Back to One City: The 1973 Memphis State Tigers and Myths of Race and Sport

In 1973, the then-Memphis State (now University of Memphis) Tigers’ Men\u27s Basketball team reached the NCAA tournament final. In the history of college basketball, Memphis State’s season is just a footnote, as the Tigers lost the title game to UCLA, which captured its seventh consecutive NCAA championship. But in Memphis, this team became a civic mythic legend. With each victory, the city’s enthusiasm ballooned, inspiring more paeans to players Larry Finch and Ronnie Robinson, coach Gene Bartow, and budding superstar Larry Kenon. Politicians and journalists upheld the team as a vehicle of interracial unity, healing the scars of the 1968 Sanitation Strike and Martin Luther King’s assassination. As with many myths, this one has elements of truth yet it hides as much as it reveals.https://egrove.olemiss.edu/studythesouth/1017/thumbnail.jp

Becoming Isis: Myth, Magic, Medicine, and Reproduction in Ancient Egypt

In ancient Egypt, sexuality, fertility, and the conception of children was of central importance not just to personal identity, but also to family and social structure. Because of the significance of birth in both the physical world and in the spiritual realm, references to reproduction, including fertility, conception, pregnancy, and childbirth, can be found in a wide variety of textual sources. Specifically, mythic events and scenarios, including those in magical spells, medico-magical spells, and funerary texts, reflected Egyptian reproductive conceptions and practices. Further, the Egyptians employed and called on these mythic episodes and archetypes to create divinely charged myth-mirroring space, spells, and remedies to manage reproductive events. Investigating this complex matrix of cultural ideas and practices reflected in text, augmented by data from select iconography, material culture, and human remains, this study resituates Egyptian reproductive lives within their own cultural context, through the Egyptians\u27 own terms and reproductive timeline. From conception to the child\u27s first breath, this study attempts to access the beliefs that would have informed and shaped the Egyptians reproductive experiences

Reading Primary Scientific Literature: Approaches for Teaching Students in the Undergraduate STEM Classroom

Teaching undergraduate students to read primary scientific literature (PSL) is cited as an important goal for many science, technology, engineering, and math (STEM) classes, given a range of cognitive and affective benefits for students who read PSL. Consequently, there are a number of approaches and curricular interventions published in the STEM education literature on how to teach students to read PSL. These approaches vary widely in their instructional methods, target student demographic, required class time, and level of assessment demonstrating the method\u27s efficacy. In this Essay, we conduct a systematic search to compile these approaches in an easily accessible manner for instructors, using a framework to sort the identified approaches by target level, time required, assessment population, and more. We also provide a brief review of the literature surrounding the reading of PSL in undergraduate STEM classrooms and conclude with some general recommendations for both instructors and education researchers on future areas of investigation

Book Reviews

Book reviews of: Hattiesburg: An American City in Black and White By William Sturkey. (Cambridge: Harvard University Press, 2019. Acknowledgements, illustrations, map, notes, index. Pp. 442. $29.95 cloth. ISBN 978-0-674-97635-1.) Confederate Generals in the Trans-Mississippi, Volume 3: Essays on America’s Civil War. Edited by Thomas E. Schott and Lawrence Lee Hewitt. (Knoxville: University of Tennessee Press, 2019. Maps, photos, notes, appendix, bibliography, index. Pp. xxiv, 374.$64.95 cloth. ISBN: 978-1-62190-454-0.) Mothers of Massive Resistance: White Women and the Politics of White Supremacy. By Elizabeth Gillespie McRae. (New York: Oxford University Press, 2018. Acknowledgements, Abbreviations, illustrations, notes, index. Pp. xiv, 343. $34.95 hardcover. ISBN: 978-0-19-027171-8.) Poll Power: The Voter Education Project and the Movement for the Ballot in the American South. By Evan Faulkenbury. (Chapel Hill: University of North Carolina Press, 2019. Acknowledgements, illustrations, notes, index. Pp. xi, 200.$90 cloth, $27.95 paper. ISBN: 978-1-4696-5131-6.) Let Us Make Men: The Twentieth Century Black Press and a Manly Vision for Racial Advancement. By D’Weston Haywood. (Chapel Hill: University of North Carolina Press, 2018. Acknowledgements, illustrations, map, notes, index. Pp. xi, 340.$55 cloth, $19.50 paper. ISBN: 978-1-4696-4338-0.) The Man Who Punched Jefferson Davis: The Political Life of Henry S. Foote, Southern Unionist. By Ben Wynne. (Baton Rouge, Louisiana State University Press, 2018. Acknowledgements, illustrations, notes, index. Pp. ix, 323.$47.50 cloth. ISBN: 978-0-8071-6933-9.) Desegregating Dixie: The Catholic Church in the South and Desegregation, 1945-1992. By Mark Newman. (Jackson: University Press of Mississippi, 2018. Acknowledgements, appendices, notes, bibliography, index. Pp. xvii, 455. $90 cloth,$30 paper. ISBN: 978-1-4968-1886-7.) The Loyal Republic: Traitors, Slaves, and the Remaking of Citizenship in Civil War America. By Erik Mathisen. (Chapel Hill: The University of North Carolina Press, 2018. Acknowledgments, illustrations, map, notes, index. Pp. xi, 219. $34.95 cloth. ISBN: 978-1-4696-3632-0.) Aberration of Mind: Suicide and Suffering in the Civil War-Era South. By Diane Miller Sommerville. (Chapel Hill: University of North Carolina Press, 2018. Acknowledgements, notes, bibliography, index. Pp. 448.$105 cloth, $34.95 paper. ISBN: 978-1-4696-4330-4.) Women’s War: Fighting and Surviving the American Civil War. By Stephanie McCurry. (Cambridge, Massachusetts: The Belknap Press of Harvard University Press, 2019. notes, acknowledgements, index. Pp ix, 297.$26.95 hardcover. ISBN: 978-0-674-98797-5.) Lines Were Drawn: Remembering Court-Ordered Integration at a Mississippi High School. Edited By Teena F. Horn, Alan Huffman, and John G. Jones. (Jackson: University Press of Mississippi, 2016. Acknowledgments, illustrations, map, notes, index. Pp. xi, 266. $35 hard back. ISBN: 978-1-62846-231-9.) Industrial Development and Manufacturing in the Antebellum Gulf South: A Reevaluation. By Michael S. Frawley. (Baton Rouge: Louisiana State University Press. 2019. ix, 256 pp. Cloth,$45.00, ISBN 978-0-8071-7068-7.) Integration Now: Alexander v. Holmes and the End of Jim Crow Education. By William P. Hustwit. (Chapel Hill: University of North Carolina Press, 2019. 8 halftones, 1 map, notes, bibl., index. 288 pp. $39.95, hardcover. ISBN: 978-1-4696-4855-2.

