822 research outputs found
Potential for improvement of population diet through reformulation of commonly eaten foods
Food reformulation: Reformulation of foods is considered one of the key options to achieve population nutrient goals. The compositions of many foods are modified to assist the consumer bring his or her daily diet more in line with dietary recommendations. Initiatives on food reformulation: Over the past few years the number of reformulated foods introduced on the European market has increased enormously and it is expected that this trend will continue for the coming years. Limits to food reformulation: Limitations to food reformulation in terms of choice of foods appropriate for reformulation and level of feasible reformulation relate mainly to consumer acceptance, safety aspects, technological challenges and food legislation. Impact on key nutrient intake and health: The potential impact of reformulated foods on key nutrient intake and health is obvious. Evaluation of the actual impact requires not only regular food consumption surveys, but also regular updates of the food composition table including the compositions of newly launched reformulated foods
The impact of supply chain-related factors on the environmental performance of manufacturing firms in Turkey
This paper investigates the impact of supply chain-related factors on the adoption of proactive environmental strategies, and the impact of such strategies on environmental investments and environmental performance. Data were collected from 96 Turkish manufacturers using an online questionnaire. The model was tested with PLS, a structural equation modelling method. The results show that a proactive environmental strategy leads to higher environmental investments which in turn lead to higher environmental performance. The results also show that two supply chain-related factors, organizational commitment and collaboration with suppliers, positively impact proactivity, whereas customer pressure does not have any significant direct impact on proactivity but it does positively impact environmental investments
The benefits of joint and separable financial management of couples
Financial management differs across households and this has various consequences for the financial outcomes and well-being of partners in households. A study has been performed on the financial management of couples, in households with or without children, in which data from both partners was collected on having joint and separate bank accounts, syncratic (joint) and autonomic (separate) financial management, the drivers of financial management, and the occurrence of financial problems. Based on the data, four financial management styles were distinguished: syncratic/joint, maledominant, female-dominant, and autonomic financial management styles. In the syncratic financial management style, partners have a joint bank account and take most financial decisions together. In the male/female-dominant decision styles, one partner (either husband or wife) takes the main decisions about how to spend from the joint bank account. In the autonomic money-management style, both partners have their own bank accounts, and can make their own decisions. As a conclusion, we find that both syncratic money management and having a joint instead of separate bank accounts correlate with fewer financial problems compared to male-dominant money management and having separate bank accounts. Working together as partners of a couple is beneficial for financial management and for avoiding financial problems
Big Data Health Care Innovations:Performance Dashboarding as a Process of Collective Sensemaking
Big data is poised to revolutionize health care, and performance dashboards can be an important tool to manage big data innovations. Dashboards show the progress being made and provide critical management information about effectiveness and efficiency. However, performance dashboards are more than just a clear and straightforward representation of performance in the health care context. Instead, the development and maintenance of informative dashboards can be more productively viewed as an interactive and iterative process involving all stakeholders. We refer to this process as dashboarding and reflect on our learnings within a large European Union–funded project. Within this project, multiple big data applications in health care are being developed, piloted, and scaled up. In this paper, we discuss the ways in which we cope with the inherent sensitivities and tensions surrounding dashboarding in such a dynamic environment. INTERNATIONAL REGISTERED REPORT IDENTIFIER (IRRID): RR2-10.2196/1677
The Electronic and Superconducting Properties of Oxygen-Ordered MgB2 compounds of the form Mg2B3Ox
Possible candidates for the Mg2B3Ox nanostructures observed in bulk of
polycrystalline MgB2 (Ref.1) have been studied using a combination of
Z-contrast imaging, electron energy loss spectroscopy (EELS) and
first-principles calculations. The electronic structures, phonon modes, and
electron phonon coupling parameters are calculated for two oxygen-ordered MgB2
compounds of composition Mg2B3O and Mg2B3O2, and compared with those of MgB2.
We find that the density of states for both Mg2B3Ox structures show very good
agreement with EELS, indicating that they are excellent candidates to explain
the observed coherent oxygen precipitates. Incorporation of oxygen reduces the
transition temperature and gives calculated TC values of 18.3 K and 1.6 K for
Mg2B3O and Mg2B3O2, respectively.Comment: Submitted to PR
Total knee arthroplasty after high tibial osteotomy. A systematic review
Background: Previous osteotomy may compromise subsequent knee replacement, but no guidelines considering knee arthroplasty after prior osteotomy have been developed. We describe a systematic review of non-randomized studies to analyze the effect of high tibial osteotomy on total knee arthroplasty. Methods: A computerized search for relevant studies published up to September 2007 was performed in Medline and Embase using a search strategy that is highly sensitive to find nonrandomized studies. Included were observational studies in which patients had total knee arthroplasty performed after prior high tibial osteotomy. Studies that fulfilled these criteria, were assessed for methodologic quality by two independent reviewers using the critical appraisal of observational studies developed by Deeks and the MINORS instrument. The study characteristics and data on the intervention, follow-up, and outcome measures, were extracted using a pre-tested standardized form. Primary outcomes were: knee range of motion, knee clinical score, and revision surgery. The grade of evidence was determined using the guidelines of the GRADE working group. Results: Of the 458 articles identified using our search strategy, 17 met the inclusion criteria. Fifteen studies were cohort study with a concurrent control group, one was a historical cohort study and one a case-control study. Nine studies scored 50% or more on both methodological quality assessments. Pooling of the results was not possible due to the heterogeneity of the studies, and our analysis could not raise the overall low quality of evidence. No significant differences between primary total knee arthroplasty and total knee arthroplasty after osteotomy were found for knee range of motion in four out of six studies, knee clinical scores in eight out of nine studies, and revision surgery in eight out of eight studies after a median follow-up of 5 years. Conclusion: Our analysis suggests that osteotomy does not compromise subsequent knee replacement. However, the low quality of evidence precludes solid clinical conclusions.</p
