An Outbreak of the Saddled Prominent Caterpillar, \u3ci\u3eHeteocampa Guttivitta\u3c/i\u3e (Lepidoptera: Notodontidae) on Beaver Island, Michigan

(excerpt) In 1975 and 1976 an outbreak of the saddled prominent caterpillar, Heterocarnpa guttivitta (Walker) was observed in Beech-Maple climax forests on Beaver Island, Michigan. The adult guttivitta moths emerge in late May and early June, mate, and lay small (1 mm) eggs on the underside of leaves. One female lays about 500 of the green spheres. In 9-10 days the eggs hatch, and the larvae go through characteristic changes in form and markings through the following five instars (Allen, 1972)

Shall I Fill \u27er Up, Sir?: A Study of the Retail Gasoline Service Station Operator and Methods of Increasing his Profits

This 33 page thesis examines a proposal to increase sales at a gasoline service station

“Don’t Go Near the Water” (Coal Leasing on Public Lands)

5 pages

On P2X receptors in the brain: microvessels. Dedicated to the memory of the late Professor Geoffrey Burnstock (1929-2020)

This tribute article presents selected immunocytochemical and transmission electron microscope data on the location of ATP-gated P2X receptor in the rat brain, as studied in the 1990s in Prof G. Burnstock’s laboratory at University College London. There are examples of immuno-ultrastructural findings and introductory information about pre- and post-synaptic location of P2X receptors in the rat cerebellum and endocrine hypothalamus to support the concept of purinergic transmission in the central nervous system. Then findings of diverse immunoreactivity for P2X1, P2X2, P2X4, and P2X6 receptors associated with brain microvessels are shown, including vascular endothelium and pericytes as well as perivascular astrocytes and neuronal components. These findings imply the involvement of P2X receptors and hence purinergic signalling in the neurovascular unit, at least in microvessels in the rat cerebellum and hypothalamic paraventricular and supraoptic nuclei examined here. Various aspects of P2X receptors in brain microvessels are discussed

Conceptualizing Governance Decision Making: A Theoretical Model of Mental Processes Derived Through Abduction

The field of Public Policy and Administration is heavily influenced by the decisions individuals make regarding matters of governance. These types of decisions can affect a broad scope of government-related activities ranging from esoteric debates about political ideology to policy development to specific ways in which people directly interact with public services. Unfortunately, in the view of this research, there is no sufficient model for conceptualizing governance decision making. This creates the focus of inquiry for this work, which is to examine how governance decisions are conceived of and formulated. The purpose of this research is then to analyze the governance decision making processes. This is achieved by examining the available research on decision making processes and then contrasting the widely applied rational approaches with the more applicable nonrational approaches for decision making. This review will indicate that a nonrational conceptualization based on schemas, heuristics, and a societal-level shared mental model may be more instrumental in analyzing governance decisions than rational conceptualizations. The unique but necessary methodological approach of abductive logic is used to develop a theoretical foundation for this new perspective. An application of abductive principles is used to create a framework that anchors governance decisions. The result of these efforts is a model that can serve as a tool for analysis of these important and influential decisions in governance

Partially methylated alleles, microdeletion, and tissue mosaicism in a fragile X male with tremor and ataxia at 30 years of age: A case report

CGG repeat expansion >200 within FMR1, termed full mutation (FM), has been associated with promoter methylation, consequent silencing of gene expression and fragile X syndrome (FXS)-a common cause of intellectual disability and co-morbid autism. Unmethylated premutation (55-199 repeats) and FM alleles have been associated with fragile X related tremor/ataxia syndrome (FXTAS), a late onset neurodegenerative disorder. Here we present a 33-year-old male with FXS, with white matter changes and progressive deterioration in gait with cerebellar signs consistent with probable FXTAS; there was no evidence of any other cerebellar pathology. We show that he has tissue mosaicism in blood, saliva, and buccal samples for the size and methylation of his expanded alleles and a de novo, unmethylated microdeletion. This microdeletion involves a ∼80 bp sequence in the FMR1 promoter as well as complete loss of the CGG repeat in a proportion of cells. Despite FMR1 mRNA levels in blood within the normal range, the methylation and CGG sizing results are consistent with the diagnosis of concurrent FXS and probable FXTAS. The demonstrated presence of unmethylated FM alleles would explain the manifestation of milder than expected cognitive and behavioral impairments and early onset of cerebellar ataxia. Our case suggests that individuals with FXS, who manifest symptoms of FXTAS, may benefit from more detailed laboratory testing. © 2016 Wiley Periodicals, Inc

Science 2.0, e-Science, Cyberscience: Wissenschaft im Web 2.0

In Konferenzvorträgen, Blogposts und wissenschaftlichen Artikeln ist derzeit von einer neuen Form wissenschaftlichen Arbeitens die Rede, die mal als »Science 2.0«, mal als »e-Science« oder als »Cyberscience« bezeichnet wird. Darunter versteht man die verstärkte Nutzung von Web2.0-Diensten, z.B. Blogs, Wikis, soziale Netzwerke oder Online-Literaturverwaltungen durch Wissenschaftler. Die Auswirkungen sind z.B. veränderte Such- und Lesetechniken, starke Zunahme von Mehrautorenschaft bei wissenschaftlichen Publikationen oder die stärkere Verschmelzung von wissenschaftlicher Kommunikation und Publikationstätigkeit. – Der Vortrag beleuchtet verschiedene Werkzeuge, die das Neue Web der Wissenschaft derzeit anbietet und versucht dabei, deren Möglichkeiten und Grenzen aufzuzeigen. Weblinks: Mendeley: , Google Wave: , CiteULike: , Connotea: , Google Docs: , Bibsonomy: , ResearchGATE