Effect of mivacurium 200 and 250 μg/kg in infants during isoflurane anesthesia: a randomized controlled trial [ISRCTN07742712]

BACKGROUND: Infants usually respond differently to a neuromuscular relaxant compared to children or adults. Isoflurane is commonly used as an anesthetic gas in infants. In an RCT design, we investigated whether a dose of mivacurium 250 μg/kg results in faster onset of action than 200 μg/kg in infants under isoflurane anesthesia. Spontaneous recovery times and cardiovascular response were also evaluated. METHODS: Twenty-four low surgical risk children, aged 6–24 months, undergoing an elective surgery and requiring tracheal intubation were selected. After anesthetic induction, patients randomly received an iv bolus dose of mivacurium 200 or 250 μg/kg. After maximal relaxation, the patient was intubated. Isoflurane was administered to maintain anesthetic level during the surgical procedure. Neuromuscular function was monitored by accelerometry (TOF-Guard) at the adductor pollicies. The first twitch (T) of the TOF and the T4/T1 were measured. The time-course of heart rate and systolic and diastolic blood pressure were analysed by transforming them into their respective areas under the curve. RESULTS: Mivacurium 250 μg/kg produced a maximal T block faster than 200 μg/kg, i.e. 2.4 ± 1.1 vs. 3.5 ± 1.4 min (p < 0.05). Spontaneous recovery times were similar in both groups. Heart rate was similar between doses while systolic and diastolic blood pressures were lower with the higher dose (p < 0.05). Flushing was observed in two cases, one in each group. CONCLUSIONS: The maximal effect of mivacurium 250 μg/kg, in infants under isoflurane anesthesia, was present one minute faster than 200 μg/kg. However, it produced a significant cardiovascular response

Cdk1-Dependent Phosphorylation of Cdc13 Coordinates Telomere Elongation during Cell-Cycle Progression

SummaryElongation of telomeres by telomerase replenishes the loss of terminal telomeric DNA repeats during each cell cycle. In budding yeast, Cdc13 plays an essential role in telomere length homeostasis, partly through its interactions with both the telomerase complex and the competing Stn1-Ten1 complex. Previous studies in yeast have shown that telomere elongation by telomerase is cell cycle dependent, but the mechanism underlying this dependence is unclear. In S. cerevisiae, a single cyclin-dependent kinase Cdk1 (Cdc28) coordinates the serial events required for the cell division cycle, but no Cdk1 substrate has been identified among telomerase and telomere-associated factors. Here we show that Cdk1-dependent phosphorylation of Cdc13 is essential for efficient recruitment of the yeast telomerase complex to telomeres by favoring the interaction of Cdc13 with Est1 rather than the competing Stn1-Ten1 complex. These results provide a direct mechanistic link between coordination of telomere elongation and cell-cycle progression in vivo

Shelterin-Like Proteins and Yku Inhibit Nucleolytic Processing of Saccharomyces cerevisiae Telomeres

Eukaryotic cells distinguish their chromosome ends from accidental DNA double-strand breaks (DSBs) by packaging them into protective structures called telomeres that prevent DNA repair/recombination activities. Here we investigate the role of key telomeric proteins in protecting budding yeast telomeres from degradation. We show that the Saccharomyces cerevisiae shelterin-like proteins Rif1, Rif2, and Rap1 inhibit nucleolytic processing at both de novo and native telomeres during G1 and G2 cell cycle phases, with Rif2 and Rap1 showing the strongest effects. Also Yku prevents telomere resection in G1, independently of its role in non-homologous end joining. Yku and the shelterin-like proteins have additive effects in inhibiting DNA degradation at G1 de novo telomeres, where Yku plays the major role in preventing initiation, whereas Rif1, Rif2, and Rap1 act primarily by limiting extensive resection. In fact, exonucleolytic degradation of a de novo telomere is more efficient in yku70Δ than in rif2Δ G1 cells, but generation of ssDNA in Yku-lacking cells is limited to DNA regions close to the telomere tip. This limited processing is due to the inhibitory action of Rap1, Rif1, and Rif2, as their inactivation allows extensive telomere resection not only in wild-type but also in yku70Δ G1 cells. Finally, Rap1 and Rif2 prevent telomere degradation by inhibiting MRX access to telomeres, which are also protected from the Exo1 nuclease by Yku. Thus, chromosome end degradation is controlled by telomeric proteins that specifically inhibit the action of different nucleases