Total knee arthroplasty after high tibial osteotomy. A systematic review
Background: Previous osteotomy may compromise subsequent knee replacement, but no guidelines considering knee arthroplasty after prior osteotomy have been developed. We describe a systematic review of non-randomized studies to analyze the effect of high tibial osteotomy on total knee arthroplasty. Methods: A computerized search for relevant studies published up to September 2007 was performed in Medline and Embase using a search strategy that is highly sensitive to find nonrandomized studies. Included were observational studies in which patients had total knee arthroplasty performed after prior high tibial osteotomy. Studies that fulfilled these criteria, were assessed for methodologic quality by two independent reviewers using the critical appraisal of observational studies developed by Deeks and the MINORS instrument. The study characteristics and data on the intervention, follow-up, and outcome measures, were extracted using a pre-tested standardized form. Primary outcomes were: knee range of motion, knee clinical score, and revision surgery. The grade of evidence was determined using the guidelines of the GRADE working group. Results: Of the 458 articles identified using our search strategy, 17 met the inclusion criteria. Fifteen studies were cohort study with a concurrent control group, one was a historical cohort study and one a case-control study. Nine studies scored 50% or more on both methodological quality assessments. Pooling of the results was not possible due to the heterogeneity of the studies, and our analysis could not raise the overall low quality of evidence. No significant differences between primary total knee arthroplasty and total knee arthroplasty after osteotomy were found for knee range of motion in four out of six studies, knee clinical scores in eight out of nine studies, and revision surgery in eight out of eight studies after a median follow-up of 5 years. Conclusion: Our analysis suggests that osteotomy does not compromise subsequent knee replacement. However, the low quality of evidence precludes solid clinical conclusions.</p
Total knee arthroplasty after high tibial osteotomy. A systematic review
Background: Previous osteotomy may compromise subsequent knee replacement, but no guidelines considering knee arthroplasty after prior osteotomy have been developed. We describe a systematic review of non-randomized studies to analyze the effect of high tibial osteotomy on total knee arthroplasty. Methods: A computerized search for relevant studies published up to September 2007 was performed in Medline and Embase using a search strategy that is highly sensitive to find nonrandomized studies. Included were observational studies in which patients had total knee arthroplasty performed after prior high tibial osteotomy. Studies that fulfilled these criteria, were assessed for methodologic quality by two independent reviewers using the critical appraisal of observational studies developed by Deeks and the MINORS instrument. The study characteristics and data on the intervention, follow-up, and outcome measures, were extracted using a pre-tested standardized form. Primary outcomes were: knee range of motion, knee clinical score, and revision surgery. The grade of evidence was determined using the guidelines of the GRADE working group. Results: Of the 458 articles identified using our search strategy, 17 met the inclusion criteria. Fifteen studies were cohort study with a concurrent control group, one was a historical cohort study and one a case-control study. Nine studies scored 50% or more on both methodological quality assessments. Pooling of the results was not possible due to the heterogeneity of the studies, and our analysis could not raise the overall low quality of evidence. No significant differences between primary total knee arthroplasty and total knee arthroplasty after osteotomy were found for knee range of motion in four out of six studies, knee clinical scores in eight out of nine studies, and revision surgery in eight out of eight studies after a median follow-up of 5 years. Conclusion: Our analysis suggests that osteotomy does not compromise subsequent knee replacement. However, the low quality of evidence precludes solid clinical conclusions
Effect of dietary fat supplementation during late pregnancy and first six months of lactation on maternal and infant vitamin A status in rural Bangladesh
Dietary fat intake is extremely low in most communities with vitamin A
deficiency. However, its role in vitamin A status of pregnant and
lactating women is poorly understood. The aim of the study was to
examine the effect of supplementing women with fat from mid-/late
pregnancy until six months postpartum on their vitamin A status and
that of their infants. Women recruited at 5-7 months of gestation were
supple-mented daily with 20 mL of soybean-oil (n=248) until six months
postpartum or received no supplement (n=251). Dietary fat intake was
assessed by 24-hour dietary recall at enrollment and at 1, 3 and 6
months postpartum. Concentrations of maternal plasma retinol,
\u3b2-carotene, and lutein were measured at enroll-ment and at 1, 3
and 6 months postpartum, and those of infants at six months postpartum.
Concentration of breastmilk retinol was measured at 1, 3 and 6 months
postpartum. The change in concentration of plasma retinol at three
months postpartum compared to pregnancy was significantly higher in the
supple-mented compared to the control women (+0.04 vs -0.07 \u3bcmol/L
respectively; p<0.05). Concentrations of plasma \u3b2-carotene and
lutein declined in both the groups during the postpartum period but the
decline was significantly less in the supplemented than in the control
women at one month \u3b2-carotene -0.07 vs -0.13 \u3bcmol/L,
p<0.05); lutein -0.26 vs -0.49 \u3bcmol/L, p<0.05) and three
months \u3b2-carotene -0.04 vs -0.08 \u3bcmol/L, p<0.05; lutein
-0.31 vs -0.47 \u3bcmol/L, p<0.05). Concentration of breastmilk
retinol was also signifi-cantly greater in the supplemented group at
three months postpartum than in the controls (0.68\ub10.35 vs
0.55\ub10.34 \u3bcmol/L respectively, p<0.03). Concentrations of
infants\u2032 plasma retinol, \u3b2-carotene, and lutein, measured at
six months of age, did not differ between the groups. Fat
supplementation during pregnancy and lactation in women with a very low
intake of dietary fat has beneficial effects on maternal postpartum
vitamin A status
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