112 research outputs found

    Addressing Marijuana Commercialization Amid State-Level Legalization Efforts

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    Several states have acted to defy federal law and legalize the commercialization of marijuana. The resulting conflict between state and federal law represents a constitutional and public health crisis which this paper proposes should be addressed by the United States Government. Efforts to normalize marijuana use and promotion by the new industry have generated widespread use-related concerns, particularly among youth. This paper proposes, analyzes, and recommends a narrowly focused effort by the Departments of Justice and Health and Human Services to begin to address the harms created by state-level commercial marijuana policies

    Brain–computer interfacing with interactive systems-Case study 2

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    info:eu-repo/semantics/publishedVersio

    The role of context in human memory augmentation

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    Technology has always had a direct impact on what humans remember. In the era of smartphones and wearable devices, people easily capture on a daily basis information and videos, which can help them remember past experiences and attained knowledge, or simply evoke memories for reminiscing. The increasing use of such ubiquitous devices and technologies produces a sheer volume of pictures and videos that, in combination with additional contextual information, could potentially significantly improve one’s ability to recall a past experience and prior knowledge. Calendar entries, application use logs, social media posts, and activity logs comprise only a few examples of such potentially memory-supportive additional information. This work explores how such memory-supportive information can be collected, filtered, and eventually utilized, for generating memory cues, fragments of past experience or prior knowledge, purposed for triggering one’s memory recall. In this thesis, we showcase how we leverage modern ubiquitous technologies as a vessel for transferring established psychological methods from the lab into the real world, for significantly and measurably augmenting human memory recall in a diverse set of often challenging contexts. We combine experimental evidence garnered from numerous field and lab studies, with knowledge amassed from an extensive literature review, for substantially informing the design and development of future pervasive memory augmentation systems. Ultimately, this work contributes to the fundamental understanding of human memory and how today’s modern technologies can be actuated for augmenting it

    Non-Invasive Placental Perfusion Imaging in Pregnancies Complicated by Fetal Heart Disease Using Velocity-Selective Arterial Spin Labeled MRI

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    The placenta is a vital organ for fetal growth and development during pregnancy. Congenital heart disease (CHD) is a leading cause of morbidity and mortality in newborns. Despite the parallel development of the placenta and fetal heart early in pregnancy, very few studies suggested an association between placental dysfunction and fetal CHD. In this study, we report placental perfusion of healthy pregnancies and pregnancies complicated by fetal CHD measured using advanced fetal MRI techniques. We studied forty-eight pregnant women (31 healthy volunteers and 17 with fetal CHD) that underwent fetal MRI during their second or third trimester of pregnancy. Placental perfusion imaging was performed using velocity-selective arterial spin labeling (VSASL) and 3D image acquisition with whole-placenta coverage. In pregnancies with fetal CHD, global placental perfusion significantly decreased and regional variation of placental perfusion significantly increased with advancing gestational age; however, no such correlation was found in healthy pregnancies. Also, global placental perfusion was significantly higher in fetal CHD versus controls, in the lateral side-lying patient position versus supine, and in the posterior placental position versus anterior placental position. This study reports for the first time non-invasive whole-placenta perfusion imaging in utero. These data suggest that placental VSASL may serve as a potential biomarker of placental dysfunction in fetuses diagnosed with CHD

    An Integrated Approach to Diabetes Prevention: Anthropology, Public Health, and Community Engagement

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    Diabetes is an enormous public health problem with particular concern within Hispanic communities and among individuals with low wealth. However, attempts to expand the public health paradigm to include social determinants of health rarely include analysis of social and contextual factors considered outside the purview of health research. As a result, conceptualization of the dynamics of diabetes health disparities remains shallow. We argue that using a holistic anthropological lens has the potential to offer insights regarding the nature of the interface between broader social determinants, health outcomes and health disparity. In a primarily Hispanic, immigrant community in Albuquerque, New Mexico, we conducted a mixed methods study that integrates an anthropological lens with a community engaged research design. Our data from focus groups, interviews, a survey and blood sampling demonstrate the need to conceptualize social determinants more broadly, more affectively and more dynamically than often considered. These results highlight a need to include, in addition to individual - level factors that are traditionally the focus of public health and more innovative structural factors that are currently in vogue, an in - depth, qualitative exploration of local context, social environment, and culture, and their interactions and intersectionality, as key factors when considering how to achieve change. The discussion presented here offers a model for culturally situated and contextually relevant scientific research. This model achieves the objectives and goals of both public health and anthropology while providing valuable insights and mechanisms for addressing health disparity such as that which exists in relation to diabetes among Hispanic immigrants in New Mexico. Such an approach has implications for how research projects are designed and conceptualizing social determinants more broadly. The discussion presented provides insights with relevance for both disciplines

    Hydroxychloroquine Use in the United States and the Potential Impact of Critical Shortages from SARS-CoV-2

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    Hydroxychloroquine (HCQ) is in critical shortage in the U.S. because of its use off-label for treatment of viral pneumonia secondary to the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The authors argue critical drug shortages related to off-label use for SARS-COV-2 infection could impact hundreds of thousands of individuals who use the medication for rheumatological diseases.https://deepblue.lib.umich.edu/bitstream/2027.42/154736/1/Niforatos2_hydroxy_covid19_final_4.8.2020.pdfDescription of Niforatos2_hydroxy_covid19_final_4.8.2020.pdf : Main Articl

    Health Disparity and Structural Violence: How Fear Undermines Health Among Immigrants at Risk for Diabetes

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    Diabetes is a national health problem, and the burden of the disease and its consequences particularly affect Hispanics. While social determinants of health models have improved our conceptualization of how certain contexts and environments influence an individual\u27s ability to make healthy choices, a structural violence framework transcends traditional uni-dimensional analysis. Thus, a structural violence approach is capable of revealing dynamics of social practices that operate across multiple dimensions of people’s lives in ways that may not immediately appear related to health. Working with a Hispanic immigrant community in Albuquerque, New Mexico, we demonstrate how structural forces simultaneously directly inhibit access to appropriate healthcare services and create fear among immigrants, acting to further undermine health and nurture disparity. Although fear is not normally directly associated with diabetes health outcomes, in the community where we conducted this study participant narratives discussed fear and health as interconnected
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