758 research outputs found
Spin dynamics and disorder effects in the S=1/2 kagome Heisenberg spin liquid phase of kapellasite
We report Cl NMR, ESR, SR and specific heat measurements on the
frustrated kagom\'e magnet kapellasite,
CuZn(OH)Cl, where a gapless spin liquid phase is
stabilized by a set of competing exchange interactions. Our measurements
confirm the ferromagnetic character of the nearest-neighbour exchange
interaction and give an energy scale for the competing interactions K. The study of the temperature-dependent ESR lineshift reveals a
moderate symmetric exchange anisotropy term , with %. These
findings validate a posteriori the use of the Heisenberg
model to describe the magnetic properties of kapellasite [Bernu et al., Phys.
Rev. B 87, 155107 (2013)]. We further confirm that the main deviation from this
model is the severe random depletion of the magnetic kagom\'e lattice by 27%,
due to Cu/Zn site mixing, and specifically address the effect of this disorder
by Cl NMR, performed on an oriented polycrystalline sample.
Surprisingly, while being very sensitive to local structural deformations, our
NMR measurements demonstrate that the system remains homogeneous with a unique
spin susceptibility at high temperature, despite a variety of magnetic
environments. Unconventional spin dynamics is further revealed by NMR and
SR in the low-, correlated, spin liquid regime, where a broad
distribution of spin-lattice relaxation times is observed. We ascribe this to
the presence of local low-energy modes.Comment: 15 pages, 11 figures. To appear in Phys. Rev.
On the Role of Penning Ionization in Photoassociation Spectroscopy
We study the role of Penning ionization on the photoassociation spectra of
He(^3S)-He(^3S). The experimental setup is discussed and experimental results
for different intensities of the probe laser are shown. For modelling the
experimental results we consider coupled-channel calculations of the crossing
of the ground state with the excited state at the Condon point. The
coupled-channel calculations are first applied to model systems, where we
consider two coupled channels without ionization, two coupled channels with
ionization, and three coupled channels, for which only one of the excited
states is ionizing. Finally, coupled-channel calculations are applied to
photoassociation of He(^3S)-He(^3S) and good agreement is obtained between the
model and the experimental results.Comment: 14 pages, 18 figures, submitted to the special issue on Cold
Molecules of J. Phys.
Listening to ironically-enjoyed music: A self-regulatory perspective
This research examines adults’ reported motivations for listening to music that they enjoy ironically. In a pilot (N = 96) and main (N = 175) studies, open-ended responses from adults were analysed using Thematic Analysis. Based on the pilot study, ironically enjoyed music was defined as “Music that is enjoyed because of being bad, despite being bad, or for different reasons than intended.” Although many relevant self-regulatory functions of listening to music in general were also relevant to ironically- enjoyed music, it also emerged that ironic enjoyment of music has characteristics that are unique to it: the additional role of mocking, ridiculing, and laughing at the music, and the social benefit that this provides. Music that was listened to “because of” its negative features had a variety of musical features, and the listening usually served functions unique to ironic enjoyment of music, such as mockery. When music was listened to “despite” negative qualities, the music itself was often described as having attractive rhythm, melody or lyrics, while the irony protected the listener from conflicting values associated with the music, helping the listener communicate to others that they did not identify with the music on a higher level. Unfamiliar music mainly played a social role, whereas familiar music related to nostalgia as well as most other functions
Precision requirements for interferometric gridding in the analysis of a 21 cm power spectrum
Context. Experiments that try to observe the 21 cm redshifted signals from the epoch of reionisation (EoR) using interferometric low-frequency instruments have stringent requirements on the processing accuracy.
Aims. We analyse the accuracy of radio interferometric gridding of visibilities with the aim to quantify the power spectrum bias caused by gridding. We do this ultimately to determine the suitability of different imaging algorithms and gridding settings for an analysis of a 21 cm power spectrum.
Methods. We simulated realistic Low-Frequency Array (LOFAR) data and constructed power spectra with convolutional gridding and w stacking, w projection, image-domain gridding, and without w correction. These were compared against data that were directly Fourier transformed. The influence of oversampling, kernel size, w-quantization, kernel windowing function, and image padding were quantified. The gridding excess power was measured with a foreground subtraction strategy, for which foregrounds were subtracted using Gaussian progress regression, as well as with a foreground avoidance strategy.
Results. Constructing a power spectrum with a significantly lower bias than the expected EoR signals is possible with the methods we tested, but requires a kernel oversampling factor of at least 4000, and when w-correction is used, at least 500 w-quantization levels. These values are higher than typically used values for imaging, but they are computationally feasible. The kernel size and padding factor parameters are less crucial. Of the tested methods, image-domain gridding shows the highest accuracy with the lowest imaging time.
