INTERACTIVE SCHEDULING SYSTEM

This paper deals with the discussion on the use of simulation techniques for work order scheduling on the factory floor level of production and contains a description of the program electronic planning board with simulation elements for Finite Capacity Scheduling. The ability to implement simulation effectively for factory scheduling is dependent upon the availability of shop floor data and the response time for the evaluation process

Circulating sclerostin levels in relation to nutritional status, sex hormones and selected bone turnover biochemical markers levels in peri- and postmenopausal women

Objectives: Hormonal changes during the peri- and postmenopausal age, especially decreasing estradiol levels as the result of the expired ovarian function, are an established link of the pathogenesis of postmenopausal osteoporosis. The objective of the study was to examine the association between the circulating sclerostin levels and nutritional status, sex hormones and selected bone markers turnover levels in peri- and postmenopausal women. Material and methods: The study enrolled 84 stable-body mass women (31 perimenopausal and 54 postmenopausal). Anthropometric measurements and serum estrone, testosterone, androstenedione, DHEA-S, osteocalcin, β-CTx, 25-OHVitamin D and sclerostin levels were obtained. Results: There were not any differences between body mass, BMI, body fat and waist circumference between the study groups. The serum androstenedione and DHEA-S levels were similar in both study groups. However, estrone and total testosterone levels were observed to be notably higher in the perimenopausal group, unlike in the postmenopausal group (124.1 pg/mL vs. 98.3 pg/mL, p < 0.01 and 0.3 pg/mL vs. 0.22 pg/mL, p < 0.01, respectively). Higher plasma osteocalcin and β-CTx levels were shown in the postmenopausal rather than in the perimenopausal group (19.8 ng/mL vs. 16.8 ng/mL, p < 0.001 and 0.35 ng/mL vs. 0.29 ng/mL, p < 0.05, respectively). Plasma sclerostin and 25-OH-Vitamin D levels were similar. There was not any correlation between plasma sclerostin levels and the other studied parameters. In the multivariate regression analyses, sclerostin levels were proportional to the androstenedione ones (b = 0.06; p < 0.05) but inversely related to the log10(testosterone) levels (b = -0.18; p < 0.05). Conclusions: Circulating sclerostin levels are similar in peri- and postmenopausal women and are related to the androstenedione and testosterone levels regardless of the nutritional status

IMPROVING MATERIAL FLOW IN A MODIFIED PRODUCTION SYSTEM

Material flow management aims to ensure the consistency of supply and reliability of the production processes being carried out. The aim of the article is to present a model of material flow organisation in a changing production system operating under small batch production conditions. Carrying out simulations for various production scenarios will be the basis for developing an effective method of material flow management in small batch production of cutting tools

VIRTUAL REALITY IN PRODUCTION LAYOUT DESIGNING

Information technologies allow for improving production systems functioning especially thanks to a possibility of solving complex production problems in a very short time. The production system designing is increasingly based on virtual reality, and more specifically on the concept of a digital factory. It enables to create virtual models of real objects and use them for visualization of products and manufacturing processes. The presented examples of new information technologies, which are used in production practice, are the main object of this paper

Sexuality of disabled athletes depending on the form of locomotion

The main purpose of this study was to determine sexuality of disabled athletes depending on the form of locomotion. The study included 170 disabled athletes, aged between 18 and 45. The entire population was divided into 3 research groups depending on the form of locomotion: moving on wheelchairs (n=52), on crutches (n=29) and unaided (n=89). The research tool was a questionnaire voluntarily and anonymously completed by the respondents of the research groups. The questionnaire was composed of a general part concerning the socio-demographic conditions, medical history, health problems, a part dedicated to physical disability as well as the Polish version of the International Index of Erectile Function (IIEF) and the Female Sexual Function Index (FSFI) evaluating sexual life. STATISTICA 10.0 for Windows was used in the statistical analysis. Subjects moving on crutches were significantly older than ones moving on wheelchairs and unaided (34.41 ±11.00 vs. 30.49 ±10.44 and 27.99 ±10.51 years, respectively) (p=0.018). Clinically significant erectile dysfunctions were most often diagnosed in athletes moving on wheelchairs (70.27%), followed by athletes moving on crutches and moving unaided (60% and 35.42%, respectively; p=0.048). Clinical sexual dysfunctions were diagnosed on a similar level among all female athletes. It was concluded that the form of locomotion may determine sexuality of disabled men. Males on wheelchair revealed the worst sexual functioning. Female athletes moving on wheelchairs, on crutches and moving unaided were comparable in the aspect of their sexual life

Sexual Health of Polish Athletes with Disabilities

The purpose of this study was to determine sexual functioning of Polish athletes with disabilities (including paralympians). The study encompassed 218 people with physical disabilities, aged between 18 and 45 (149 men and 69 women). The entire research population was divided into three groups: Polish paralympians (n = 45), athletes with disabilities (n = 126) and non-athletes with disabilities (n = 47). The quality of sexual life of Polish paralympians was measured by using the Polish version of Female Sexual Function Index and International Index of Erectile Function. Clinically significant erectile dysfunctions were most often diagnosed in non-athletes (83.33%) with 50% result of severe erectile dysfunctions, followed by athletes and paralympians with comparable results of 56.98% and 54.17% respectively (p = 0.00388). Statistically significant clinical sexual dysfunctions concerned lubrication, orgasm as well as pain domains, and prevailed among female non-athletes (68.42%, 68.42% and 57.89%). Practising sports at the highest level has a favourable effect on the sexuality of men and women with physical disabilities. Men with physical disabilities manifest more sexual disorders than women, an aspect which should be considered by health-care professionals working with people with disabilities

