investigate the quality characteristics of these dressings. For this study, 14 salad dressings from 4 different brands were obtained from local markets. The effect of the formulation on the rheological properties of the samples was investigated. The K and ?0 values of the samples were found to be 0,8000 – 23,5000 (Pa.s)n and 0,2000 – 37,0000 (Pa), respectively and significant differences were observed between these values. % acidity and L *, a *, b * color parameters were analyzed to determine the physicochemical properties of salad dressings. As a result of the analyzes, it was understood that specific ingredients in the formulation of the salad dressings were important in determining their physicochemical properties. In the color analysis, especially for a*, red pepper, red pepper puree, tomato puree etc. components have been found to be effective. In order to observe microbial growth in salad dressings, yeast and mold counts were performed. Yeast and mold counts were below the detectable limits. The results of this study are intended to be a guiding literature source for consumers who use salad dressing and salad dressing industry that produce salad dressing

Antiviral Kullanımına Bağlı Gelişen Femoral Nöropati: Olgu Sunumu

Femoral sinir lezyonu, kalça fleksiyonu ve diz ekstansiyonunda kuvvetsizlik, patella derin tendon refleksinde azalma, uyluk ve bacak anteromedialinde hipoestezi ile seyreder. İlaç kullanımına bağlı olarak nadir de olsa görülebilmektedir

Create a Country Perception and Image by International Public Relations: An Empirical Research about Perception and Image of Turkey in Germany (2010-2013)

Önder, Hatice Burcu (Arel Author)For centuries, countries have always communicated with each other, such as wars, political and economic power struggles, outbreaks, migrations, border changes, technical developments. This communication is sometimes caused by reasons such as political or economic power struggles. Today, countries have to deal with the developments, trade, social, cultural exchanges that are happening within the borders of each other. It is necessary for one country to have a good place in the international arena. Counties need to gain a positive place in international communication. Providing a positive perception in the international arena will feed countries in commercial, economic and political sense. Positive perception will lead to greater investment in the country, increased cooperation and ultimately achieving country interests at the final point

Create a Country Perception and Image by International Public Relations: An Empirical Research about Perception and Image of Turkey in Germany (2010-2013)

Önder, Hatice Burcu (Arel Author)For centuries, countries have always communicated with each other, such as wars, political and economic power struggles, outbreaks, migrations, border changes, technical developments. This communication is sometimes caused by reasons such as political or economic power struggles. Today, countries have to deal with the developments, trade, social, cultural exchanges that are happening within the borders of each other. It is necessary for one country to have a good place in the international arena. Counties need to gain a positive place in international communication. Providing a positive perception in the international arena will feed countries in commercial, economic and political sense. Positive perception will lead to greater investment in the country, increased cooperation and ultimately achieving country interests at the final point