Conclusions. LOFAR 21 cm power spectrum results are not affected by gridding. Image-domain gridding is overall the most suitable algorithm for 21 cm EoR power spectrum experiments, including for future analyses of data from the Square Kilometre Array (SKA) EoR. Nevertheless, convolutional gridding with tuned parameters results in sufficient accuracy for interferometric 21 cm EoR experiments. This also holds for w stacking for wide-field imaging. The w-projection algorithm is less suitable because of the requirements for kernel oversampling, and a faceting approach is unsuitable because it causes spatial discontinuities
Fabrication and characterization of pillar-based photonic crystal waveguides
We present the fabrication and optical characterization of waveguides in photonic crystals
based on pillars. The waveguides were integrated in a classical photonic integrated
circuit in InP technology. Photonic crystal waveguides of varying lengths were fabricated
and measured. From 2D band diagram simulations, two different defect radii were
selected while keeping the background photonic crystal the same. The waveguide with
the larger defect radius (rdefect = 210 nm) shows lower coupling losses than the waveguide with rdefect = 170 nm. This is in agreement with simulations on the photonic crystal waveguides
First LOFAR results on galaxy clusters
Deep radio observations of galaxy clusters have revealed the existence of
diffuse radio sources related to the presence of relativistic electrons and
weak magnetic fields in the intracluster volume. The role played by this
non-thermal intracluster component on the thermodynamical evolution of galaxy
clusters is debated, with important implications for cosmological and
astrophysical studies of the largest gravitationally bound structures of the
Universe. The low surface brightness and steep spectra of diffuse cluster radio
sources make them more easily detectable at low-frequencies. LOFAR is the first
instrument able to detect diffuse radio emission in hundreds of massive galaxy
clusters up to their formation epoch. We present the first observations of
clusters imaged by LOFAR and the huge perspectives opened by this instrument
for non-thermal cluster studies.Comment: Proceedings of the 2012 week of the French Society of Astronomy and
Astrophysics (SF2A) held in Nice, June 5th-8t
KRAS mutation analysis: a comparison between primary tumours and matched liver metastases in 305 colorectal cancer patients
Contains fulltext :
96042.pdf (publisher's version ) (Open Access)BACKGROUND: KRAS mutation is a negative predictive factor for treatment with anti-epidermal growth factor receptor antibody in metastatic colorectal cancer (CRC). KRAS mutation analysis is usually performed on primary tumour tissue because metastatic tissue is often not available. However, controversial data are available on the concordance of test results between primary tumours and corresponding metastases. We assessed the concordance of KRAS mutation status in a study of 305 primary colorectal tumours and their corresponding liver metastases. METHODS: Patients with histologically confirmed CRC who underwent surgical resection of the primary tumour and biopsy or surgical resection of the corresponding liver metastasis were included. KRAS mutation analysis was performed for codons 12 and 13. RESULTS: KRAS mutation was detected in 108 out of 305 primary tumours (35.4%). In 11 cases (3.6%), we found a discordance between primary tumour and metastasis: 5 primary tumours had a KRAS mutation with a wild-type metastasis, 1 primary tumour was wild type with a KRAS mutation in the metastasis, and in 5 cases the primary tumour and the metastasis had a different KRAS mutation. CONCLUSION: We observed a high concordance of KRAS mutation status of 96.4% (95% CI 93.6-98.2%) between primary colorectal tumours and their corresponding liver metastases. In only six patients (2.0%; 95% CI 0.7-4.2%), the discordance was clinically relevant. In this largest and most homogenous study to date, we conclude that both primary tumours and liver metastases can be used for KRAS mutation analysis
Least Upper Delay Bound for VBR Flows in Networks-on- Chip with Virtual Channels
Real-time applications such as multimedia and gaming require stringent performance guarantees, usually enforced by a tight upper bound on the maximum end-to-end delay. For FIFO multiplexed on-chip packet switched networks we consider worst-case delay bounds for Variable Bit-Rate (VBR) flows with aggregate scheduling, which schedules multiple flows as an aggregate flow. VBR Flows are characterized by a maximum transfer size, peak rate, burstiness, and average sustainable rate. Based on network calculus, we present and prove theorems to derive per-flow end-to-end Equivalent Service Curves (ESC) which are in turn used for computing Least Upper Delay Bounds (LUDBs) of individual flows. In a realistic case study we find that the end-to-end delay bound is up to 46.9% more accurate than the case without considering the traffic peak behavior. Likewise, results also show similar improvements for synthetic traffic patterns. The proposed methodology is implemented in C++ and has low run-time complexity, enabling quick evaluation for large and complex SoCs
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