Euthanasia as a Caregiving Fantasy in the Era of the New Longevity

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Boomers: From Adorable Baby Bulge to #BoomerRemover

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Decreased pulmonary vascular responsiveness in rats raised on an essential fatty acid deficient diet

Leukotriene C4 is produced during hypoxic pulmonary vasoconstriction and leukotriene inhibitors preferentially inhibit the hypoxic pressor response in rats. If lipoxygenase products are important in hypoxic vasoconstriction, then an animal deficient in arachidonic acid should have a blunted hypoxic pressor response. We investigated if vascular responsiveness was decreased in vascular rings and isolated perfused lungs from rats raised on an essential fatty acid deficient diet (EFAD) compared to rats raised on a normal diet. Rats raised on the EFAD diet had decreased esterified plasma arachidonic acid and increased 5-, 8-, 11- eicosatrieonic acid compared to rats raised on the normal diet (control). Compared to the time matched responses in control isolated perfused lungs the pressor responses to angiotensin II and alveolar hypoxia were blunted in lungs from the arachidonate deficient rats. This decreased pulmonary vascular responsiveness was not affected by the addition of indomethacin or arachidonic acid to the lung perfusate. Similarly, the pulmonary artery rings from arichidonate deficient rats demonstrated decreased reactivity to norepinephrine compared to rings from control rats. In contrast, the tension increases to norepinephrine were greater in aortic rings from the arachidonate deficient rats compared to control. Stimulated lung tissue from the arachidonate deficient animals produced less slow reacting substance and platelet activating factor like material but the same amount of 6-keto-PGF1[alpha] and TXB2 compared to control lungs. Thus there is an associated between altered vascular responsiveness and impairment of stimulated production of slow reacting substance and platelet activating factor like materiali rat raised on an EFAD diet.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/26826/1/0000385.pd

Boomers

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In My Nicaraguan High School: Giving Excluded Women and Men a Second Chance

When I went to Nicaragua for the first time during the Contra war, I had no idea that I would soon wind up helping a Nica friend start two literacy programs and then a Free High School for Adults. It opened in 2002, and now, only 15 years later, we have 1001 graduates, 54% women, 45% rural (mainly from subsistence farm families)--all of them excluded from the regular high schools for one reason or another: being pregnant, being a woman, turning eighteen,  working five days a week, or living too far from town without the ability to pay  bus fare. My real education came with theirs and is still going on, with no end in sight. What I wanted to know was how the teachers--all college graduates who were teaching in the high prestige regular high schools--figured out how to teach these people, many of whom had been out of school for decades and were unused to learning or scholastic discipline; many accustomed to being heads of households; some pregnant or carrying a baby to School for lack of child care or need to nurse; some drunk or exhausted early on Saturday mornings when classes began. The teachers told me their own stories, of overcoming prejudice and learning how to create a welcoming atmosphere. And the graduates told me THEIR stories, of what it took to succeed in those conditions, and how education--especially learning how to speak better-- transformed them, and they, in turn, transformed the entire culture and economy of the region

Acute Effects of Combination of IB and IC Antiarrhythmics for the Treatment of Ventricular Tachycardia

Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/97256/1/j.1552-4604.1989.tb03268.x.pd

Aortic dissection type I in a weightlifter with hypertension: A case report

Acute aortic dissection can occur at the time of intense physical exertion in strength-trained athletes like weightlifters, bodybuilders, throwers, and wrestlers