Extraversion is linked to volume of the orbitofrontal cortex and amygdala

Contains fulltext : 103145.pdf (publisher's version ) (Open Access)Neuroticism and extraversion are personality factors associated with the vulnerability for developing depression and anxiety disorders, and are possibly differentially related to brain structures implicated in the processing of emotional information and the generation of mood states. To date, studies on brain morphology mainly focused on neuroticism, a dimension primarily related to negative affect, yielding conflicting findings concerning the association with personality, partially due to methodological issues and variable population samples under study. Recently, extraversion, a dimension primarily related to positive affect, has been repeatedly inversely related to with symptoms of depression and anxiety disorders. In the present study, high resolution structural T1-weighted MR images of 65 healthy adults were processed using an optimized Voxel Based Morphometry (VBM) approach. Multiple regression analyses were performed to test for associations of neuroticism and extraversion with prefrontal and subcortical volumes. Orbitofrontal and right amygdala volume were both positively related to extraversion. Extraversion was differentially related to volume of the anterior cingulate cortex in males (positive) and females (negative). Neuroticism scores did not significantly correlate with these brain regions. As extraversion is regarded a protective factor for developing anxiety disorders and depression and has been related to the generation of positive affect, the present results indicate that the reduced likelihood of developing affective disorders in individuals high on extraversion is related to modulation of emotion processing through the orbitofrontal cortex and the amygdala.6 p

Histologisch onderzoek van de plamacellulaire reactie en zijn plaats in de histophysiologie van de lymphklier

Het onderzoek waarvan in dit proefschrift verslag wordt uitgebracht, betreft voornamelijk de histologie van de antilichaamvorming in delymphklier. Daarbij zijn een aantal gegevens verkregen die niet alleen het inzicht verdiepen in de processen, welke zich in verband met deze antilichaamvorming in de lymphklier afspelen, maar die ook een geheel andere beoordeling mogelijk maken van de overige functies van de lymphklier met name van de lymphocytopoiese..... Zie: Samenvatting

Seismic stratigraphy of the Lower Cretaceous Valhall Formation (Danish Graben, North Sea)

Detailed seismic stratigraphic analysis of a 3D seismic survey covering the southern part of the Danish Central Graben in the North Sea has revealed a complex stratigraphic basin infill pattern controlled by eustacy and local tectonics in the Lower Cretaceous Valhall Formation. The understanding of the stratigraphic architecture of this mudstone formation is critical for the development of the overlaying chalk reservoirs of the Tuxen and Sola Formations. The applied workflow included an application of flattening in order to approximate the Lower Cretaceous basin morphology, the attenuation of multiples generated by the overlying chalk deposits, a systematic use of both 2D transects and horizon slices in the analysis of the depositional geometries and the application of a Relative Geological Time (RGT) model interpretation technology. The results show an asymmetrical infill of the Lower Cretaceous consisting of westward prograding, mud-dominated clinoforms. The overall progradational pattern is clearly expressed in the most southern part of the basin by coast-parallel features interpreted as shelf margin breaks. The asymmetrical paleotopography, created by the muddy shelf of the Valhall Formation, formed subsequently the substratum for the deposition of the chalks of the Tuxen and Sola Formations, and controlled their facies distribution

Modélisation stratigraphique de la distribution et de la préservation de la matière organique en milieu marin profond

Afin de développer une modélisation stratigraphique de la distribution et de la préservation de la matière organique en milieu marin, trois modèles ont été utilisés et adaptés : DIONISOS, modèle stratigraphique, ROMS, modèle physique et NPZD, modèle biogéochimique. L'intérêt de la méthodologie est de prendre en compte l'ensemble des processus contrôlant le cycle de la matière organique depuis sa production à la surface de l'océan jusqu'à son enfouissement dans les sédiments. Après avoir calibré et testé la sensibilité des 3 modèles, des simulations ont été réalisées afin de reproduire la sédimentation biogénique sur la marge Namibienne (Afrique du Sud Ouest). Grâce à la base de données disponible sur ce système d'upwelling, les paramètres ont été déterminés et ont permisd'exprimer les principaux facteurs de contrôle tels que l'intensité de l'upwelling, les conditions trophiques du milieu, la morphologie de la marge, l'eustatisme, etc. De plus, les résultats comparés aux données réelles ont montré que la modélisation reproduisait correctement l'influence de la variabilité climatique de ces facteurs sur l'accumulation de matière organique dans les sédiments d'une marge continentale passive.BORDEAUX1-BU Sciences-Talence (335222101) / SudocSudocFranceF

Mut Basin, Turkey: Miocene carbonate depositional styles and mixed systems in an icehouse setting

WOS: 000396839300013The Mut Basin in southcentral Turkey contains a rich variety of Cenozoic carbonate deposits that developed on a complex preMiocene topography and can be studied in seismic-scale, threedimensional outcrops. These include open and rimmed carbonate shelves with steep slopes, small isolated platforms, and mixed carbonate-siliciclastic systems showing reciprocal sedimentation. The exceptional preservations of the stratal geometries make it possible to easily link large-scale depositional geometry to depositional facies in a variety of platform types and depositional environments. The Mut Basin provides a better understanding of (1) the control of antecedent topography on carbonate platform development, (2) the influence of icehouse conditions (e.g., highamplitude, high-frequency sea level fluctuations) on the carbonate system, (3) the link between faunal evolution and the style of carbonate platforms and stratigraphic architecture, (4) lateral and reciprocal carbonate and siliciclastic sedimentation, (5) platform asymmetry and local controls on stratal geometries, and (6) the architecture of steep carbonate margin and associated gravitational collapse deposits. These concepts are directly applicable to time-equivalent Cenozoic carbonate reservoir systems in Southeast Asia, the southern Caribbean, and the eastern Mediterranean