Organizing reflexivity in designed change: The ethnoventionist approach

Purpose – The purpose of this paper is to reflect upon the role of intervention/oriented scientists in the process of organisation development. The paper seeks to contribute to the growing interest in design studies for organisation development and argues that a focus on reflexivity is missing in current debate. The aim of the paper to develop critical reflexiveness for organization design studies by introducing the ethnoventionist approach. Design/methodology/approach – The paper discusses the ideal forms of clinical inquiry, participative action research, ethnography, and the ethnoventionist approach. The ethnoventionist approach is described by its central aspects: a focus on reflexivity, a management (but not managerialist) orientation, commitment to obtaining a deep understanding, connecting the multi/layered context, and studying in pre/arranged longitudinal intervals. Findings – The ethnoventionist approach uses organisational ethnographies to facilitate intervention strategies intended to improve organisations. An example of such an approach in the design of new collaborative practices in the Dutch construction sector is drawn on. Practical implications – The essence of the ethnoventionist approach is to obtain a deeper understanding of organisational change. The ethnoventionist approach helps to overcome a lack of attention to management in current ethnographic bodies of knowledge and to deepen existing management approaches to change dynamics. Ethnoventionist approaches can be very useful for intervention/oriented studies of change processes which require high levels of engagement and which produce high/quality ethnographic data. Originality/value – This paper explores a new research approach that has not been discussed previously. © 2010, Emerald Group Publishing Limite

PRUSSIC I - a JVLA survey of HCN/HCO+/HNC (1-0) emission in z∼\sim3 dusty galaxies: Low dense-gas fractions in high-redshift star-forming galaxies

Dusty star-forming galaxies (DSFGs) at redshift z$\geq$1 are among the most vigorously star-forming galaxies in the Universe. However, their dense ($\geq$10$^5$ cm$^{-3}$ ) gas phase - typically traced by HCN(1-0) - remains almost entirely unexplored: only two DSFGs have been detected in HCN(1-0) to date. We present results of a JVLA survey of the J=1-0 transition of HCN, HCO+, and HNC(1-0) in six strongly lensed DSFGs at z = 2.5 - 3.3, effectively doubling the number of DSFGs with deep observations of these lines. We detect HCN(1-0) emission in one source (J1202+5354, 4.4$\sigma$), with a tentative HCO+ (1-0) detection in another (J1609+6045, 3.3$\sigma$). Spectral stacking yields strict upper limits on the HCN/FIR ($\leq$3.6$\times$10$^{-4}$) and HCN/CO(1-0) ratios ($\leq$0.045). The inferred HCN/FIR ratios (a proxy for the star-formation efficiency) are consistent with those in z$\sim$0 FIR-luminous starbursts. However, the HCN/CO ratios - a proxy for the dense-gas fraction - are a factor of a few lower than suggested by the two previous DSFG detections. Our results imply that most DSFGs have low dense-gas fractions. A comparison with Krumholz & Thompson (2007) models of star-forming galaxies indicates that the bulk of gas in DSFGs is at lower densities ($\approx$10$^2$ cm$^{-3}$ ), similar to "normal" star-forming galaxies, rather than ultraluminous starbursts.Comment: Submitted to A&A 28th April 2022, accepted 19th July 202

PRUSSIC II -- ALMA imaging of dense-gas tracers in SDP.81: Evidence for low mechanical heating and a sub-solar metallicity in a z=3.04 dusty galaxy

We present deep ALMA Band 3 observations of the HCN, HCO+, and HNC (4-3) emission in SDP.81, a well-studied z = 3.042 strongly lensed galaxy. These lines trace the high-density gas, which remains almost entirely unexplored in z$\geq$1 galaxies. Additionally, these dense-gas tracers are potentially powerful diagnostics of the mechanical heating of the interstellar medium. While the HCN(4-3) and HNC(4-3) lines are not detected, the HCO+(4-3) emission is clearly detected and resolved. This is the third detection of this line in a high-redshift star-forming galaxy. We find an unusually high HCO+/HCN intensity ratio of $\geq$2.2. Based on the photodissociation region modelling, the most likely explanation for the elevated HCO+/HCN ratio is that SDP.81 has low mechanical heating - less than 10% of the total energy budget - and a sub-solar metallicity, Z=0.5 Z$_\odot$. While such conditions might not be representative of the general population of high-redshift dusty galaxies, lower-than-solar metallicity might have a significant impact on gas masses inferred from CO observations. In addition, we report the detection of CO(0-1) absorption from the foreground lensing galaxy and CO(1-0) emission from a massive companion to the lensing galaxy, approximately 50 kpc to the southeast.Comment: A&A accepted, in press. 10 pages, 10 figure

