Multilevel modelling of refusal and non-contact in household surveys: evidence from six UK Government surveys

We analyse household unit non-response in six major UK Government surveys by using a multilevel multinomial modelling approach. The models are guided by current conceptual frameworks and theories of survey participation. One key feature of the analysis is the investigation of the extent to which effects of household characteristics are survey specific. The analysis is based on the 2001 UK Census Link Study, which is a unique source of data containing an unusually rich set of auxiliary variables. The study contains the response outcome of six surveys, linked to census data and interviewer observations for both respondents and non-respondents

Can children resist making interpretations when uncertain?

In two experiments we examined young children’s ability to delay a response to ambiguous input. In Experiment 1 5- and 6- year olds performed as poorly when they had to choose between basing an interpretation on ambiguous input and delaying an interpretation as when making explicit evaluations of knowledge. Seven- and 8- year olds’ found the former task easy. In Experiment 2 5- and 6- year olds performed well on a task that required delaying a response but removed the need to decide between strategies. We discuss children’s difficulty with ambiguity in terms of the decision making demands made by different procedures. These demands appear to cause particular problems for young children

Do gaze cues in complex scenes capture and direct the attention of high functioning adolescents with ASD? evidence from eye-tracking

Visual fixation patterns whilst viewing complex photographic scenes containing one person were studied in 24 high-functioning adolescents with Autism Spectrum Disorders (ASD) and 24 matched typically developing adolescents. Over two different scene presentation durations both groups spent a large, strikingly similar proportion of their viewing time fixating the person’s face. However, time-course analyses revealed differences between groups in priorities of attention to the region of the face containing the eyes. It was also noted that although individuals with ASD were rapidly cued by the gaze direction of the person in the scene, this was not followed by an immediate increase in total fixation duration at the location of gaze, which was the case for typically developing individuals

The eye gaze direction of an observed person can bias perception, memory, and attention in adolescents with and without autism spectrum disorder

The reported experiments aimed to investigate whether a person and his or her gaze direction presented in the context of a naturalistic scene cause perception, memory, and attention to be biased in typically developing adolescents and high-functioning adolescents with autism spectrum disorder (ASD). A novel computerized image manipulation program presented a series of photographic scenes, each containing a person. The program enabled participants to laterally maneuver the scenes behind a static window, the borders of which partially occluded the scenes. The gaze direction of the person in the scenes spontaneously cued attention of both groups in the direction of gaze, affecting judgments of preference (Experiment 1a) and causing memory biases (Experiment 1b). Experiment 2 showed that the gaze direction of a person cues visual search accurately to the exact location of gaze in both groups. These findings suggest that biases in preference, memory, and attention are caused by another person's gaze direction when viewed in a complex scene in adolescents with and without ASD (C) 2009 Elsevier Inc. All rights reserved

The eye gaze direction of an observed person can bias perception, memory, and attention in adolescents with and without autism spectrum disorder

The reported experiments aimed to investigate whether a person and his or her gaze direction presented in the context of a naturalistic scene cause perception, memory, and attention to be biased in typically developing adolescents and high-functioning adolescents with autism spectrum disorder (ASD). A novel computerized image manipulation program presented a series of photographic scenes, each containing a person. The program enabled participants to laterally maneuver the scenes behind a static window, the borders of which partially occluded the scenes. The gaze direction of the person in the scenes spontaneously cued attention of both groups in the direction of gaze, affecting judgments of preference (Experiment 1a) and causing memory biases (Experiment 1b). Experiment 2 showed that the gaze direction of a person cues visual search accurately to the exact location of gaze in both groups. These findings suggest that biases in preference, memory, and attention are caused by another person's gaze direction when viewed in a complex scene in adolescents with and without ASD (C) 2009 Elsevier Inc. All rights reserved

Interprofessional learning in practice: The student experience

Interprofessional learning and the development of teamworking skills are recognised as essential for patient care and are also a government priority for undergraduate education. Sixteen occupational therapy students worked on an interprofessional training ward as part of their practice placement and three of them participated in an evaluation using the nominal group technique. Despite this small number, the evaluation identifies the value of this learning experience in giving the students an opportunity to appreciate the importance of interpersonal skills; to learn about other team members’ roles; and to experience the challenges of working on a busy rehabilitation ward for older people

The interactions of viral matrix proteins with lipid membranes

This thesis describes the work undertaken to study the binding of lipid membranes by the viral matrix proteins hRSV-M and Influenza-A-M1. hRSV-M was recombinantly expressed and purified. It was the subjected to analysis by Langmuir-Blodgett trough experiments, Brewster angle microscopy, Confocal microscopy of giant unilamellar vesicles (GUVs), and binding studies with lipid nanodiscs. These studies showed hRSV-M having a preference for interacting with negatively charged lipids, namely phosphatidylserine, and for having different behaviours in Lo and Ld phases of membranes. During work on hRSV-M to improve its stability, it was discovered calcium stabilised the protein. This relationship was explored by ICPMS, differential scanning fluorimetry (DSF), circular dichroism (CD), mass spectrometry and microscale thermophoresis. This showed the hRSV-M is a calcium binding protein, containing two binding sites. Influenza-A-M1 was cloned into a plasmid vector and subsequently expressed and purified. The stability and structure of the protein was probed by DSF and CD measurements. The lipid interactions of this protein were then also explored by Langmuir-Blodgett trough isotherms and GUV binding under confocal microscopy. These showed that M1 is able to bind to phosphatidylserine containing membranes and causes vesicle budding from those membranes

Dingo control in the Kimberley Region

With all the recent dramatic developments in irrigated agriculture in the Kimberley region of Western Australia, one is apt to forget the main wealth of the district still lies in its pastoral industry. Man, in his efforts to obtain a living from the pastoral industry, has to contend with many pests which compete with pastoral activities. Perhaps the most serious and certainly the most sagacious pest in this region is the dingo