Effects of different commercial solutions in therapy of hypovolemia in dogs

Hypovolemia is represented in the clinical pathology of the dog in a high percentage. It mostly presents an accompanying syndrome in many diseased conditions (vomiting, diarrhea, sequestration, burns, cold burns, ascites periocardiac efusions, and others), while they primarily occur following acule hemorrhagia. Having in mind its diverse etiology, hypovolemia, in addition to a lack of fluids, can also be characterized by various other deficiencies (of electrolytes, proteins, albumins, carbohydrates), which presents an important factor for evaluating the condition of the patient and prescribing the adequate therapy

Ethnic Stereotypes in the Discourse of Former-Yugoslav TV and Cinema

This paper is an attempt to analyze particular scenes from the TV series “Složna braća” and “Crni Gruja” and the film “Balcancan” for the purpose of surveying the featured stereotypical representations of former-Yugoslav ethnicities, identifying their roles within the said examples of film and TV discourse, and proving that familiarity with the discursive practices of these particular cultures (discourse communities) is essential for interpreting these artistic discourses (texts) in the manner intended by their authors. Ethnic stereotypes are, therefore, discussed as socio-cultural constructs or myths generated by the discursive practices of a particular culture, as, it is discourses that “bring cultural objects into being by naming them, defining them and delimiting their field of operation” (Stam, Burgoyne and Flitterman-Lewis 2005: 216). They are also viewed as part of a larger structure – a discursive universe comprised of interrelated mythical texts (Johansen and Larsen 2002: 55–56) shaped by former-Yugoslav discourse communities. For this reason, the mentioned texts will be analyzed as sharing the said discursive universe

Fuzzy sets (in)equations with a complete codomain lattice

summary:The paper applies some properties of the monotonous operators on the complete lattices to problems of the existence and the construction of the solutions to some fuzzy relational equations, inequations, and their systems, taking a complete lattice for the codomain lattice. The existing solutions are extremal - the least or the greatest, thus we prove some extremal problems related to fuzzy sets (in)equations. Also, some properties of upper-continuous lattices are proved and applied to systems of fuzzy sets (in)equations, in a special case of a meet-continuous complete codomain lattice

Determining Free-Flow Speed on Different Classes of Rural Two-Lane Highways

Current analytical free-flow speed models consider all rural two-lane highways as the same road type despite their different functional significance in the network. The aim of this paper is to develop a prediction model for free-flow speed as a function of speed limit and road geometric characteristics for different classes of rural two-lane highways. The research was conducted on 50 representative sections of the two rural classes of two-lane highways equipped with automatic traffic counters in Serbia. In order to develop the appropriate models, it was necessary to determine the threshold values of vehicle time headway in the free-flow for both classes of rural two-lane highways, based on the total number of 191,720 vehicles. The obtained results show that there are differences in the threshold values of free-flow time headway for different road classes. Namely, it was determined that the values of free-flow time headway for Class I amounted to 6.3 s, and for Class II to 8.4 s. The free-flow speed prediction model for different road classes showed that speed limit had the highest impact on free-flow speed for Class I and II highways, followed by horizontal curve radius and shoulder width

Association between microRNAs and clinical parameters and response to radiotherapy combined with temozolomide in patients with glioblastoma

Cilj: Ciljevi ovog istraživanja bili su da se ispita povezanost mikro RNK-10b/21/34a sa kliničkim parametrima i odgovorom na radioterapiju kombinovanu sa temozolomidom kod bolesnika sa glioblastomom. Materijal i metode: U istraživanje su bila uključena 43 pacijenta sa glioblastomom lečenih po Stupovom protokolu. Istraživan je nivo ekspresije mikro RNK-10b/21/34a u tri vremenske tačke. Analizirane su demografske karakteristike pacijenata, kliničko-prognostički faktori, akutna toksičnost, preživljavanje bez progresije bolesti (PFS), ukupno preživljavanje (OS) i njihova povezanost sa nivoima ekspresije mikro RNK-10b/21/34a. Rezultati: Medijana PFS kod naših pacijenata bila je 10 meseci, a medijana OS bila je 15 meseci. 51.2% pacijenata je imalo akutnu toksičnost. 77.3% pacijenata je toksičnost imalo nakon 30. frakcije RT. Pacijenti sa toksičnošću pretežno su bili distribuirani u grupi pacijenata koji su imali glioblastom, NOS. Viši nivoi ekspresije miR-10b i miR-21 pretežno su povezani sa većim gradusom toksičnosti. Nivoi ekspresije miR-34a bili su značajno povišeni na 15. i 30. frakciji zračne terapije, u odnosu na početne vrednosti. Tumori manji od 4 cm su imali višu ekspresiju miR-10b i miR-21 u tački pre početka RT sa TMZ. Duži PFS utvrđen je za vrednosti ekspresije iznad medijane za miR-21 i miR-34a. Duži OS imali su pacijenti sa vrednostima ekspresije miR-10b iznad medijane. Zaključak: Ovo istraživanje je pokazalo da se mikro RNK-10b/21/34a menjaju tokom hemio-radioterapije i da su povezane sa akutnom toksičnošću. Ovaj koncept je jedinstven i sugeriše da se dinamične promene poput varijacija nivoa ekspresije mikro RNK, mogu koristiti kao parametri za predikciju radiosenzitivnosti, odgovora na RT i predikciju akutne toksičnosti.Aims: The objectives of this research were to investigate the associations between microRNA-10b/21/34a and clinical parameters and response to radiotherapy combined with a temozolomide in patients with glioblastoma. Methods: This study included 43 patients with glioblastoma, treated according to Stupp’s regimen. The levels of expression of microRNA-10b/21/34a were measured in the three-time points, at a baseline, at 15th and 30th fraction of radiotherapy (RT). Demographic characteristics of patients, clinical-prognostic factors, acute toxicity, progression-free survival (PFS), overall survival (OS), and correlation with the levels of expression microRNA-10b/21/34a were analyzed. Results: The median PFS in our cohort was 10 months, and the median OS was 15 months. 51.2% of patients had acute toxicity. 77.3% of the patients with toxicity had toxicity after 30th fraction of radiotherapy. Patients with toxicity were predominantly distributed in the group glioblastoma, NOS subtype. Higher expression levels of microRNA-10b and microRNA-21 are predominantly associated with a higher grade of toxicity. The expression levels of miR-34a were significantly elevated at the 15th and 30th fraction of RT, in comparison to baseline levels. Patients with tumor size less than 4 cm had higher expression levels of miR-10b and miR-21 at the baseline. The longer PFS was noticed in patients with expression values above the median value of microRNA-21 and microRNA-34a. Patients with microRNA-10b expression values higher than the median had better OS. Conclusions: This research showed microRNA-10b/21/34a change over treatment and that they are associated with acute toxicity. This concept is unique and suggests that dynamic changes such as variations of microRNA expression levels can be used as parameters for radiosensitivity, response to RT, and prediction of acute toxicity

