93 research outputs found
Transtorno do desenvolvimento da coordenação e senso de auto-eficácia: implicações para a prática da terapia ocupacional
No transtorno do desenvolvimento da coordenação há um prejuízo acentuado no desenvolvimento das habilidades motoras (grossas e/ou finas) de crianças, com impacto na participação em atividades típicas da infância. As conseqüências do transtorno também incluem restrição na interação social e baixo senso de auto-eficácia. Terapeutas ocupacionais, embora habilitados a avaliar e tratar crianças com esse perfil, aparentam desconhecer a importância do senso de auto-eficácia, assim como seus instrumentos de avaliação. Desta forma, o objetivo desta revisão é apontar a relação entre o desempenho motor e o senso de eficácia de crianças com TDC em idade escolar, bem como suas possíveis implicações para a prática da Terapia Ocupacional.Developmental Coordination Disorder (DCD) is characterized by a marked deficit in the development of children's motor skills (gross and/or fine), with impact in the participation in typical activities of the childhood. Consequences of the disorder include restriction in social interaction and low sense of self-efficacy. Although occupational therapists are able to evaluate and treat children with this profile, they don't seem to know the importance of the sense of self-efficacy, as well as its assessment tools. In this way, this review points to the relation between the motor performance and the sense of efficacy of children with DCD in school age, as well as its possible implications for Occupational Therapy's practice
The preburning condition of Chalcolithic cremated human remains from the Perdigoes enclosures (Portugal)
The Iberian Chalcolithic displayed a remarkable variety of funerary practices, which has been related to interpopulation differences, intrapopulation social-cultural differences, and complex multistage funerary rituals. Perdigoes, a Chalcolithic set of ditched enclosures, reflects such diversity including a wide array of funerary practices. Among those practices is cremation, which, despite relatively rare, is represented in different structures in Perdigoes. One of these structures (Pit 40) presents an unparalleled high minimum number of individuals (n = 240), contrasting with nearby and coeval structures. In this study, we analyse heat-induced bone changes and other archaeothanatological variables to tentatively assess the preburning condition of the human remains. The results of Pit 40 are also compared with other comparable contexts to assess if this unique context presents further funerary differences relative to those other contexts in, for example, body processing. Our results suggest preferential cremation of fleshed human remains, but burning of at least a minority of skeletonised remains and deposition of possibly unburned remains also likely occurred. Body processing appears to be comparable with that of the cremation contexts of Perdigoes but contrasts with that of another nearby context (Dolmen of Olival da Pega 2b) in which burned bones were also found.Portuguese Foundation for Science and TechnologyPortuguese Foundation for Science and Technology [PEst-OE/SADG/UI0283/2013, POCI-01-0145-FEDER-016766, PTDC/EPH-ARQ/0798/2014, PTDC/IVC-ANT/1201/2014, SFRH/BPD/84268/2012]info:eu-repo/semantics/publishedVersio
Control of Flowering and Cell Fate by LIF2, an RNA Binding Partner of the Polycomb Complex Component LHP1
Polycomb Repressive Complexes (PRC) modulate the epigenetic status of key cell fate and developmental regulators in eukaryotes. The chromo domain protein LIKE HETEROCHROMATIN PROTEIN1 (LHP1) is a subunit of a plant PRC1-like complex in Arabidopsis thaliana and recognizes histone H3 lysine 27 trimethylation, a silencing epigenetic mark deposited by the PRC2 complex. We have identified and studied an LHP1-Interacting Factor2 (LIF2). LIF2 protein has RNA recognition motifs and belongs to the large hnRNP protein family, which is involved in RNA processing. LIF2 interacts in vivo, in the cell nucleus, with the LHP1 chromo shadow domain. Expression of LIF2 was detected predominantly in vascular and meristematic tissues. Loss-of-function of LIF2 modifies flowering time, floral developmental homeostasis and gynoecium growth determination. lif2 ovaries have indeterminate growth and produce ectopic inflorescences with severely affected flowers showing proliferation of ectopic stigmatic papillae and ovules in short-day conditions. To look at how LIF2 acts relative to LHP1, we conducted transcriptome analyses in lif2 and lhp1 and identified a common set of deregulated genes, which showed significant enrichment in stress-response genes. By comparing expression of LHP1 targets in lif2, lhp1 and lif2 lhp1 mutants we showed that LIF2 can either antagonize or act with LHP1. Interestingly, repression of the FLC floral transcriptional regulator in lif2 mutant is accompanied by an increase in H3K27 trimethylation at the locus, without any change in LHP1 binding, suggesting that LHP1 is targeted independently from LIF2 and that LHP1 binding does not strictly correlate with gene expression. LIF2, involved in cell identity and cell fate decision, may modulate the activity of LHP1 at specific loci, during specific developmental windows or in response to environmental cues that control cell fate determination. These results highlight a novel link between plant RNA processing and Polycomb regulation
Recommended from our members
Measurement of Gas and Liquid Velocities in an Air-Water Two-Phase Flow using Cross-Correlation of Signals from a Double Senor Hot-Film Probe
Local gas and liquid velocities are measured by cross-correlating signals from a double sensor hot-film anemometer probe in pure water flow and air water two-phase flow. The gas phase velocity measured in two-phase flow agrees with velocity data obtained using high-speed video to within +/-5%. A turbulent structure, present in the liquid phase, allows a correlation to be taken, which is consistent with the expected velocity profiles in pure liquid flow. This turbulent structure is also present in the liquid phase of a two-phase flow system. Therefore, a similar technique can be applied to measure the local liquid velocity in a two-phase system, when conditions permit
Experimental design approach for the solid-phase extraction of residual aluminium coagulants in treated waters
International audienc
Contamination spatiale et risques sanitaires liés à la présence de métaux (ou métalloïdes) à la surface de sols jouxtant le complexe pétrochimique d'Arzew dans le nord-est de l'Algérie
International audienceThe spatial distribution patterns, origins and environmental and health risks of metal trace elements (As, Cd, Co, Cr, Cu, Ni, Pb, Zn) have been analyzed through the spiking and the analysis of 84 soils sampled in the region of Arzew (Algeria). This city gathers one of the biggest petroleum harbors of Algeria and gathers in the same platform several industries, coexisting with residential and agricultural areas. The mean concentration of all the metals studied exceed their corresponding backgrounds levels and/or exceed the ecological Predicted No effect Concentration (PNEC) values. The geo-accumulation and the potential ecological risk indices indicate a low to moderate risk for As, Co, Cu, Ni and Zn, and a moderate to considerable risk for Cr and Pb. According to the health risk assessment results, the carcinogenic risks due to Cr exceed the acceptable level in all the functional areas, and when considering combined effects of metals, the hazard index obtained show a high potential carcinogenic risk to the local children
- …