A life-changing internship and the power of experiential learning

Learning through experience is a powerful and important opportunity for undergraduate students. In this editorial, The University of Texas at Austin (UT Austin) President Greg Fenves details the short- and long-term significance of experience-based learning for students’ development. Throughout Fenves’ career, experiential learning has played a significant role for him, shaping both his career path and his priorities as a professor, provost, and, now, university president. In this piece, Fenves shares his experiences and describes why experiential learning is one of his priorities for UT Austin students.Educatio

Automatic Analyzer for Iterative Design

The Office of Naval Research Department Of The Navy Contract Nonr 1834 (03) Project NR-064-18

Final Report

AASHO Road TestHighway Research BoardNational Academy of Sciences - National Research Counci

Decision Table Formulation of The 1969 Aisc Specification

The American Institute of Steel Constructio

2019 State of the University Address

The University of Texas at Austin writes about Good Systems in the 2019 State of the University Address in an article published in 2019.Office of the VP for Researc

Aura und Irrtum:Das Problem der Popularisierung von Benjamin bis Heidegger

Der Philosoph und Komparatist Peter Fenves befasst sich in seinem Aufsatz mit Benjamins Ideen zur Wissenschaftspopularisierung und seiner Auseinandersetzung mit der theoretischen Physik. Er widmet sich insbesondere Benjamins Verteidigung der in Misskredit stehenden Wissenschaftspopularisierung, die eine neue Bedeutung und Funktion erhalten soll. Die latenten Bezüge zwischen Philosophie und theoretischer Physik zeigt Fenves am Beispiel des in der Quantenphysik verwendeten Begriffs der »Verschränkung« auf, der das Pendant zu Benjamins Begriff der »Aura« darstellt und zur gleichen Zeit von Heidegger verwendet wird.Peter Fenves, »Aura und Irrtum: Das Problem der Popularisierung von Benjamin bis Heidegger«, in Aura und Experiment: Naturwissenschaft und Technik bei Walter Benjamin, hg. v. Kyung-Ho Cha, Cultural Inquiry, 13 (Wien: Turia + Kant, 2017), S. 61–77 <https://doi.org/10.37050/ci-13_04

Focal segmental glomerulosclerosis associated with mitochondrial disease

Primary mitochondrial diseases (MD) are complex, heterogeneous inherited diseases caused by mutations in either the mitochondrial or nuclear DNA. Glomerular diseases in MD have been reported with tRNA mutation m.3243A>G causing a syndrome of mitochondrial encephalomyopathy, lactic acidosis and stroke-like episodes (MELAS). We describe here a case of focal segmental glomerulosclerosis (FSGS) associated with a new tRNA mutation site. A 34-year-old man with a history of living related kidney transplantation, diabetes, hearing loss, and developmental delay presented to the outpatient clinic with complaints of new behavioral difficulties, worsening symptoms, and brain involvement on imaging. Physical examination was remarkable for difficulty hearing, a pattern of dysarthric speech, and cerebellar gait. Laboratory investigations including lactate levels were unremarkable. Based on this set of clinical circumstances, concern for an underlying genetic abnormality was raised. Multiple metabolic tests were unremarkable. Whole exome sequencing revealed a mitochondrial MT-TW tRNA change at position m.5538G>A. Genotype-phenotype correlations are consistent with this tRNA mutation as a cause of his symptoms. To the best of our knowledge, this is the first case describing FSGS-associated MD caused by an m.5538 G>A mutation. Consideration of an underlying MD should be made in patients presenting with deafness, neurologic changes, diabetes, and renal failure

Post-infection immunocomplex glomerulonephritis and Legionnaires' disease in a patient with adult Still's disease during treatment with interleukin 1 receptor antagonist anakinra: a case report

<p>Abstract</p> <p>Introduction</p> <p>Legionellosis is a systemic disease that primarily affects the lungs. However, dysfunction in many organ systems, including the kidneys, has also been described. There are only a few reported cases of renal dysfunction in patients with legionellosis.</p> <p>Case presentation</p> <p>A 27-year-old Caucasian woman with known adult Still's disease was admitted to our hospital for community-acquired pneumonia, due to <it>Legionella </it>infection, with acute renal failure. Although her respiratory symptoms responded well to antibiotic treatment, her renal function worsened, with severe proteinuria and edema. A renal biopsy showed extracapillary and endocapillary proliferative glomerulonephritis with accompanying chronic and acute interstitial nephritis. This was consistent with a post-infection immunocomplex glomerulonephritis. After initiation of steroid therapy, her renal function improved. Additionally, therapy with diuretics and an angiotensin-converting enzyme inhibitor was initiated because of persistent proteinuria. Under this treatment regimen, her severe edema and proteinuria disappeared.</p> <p>Conclusion</p> <p>To the best of our knowledge, there is only a handful of reported cases of post-infection glomerulonephritis with a nephrotic syndrome in a patient with legionellosis. Our findings suggest that, in patients with Legionnaires' disease with renal failure, post-infection immunocomplex glomerulonephritis should be considered and steroid therapy may be an effective modality to treat the renal complication.</p