Collective administration of copyright and neighbouring and relating rights

Kolektivní správa práv autorských a práv souvisejících s právem autorským Resumé Diplomová práce se zabývá institutem kolektivní správy, důvody jejího vzniku a vývoje až do současného právního stavu. Cílem této práce je popsat práva a povinnosti kolektivních správců vůči ostatním subjektům a kriticky zhodnotit její fungování s ohledem na názory určité části veřejnosti o jejich nadbytečnosti. V práci je rovněž popsán vliv mezinárodního a evropského práva na podobu správců v právním řádu České republiky. Autor se rovněž věnuje judikatuře jak národních soudů, tak i Soudního dvora Evropské unie. Práce je rozčleněna do sedmi kapitol. V prvních dvou kapitolách je nastíněn vývoj kolektivní správy ve světě a na území České republiky. Ve třetí kapitole je popsána účinná právní úprava kolektivní správy. V rámci této kapitoly autor pojednává o jednotlivých kolektivních správcích a právních problémech, se kterými se ten který správce musel vyrovnávat. Dále kapitola popisuje znaky jednotlivých režimů kolektivně spravovaných práv. Na závěr se autor zmiňuje o právech a povinnostech správců vůči nositelům práv, uživatelům práv a státu. V dalších dvou kapitolách jsou rozebrány vlivy mezinárodního a evropského práva na národní právní úpravu. Rovněž je věnován prostor kritické analýze Směrnice o KS, která si klade za cíl...Collective administration of copyright and neighbouring and relating rights Abstract This thesis relates to the collective administration, the reasons for its existence and development to this day. The purpose of my thesis is to describe rights and responsibilities of collecting societies in respect to other relevant legal persons and to evaluate their function with regards to the criticism among public about its abundance. Furthermore, the thesis analyses the influence of the International law and European law on the aspects of collecting societies in the legislation of the Czech Republic. The author also considers the rulings of both national courts, as well as The Court of Justice of the European Union. The thesis is divided into seven chapters. The first two chapters deal with the development of the collective administration in the world and in the Czech Republic. The third chapter is about the effective law regarding collective administration. The author discusses individual collective societies in the Czech Republic. Together with the description, thesis highlights legal issues respective society had to face. Next chapter features the individual regimes of collective administrated rights. The chapter concludes on rights and responsibilities of societies towards the right holders, rights users and the...Institute of Copyright, Industrial Property and Competition LawÚstav práva autorského, práv průmyslových a práva soutěžníhoPrávnická fakultaFaculty of La

Circulating omentin-1 levels and inflammation in polycystic ovary syndrome

Objectives: The aim of the study was to analyze interrelation between plasma omentin-1 levels and nutritional status andinflammation in PCOS.Material and methods: A cross-sectional study involving 86 PCOS (47 obese) and 72 Non-PCOS women (41 obese) determinedanthropometric parameters and body composition. Serum glucose, insulin and omentin-1, TNF-α, sTNFRs, IL-6 andsR-IL6 were measured in the fasting state.Results: Plasma omentin-1 levels were significantly lower in the PCOS than in the Non-PCOS group and both correspondingnormal weight and obese subgroups. In three analyzed least-angle regression (LARS) models the lower plasma omentin-1 levels was associated with PCOS occurrence, higher circulating TNF-α and lower IL-6 levels.Conclusions: Suppressed omentin-1 levels in PCOS are characteristic for this disturbance and proinflammatory cytokinesare factors modifying secretion of this adipokine

Circulating vaspin levels and nutritional status and insulin resistance in polycystic ovary syndrome

Objectives: The study aimed to assess the associations between circulating vaspin levels and nutritional status (assessedon tha basis of BMI) as well as insulin resistance in PCOS.Material and methods: Eighty-seven PCOS women, 48 obese and 39 normal weight, were enrolled in the cross-sectionalstudy. Seventy-two Non-PCOS women, 41 obese and 31 normal weight, constituted a control group. Body mass, height andwaist circumference as well as body composition by bioimpedance were measured. In the morning (16h after the last meal)we determined: serum glucose, insulin, androgens, gonadotropin (LH, FSH) and sex hormone-binding globulin (SHBG) aswell as plasma vaspin levels. Standard HOMA-IR formula was used to assess insulin resistance (IR).Results: Plasma vaspin levels were significantly lower in PCOS, both normal weight and obese, than in Non-PCOSgroups. Vaspin levels were similar in normal weight and obese PCOS subgroups. There was no association between plasmavaspin levels and anthropometric parameters in PCOS group. While in Non-PCOS group a negative correlation betweenplasma vaspin levels and body mass (r = –0.26; p < 0.05) was found. We did not observe correlations between plasma vaspinlevels and serum glucose and insulin concentrations as well as HOMA-IR values, however, in multivariable, stepwise backwardregression waist circumference and HOMA-IR values explained 18.0% of plasma vaspin levels variability in the study subjects.Conclusions: PCOS occurrence is associated with decreased vaspin levels. The influence of nutritional status on vaspin levelobserved in Non-PCOS is abolished in PCOS women, possibly by more severe insulin resistance