Investigation of the surface structure and activity of molybdenum oxide-containing catalysts : I. An infrared study of the surface structure of molybdena-alumina catalysts

A comparison has been made of the infrared spectra of alumina with molybdenum oxide-alumina in both the oxidized and reduced forms. In the case of molybdena-alumina prepared via adsorption of gaseous MoO2(OH)2, the spectra show that a practically complete monolayer of Mo6+ oxide covers the alumina. After reduction with hydrogen the hydroxyls of the carrier appear. From the reversibility of reduction and oxidation under mild conditions it has been established that the reduced oxide is present as an interrupted monolayer

Pharmacokinetics of vibunazole (Bay n7133) administered orally to healthy subjects

Contains fulltext : 4447.pdf (publisher's version ) (Open Access

Using State-of-the-art Emotion Detection Models in a Crisis Communication Context

Times of crisis are usually associated with highly emotional experiences, which often result in emotionally charged communication. This is especially the case on social media. Identifying the emotional climate on social media is imperative in the context of crisis communication, e.g., in view of shaping crisis response strategies. However, the sheer volume of social media data often makes manual oversight impossible. In this paper, we therefore investigate how automatic methods for emotion detection can aid research on crisis communication and social media. Concretely, we investigate two Dutch emotion detection models (a transformer model and a classical machine learning model based on dictionaries) and apply them to Dutch tweets about four different crisis cases. First, we perform a validation study to assess the performance of these models in the domain of crisis-related tweets. Secondly, we propose a framework for monitoring the emotional climate on social media, and assess whether emotion detection models can be used to address the steps in the framework

Minder mineralenverlies in de substraatteelt : een economische analyse van opties

De overheid wil stapsgewijs de lozingen van mineralen door glastuinbouwbedrijven met substraatteelt naar de omgeving terugdringen. In 2027 moeten deze lozingen vrijwel nul zijn. Onderzocht is welke maatregelen daartoe door de bedrijven genomen kunnen worden en welke kosten die met zich mee zullen brengen. The Dutch government wants to reduce the release (leaching) of nutrients from greenhouse horticultural firms with substrate-grown crops into the environment. These releases must be practically nil in 2027. This study examined which measures could be taken by the firms to comply with this objective and the associated costs

Long-term second primary cancer risk in adolescent and young adult (15-39 years) cancer survivors:a population-based study in the Netherlands between 1989 and 2018

Background: Few studies have comprehensively investigated the long-term second cancer risk among adolescent and young adult (AYA, aged 15-39 years) cancer survivors. This study investigated the long-term second cancer risk by including the full range of first and second cancer combinations with at least 10 observations in the Netherlands between 1989 and 2018. Materials and methods: First and second primary cancer data of all 6-month AYA cancer survivors were obtained from the nationwide population-based Netherlands Cancer Registry. Excess cancer risk compared to the general population was assessed with standardized incidence ratio (SIR) and absolute excess risk (AER) statistics up to 25 years after diagnosis. Cumulative incidences were estimated, using death as a competing risk factor. Analyses were carried out with and without applying multiple cancer rules. Results: The cohort included 99 502 AYA cancer survivors. Male survivors had a 2-fold higher risk of developing any cancer compared to the general population, whereas this was around 1.3-fold in females. AERs were 17.5 and 10.1 per 10 000 person-years for males and females. The long-term excess risk of cancer was significantly higher for most first and second primary cancer combinations, but comparable and lower risk estimates were also observed. Application of the multiple cancer rules resulted in a noticeable risk underestimation in melanoma, testicular, and breast cancer survivors. Risk outcomes remained similar in most cases otherwise. The cumulative incidence of second cancer overall increased over time up to 8.9% in males and 10.3% in females at 25 years’ follow-up. Highest long-term cumulative incidences were observed among lymphoma survivors (13.3% males and 18.9% females). Conclusions: AYA cancer survivors have a higher cancer risk compared to the general population for most cancers up to 25 years after their initial cancer diagnosis. Additional studies that investigate risk factors for the specific cancer type combinations are needed to develop personalized follow-up strategies.</p

Long-term second primary cancer risk in adolescent and young adult (15-39 years) cancer survivors:a population-based study in the Netherlands between 1989 and 2018

Background: Few studies have comprehensively investigated the long-term second cancer risk among adolescent and young adult (AYA, aged 15-39 years) cancer survivors. This study investigated the long-term second cancer risk by including the full range of first and second cancer combinations with at least 10 observations in the Netherlands between 1989 and 2018. Materials and methods: First and second primary cancer data of all 6-month AYA cancer survivors were obtained from the nationwide population-based Netherlands Cancer Registry. Excess cancer risk compared to the general population was assessed with standardized incidence ratio (SIR) and absolute excess risk (AER) statistics up to 25 years after diagnosis. Cumulative incidences were estimated, using death as a competing risk factor. Analyses were carried out with and without applying multiple cancer rules. Results: The cohort included 99 502 AYA cancer survivors. Male survivors had a 2-fold higher risk of developing any cancer compared to the general population, whereas this was around 1.3-fold in females. AERs were 17.5 and 10.1 per 10 000 person-years for males and females. The long-term excess risk of cancer was significantly higher for most first and second primary cancer combinations, but comparable and lower risk estimates were also observed. Application of the multiple cancer rules resulted in a noticeable risk underestimation in melanoma, testicular, and breast cancer survivors. Risk outcomes remained similar in most cases otherwise. The cumulative incidence of second cancer overall increased over time up to 8.9% in males and 10.3% in females at 25 years’ follow-up. Highest long-term cumulative incidences were observed among lymphoma survivors (13.3% males and 18.9% females). Conclusions: AYA cancer survivors have a higher cancer risk compared to the general population for most cancers up to 25 years after their initial cancer diagnosis. Additional studies that investigate risk factors for the specific cancer type combinations are needed to develop personalized follow-up strategies.</p