Using CT colonography as a triage technique after a positive faecal occult blood test in colorectal cancer screening

Item does not contain fulltextOBJECTIVE: The purpose of this study was to evaluate the effectiveness of CT colonography (CTC) as a triage technique in faecal occult blood test (FOBT)-positive screening participants. METHODS: Consecutive guaiac (G-FOBT) and immunochemical (I-FOBT) FOBT-positive patients scheduled for colonoscopy underwent CTC with iodine tagging bowel preparation. Each CTC was read independently by two experienced observers. Per patient sensitivity, specificity and positive and negative predictive values (PPV and NPV) were calculated based on double reading with different CTC cut-off lesion sizes using segmental unblinded colonoscopy as the reference standard. The acceptability of the technique to patients was evaluated with questionnaires. RESULTS: 302 FOBT-positive patients were included (54 G-FOBT and 248 I-FOBT). 22 FOBT-positive patients (7%) had a colorectal carcinoma and 211 (70%) had a lesion >or=6 mm. Participants considered colonoscopy more burdensome than CTC (por=6 mm. The PPV of CTC was 87% (95% CI 80% to 93%) and NPV 77% (95% CI 69% to 85%). Using CTC as a triage technique in 100 FOBT-positive patients would mean that colonoscopy could be prevented in 28 patients while missing >or=10 mm lesions in 2 patients. CONCLUSION: CTC with limited bowel preparation has reasonable predictive values in an FOBT-positive population and a higher acceptability to patients than colonoscopy. However, due to the high prevalence of clinically relevant lesions in FOBT-positive patients, CTC is unlikely to be an efficient triage technique in a first round FOBT population screening programme

The sweet spot in sustainability: a framework for corporate assessment in sugar manufacturing

The assessment of corporate sustainability has become an increasingly important topic, both within academia and in industry. For manufacturing companies to conform to their commitments to sustainable development, a standard and reliable measurement framework is required. There is, however, a lack of sector-specific and empirical research in many areas, including the sugar industry. This paper presents an empirically developed framework for the assessment of corporate sustainability within the Thai sugar industry. Multiple case studies were conducted, and a survey using questionnaires was also employed to enhance the power of generalisation. The developed framework is an accurate and reliable measurement instrument of corporate sustainability, and guidelines to assess qualitative criteria are put forward. The proposed framework can be used for a company’s self-assessment and for guiding practitioners in performance improvement and policy decision-maki

Campylobacter jejuni Translocation across Intestinal Epithelial Cells Is Facilitated by Ganglioside-Like Lipooligosaccharide Structures

Translocation across intestinal epithelial cells is an established pathogenic feature of the zoonotic bacterial species Campylobacter jejuni. The number of C. jejuni virulence factors known to be involved in translocation is limited. In the present study, we investigated whether sialylation of C. jejuni lipooligosaccharide (LOS) structures, generating human nerve ganglioside mimics, is important for intestinal epithelial translocation. We here show that C. jejuni isolates expressing ganglioside-like LOS bound in larger numbers to the Caco-2 intestinal epithelial cells than C. jejuni isolates lacking such structures. Next, we found that ganglioside-like LOS facilitated endocytosis of bacteria into Caco-2 cells, as visualized by quantitative microscopy using the early and late endosomal markers early endosome-associated protein 1 (EEA1), Rab5, and lysosome-associated membrane protein 1 (LAMP-1). This increased endocytosis was associated with larger numbers of surviving and translocating bacteria. Next, we found that two different intestinal epithelial cell lines (Caco-2 and T84) responded with an elevated secretion of the T-cell attractant CXCL10 to infection by ganglioside-like LOS-expressing C. jejuni isolates. We conclude that C. jejuni translocation across Caco-2 cells is facilitated by ganglioside-like LOS, which is of clinical relevance since C. jejuni ganglioside-like LOS-expressing isolates are linked with severe gastroenteritis and bloody stools in C. jejuni-infected patients

The Paradox of Power in CSR: A Case Study on Implementation

Purpose Although current literature assumes positive outcomes for stakeholders resulting from an increase in power associated with CSR, this research suggests that this increase can lead to conflict within organizations, resulting in almost complete inactivity on CSR. Methods A single in-depth case study, focusing on power as an embedded concept. Results Empirical evidence is used to demonstrate how some actors use CSR to improve their own positions within an organization. Resource dependence theory is used to highlight why this may be a more significant concern for CSR. Conclusions Increasing power for CSR has the potential to offer actors associated with it increased personal power, and thus can attract opportunistic actors with little interest in realizing the benefits of CSR for the company and its stakeholders. Thus power can be an impediment to furthering CSR strategy and activities at the individual and organizational level