Modelling survival and connectivity of Mnemiopsis leidyi in the south-western North Sea and Scheldt estuaries

Three different models were applied to study the reproduction, survival and dispersal of Mnemiopsis leidyi in the Scheldt estuaries and the southern North Sea: a high-resolution particle tracking model with passive particles, a low-resolution particle tracking model with a reproduction model coupled to a biogeochemical model, and a dynamic energy budget (DEB) model. The results of the models, each with its strengths and weaknesses, suggest the following conceptual situation: (i) the estuaries possess enough retention capability to keep an overwintering population, and enough exchange with coastal waters of the North Sea to seed offshore populations; (ii) M. leidyi can survive in the North Sea, and be transported over considerable distances, thus facilitating connectivity between coastal embayments; (iii) under current climatic conditions, M. leidyi may not be able to reproduce in large numbers in coastal and offshore waters of the North Sea, but this may change with global warming; however, this result is subject to substantial uncertainty. Further quantitative observational work is needed on the effects of temperature, salinity and food availability on reproduction and on mortality at different life stages to improve models such as used here

The use of genetic markers in poultry breeding

This thesis focuses on the design of linkage and quantitative trait locus (QTL) mapping experiments and on the use of genetic markers in poultry breeding schemes. Criteria to optimize the design of experiments that use outbred populations to create a linkage map were described. Those criteria were used to evaluate designs of experiments to map codominant and dominant genetic markers using half-sib of full-sib family structures. Once a linkage map is created, QTLs can be placed on the map. Deterministic computation methods were used to determine the power of two- and three- generation QTL mapping experiments in an outbred population containing full-sib or half-sib families. Genetic markers that are linked to QTL can be used for selection purposes. The effect of using genetic markers to assist selection in an outbred poultry breeding nucleus was studied. The additional response to selection for a sex-limited trait was computed using deterministic simulation. The general discussion of this thesis addresses the status of the chicken linkage map, QTLs found in poultry, and discusses the usefulness of several applications of genetic markers in poultry breeding

Supercooling of the high field vortex phase in single crystalline BSCCO

Time resolved magneto-optical images show hysteresis associated with the transition at the so-called ``second magnetization peak'' at B_sp in single-crystalline Bi_2Sr_2CaCu_2O_8+d. By rapid quenching of the high-field phase, it can be made to persist metastably in the sample down to fields that are nearly half B_sp.Comment: 2 pages, 2 figures Submitted to the conference proceedings of M2S-VI, February 200, Housto

Design of a randomized controlled trial on the effects of Counseling of mental health problems by Occupational Physicians on return to work: the CO-OP-study

Mental health problems often lead to prolonged sick leave. In primary care, the usual approach towards these patients was the advice to take rest and not return to work before all complaints had disappeared. When complaints persist, these patients are often referred to psychologists from primary and specialized secondary care. As an alternative, ways have been sought to activate the Dutch occupational physician (OP) in primary care. Early 2000, the Dutch Association of Occupational Physicians (NVAB) published a guideline concerning the management by OPs of employees with mental health problems. The guideline received positive reactions from employees, employers and Dutch OPs. This manuscript describes the design of a study, which aims to assess the effects of the guideline, compared with usual care. In a randomized controlled trial (RCT), subjects in the intervention group were treated according to the guideline. The control group received usual care, with minimal involvement of the OP and easy access to a psychologist. Subjects were recruited from two Dutch police departments. The primary outcomes of the study are return to work and treatment satisfaction by the employee, employer, and OP. A secondary outcome is cost-effectiveness of the intervention, compared with usual care. Furthermore, prognostic measures are taken into account as potential confounders. A process evaluation will be done by means of performance indicators, based on the guideline. In this pragmatic trial, effectiveness instead of efficacy is studied. We will evaluate what is possible in real clinical practice, rather than under ideal circumstances. Many requirements for a high quality trial are being met. Results of this study will contribute to treatment options in occupational health practice for employees on sick leave due to mental health problems. Additionally, they may contribute to new and better-suited guidelines and stepped care. Results will become available during 2007. Current Controlled Trials ISRCTN3488734

Vortex Solid-Liquid Transition in Bi2_{2}Sr2_{2}CaCu2_{2}O8+δ_{8+\delta} with a High Density of Strong Pins

The introduction of a large density of columnar defects in %underdoped Bi$_{2}$Sr$_{2}$CaCu$_{2}$O$_{8+\delta}$ crystals does not, at sufficiently low vortex densities, increase the irreversibility line beyond the first order transition (FOT) field of pristine crystals. At such low fields, the flux line wandering length $r_{w}$ behaves as in pristine %Bi$_{2}$Sr$_{2}$CaCu$_{2}$O$_{8+\delta}$ crystals. Next, vortex positional correlations along the $c$--axis in the vortex Bose glass at fields above the FOT are smaller than in the low--field vortex solid. Third, the Bose-glass-to-vortex liquid transition is signaled by a rapid decrease in c-axis phase correlations. These observations are understood in terms of the ``discrete superconductor'' model.Comment: 4 pages, 4 figures Submitted to Phys. Rev. B Rapid Comm. 16-1-2004 Revised version 18-3-200

Magnetization Decay due to Vortex Phase Boundary Motion in BSCCO

We identify a new regime of decay of the irreversible magnetization in clean Bi$_{2}$Sr$_{2}$CaCu$_{2}$O$_{8}$ crystals, at induction values close to the ``second peak field'' at which the bulk critical current density steeply increases. A time window is identified during which the decay of the induction is controlled by the slow propagation of the phase transformation front across the sample.Comment: 2 pages, 3 figures Paper submitted to the conference proceedings of M2S-2000 Houston T

Magnetic relaxation in the "Bragg-glass" phase in BSCCO

Magnetic relaxation in the Bragg-glass phase of overdoped Bi_2Sr_2CaCu_2O_8 crystals was investigated using time-resolved magneto-optical visualisation of the flux distribution. This has permitted us to extract the current-voltage characteristic, which can be well described by a power-law, although fits to a stretched exponential E \sim \exp(- j_{c} / j)^{\mu} with 0.3 < \mu < 0.8 are possible at long times in excess of 100 s.Comment: 2 pages, 3 figures submitted to conference proceedings of M2S-2000 Houston T

Thermodynamics of a Heavy Ion-Irradiated Superconductor: the Zero-Field Transition

Specific heat measurements show that the introduction of amorphous columnar defects considerably affects the transition from the normal to the superconducting state in zero magnetic field. Experimental results are compared to numerical simulations of the 3D XY model for both the pure system and the system containing random columnar disorder. The numerics reproduce the salient features of experiment, showing in particular that the specific heat peak changes from cusp-like to smoothly rounded when columnar defects are added. By considering the specific heat critical exponent alpha, we argue that such behavior is consistent with recent numerical work [Vestergren et al., PRB 70, 054508 (2004)] showing that the introduction of columnar defects changes the universality class of the transition.Comment: 4 pages, 2 figure