37 research outputs found

    Enzymatic formation of protopines by a microsomal cytochrome P-450 system of Corydalis vaginans

    Get PDF
    A microsomal cytochrome P-450-NADPH dependent enzyme which hydroxylates stereo- and regiospecifically carbon atom 14 of (S)- -N- methyltetrahydroprotoberberines has been discovered in a number of plant cell cultures originating from species containing protopine alkaloids; the monooxygenase was solubilized, partially purified (100-fold) and characterized
    corecore