The organization of teaching in regular schools and education of students with sensory impairments

У редовним школама настава се заснива на поштовању педагошких принципа, међу којима доминира принцип очигледности, заснован на усвајању знања путем чула вида и слуха. Овим радом настојимо да испитамо начин организовања наставе у случајевима када је неко од ова два чула ученику оштећено, као и могућности да се образовно-васпитни рад прилагоди и оријентише према његовим потребама...In regular schools, teaching is based on respecting принциплес principles od pedagogy, dominated by the principle of obviousness based on the acquisition of knowledge through senses of sight and hearing. This work tries to examine methods for organizing teaching in cases where one of these two pupil’s senses is damaged, as well as the opportunities to adjust and manage educational work according to pupil’s needs..

KAKO SMO PREŽIVJELE POSTKOLONIJALIZAM: Pravo na identitet u dramama fragile! i Nevidljivi Tene Štiviĉić

U ovome se radu tumače dvije drame suvremene hrvatske autorice Tene Štivičić u kontekstu postkolonijalne kritike i hrvatske drame. Uporište mojega tumačenja drama fragile! i Nevidljivi jesu intertekstualne spone Tene Štivičić i suvremenoga hrvatskog dramskog ženskog pisma koje, kako ću nastojati pokazati, ima dugu povijest progovaranja s margine i o margini. Žensko dramsko pismo kritizira i redefinira „univerzalne“ stavove o pojedincu i društvu, jeziku, povijesti, kulturnoj i estetskoj formi (Lada Čale Feldman). Analizirane drame čine isto, pri čemu je središnje mjesto njihovih zapleta i mojega čitanja problem identiteta i alteriteta, sepstva i drugosti. Identiteti su rezultat uspješne artikulacije ili „ulančavanja“ subjekta u tok diskursa (Stuart Hall). Ulančavanje subjekata u fiktivne i/ili teorijske diskurse generira zaplete imigrantskih drama Tene Štivičić. Londonskim su imigrantima ponuĎena dva diskursa – orijentalizam i balkanizam, dvije artikulacije drugosti. Unatoč nastojanjima da se upišu u neoliberalne mitove o samoostvarenju, njihovo je nepripadanje neiskupljivo. U dramama je, osim rasnih, etničkih i vjerskih razlika, vaţno i rodno nepripadanje tematizirano nasiljem nad ţenama, prostitucijom i objektifikacijom – imigrantkinje su dvostruke autsajderice

Aproksimacije funkcionala gustine u proučavanju energija spinskih stanja kompleksa prelaznih metala.

Many fascinating features of coordination chemistry originate from the fact that small changes in metal ion environment can induce big changes in the properties of the compounds. Moreover, most transition-metal (TM) ions with partially filled d-shells can manifest different spin multiplicity in the ground state that is, different spin states. The identity of the ground spin state and the analysis and description of close lying states of different multiplicity is of crucial importance for the understanding of the microscopic origin of the reactivity, electrochemistry and photochemistry in biomolecules, industrial catalysis and in spin crossover compounds. However, elucidating the role and effect of different spin states on the properties of a system, and even determining which spin state occurs naturally, is challenging task both from an experimental and theoretical point-of-view...Mnoge fascinantne osobenosti koordinacione hemije potiču od činjenice da male promene u okruženju centralnog metala mogu izazvati velike promene u svojstvima jedinjenja. Štaviše, većina jona prelaznih metala (TM) sa delimično popunjenim d-orbitalama može manifestovati različit spinski multiplicitet u osnovnom stanju, tj. različita spinska stanja. Identitet osnovnog spinskog stanja i analiza i opis bliskih spinskih stanja različitog multipliciteta su od ključnog značaja za razumevanje mikroskopskog porekla reaktivnosti, elektrohemijskih osobina, fotohemijskog ponašanja biomolekula, industrijske katalize i spin-crossover (SCO) jedinjenja. Međutim, razjašnjavanje uloge i efekta različitih spinskih stanja na osobine sistema, pa čak i samo određivanje osnovnog spinskog stanja je komplikovan zadatak sa eksperimentalne kao i teorijske tačke gledišta..