Integrating accessibility and functional requirements

Initial research on Web accessibility was focused on testing completed Web pages. More recently, the focus is moving to integrating accessibility features into coding tools such as Dreamweaver 8 and plugins notably LIFT. Thus accessibility is being considered slightly earlier in the development process. However, the state of Web accessibility is still disappointing even on websites that have followed the guidelines and or used evaluation and coding tools. We are proposing an approach to start considering accessibility much earlier. Our purpose is to address accessibility in the context of what is to be done and who will be participating. In this paper, we present views of Web developers about this approach. We then show (using a case study) how Web developers can elicit accessibility requirements alongside functional requirements and integrate the two to obtain conceptual models with explicit traces of accessibility requirements integrated with functional requirements. Finally we discuss lessons learnt from the case study and common benefits of the approach for Web accessibility and Web projects

A framework for filtering web accessibility guidelines

This paper first presents a framework for filtering the Web Accessibility Guidelines according to contexts of use. It then presents a prototype that implements the framework and explains an evaluation of the prototype

Best practices for operating underwater gliders in Atlantic Canada

Ocean gliders are versatile tools for making ocean observations. This paper summarizes the experience, of nearly two decades, of glider observing activity in Atlantic Canada. It reviews key considerations for operating gliders based on the experience and the lessons learned. This paper has three main goals: 1. To provide new and emerging glider users with guidance and considerations for developing a glider program. 2. Review the literature on sensor development for gliders and the use of gliders. 3. To highlight different mission scenarios that include enough practical considerations to support operating gliders. The use of gliders is rapidly expanding, but the documentation and consolidation of best practices for their operational use in Atlantic Canada remains underdeveloped. This summary provides a guide that should be helpful both to new and experienced glider operators and potential users, to observe the oceanography of this region and addresses regional challenges. We believe documenting our experience will be also helpful to the global glider community. We summarize the most critical considerations of utilizing gliders. We review the issues specific to the platform use and concerns about how to optimize the use of key sensors to contribute to an oceanographic observing program

What clinicians who practice in countries reaching malaria elimination should be aware of: lessons learnt from recent experience in Sri Lanka

Following progressive reduction in confirmed cases of malaria from 2002 to 2007 (41,411 cases in 2002, 10,510 cases in 2003, 3,720 cases in 2004, 1,640 cases in 2005, 591 cases in 2006, and 198 cases in 2007). Sri Lanka entered the pre-elimination stage of malaria in 2008. One case of indigenous malaria and four other cases of imported malaria are highlighted here, as the only patients who presented to the Professorial Medical Unit, Colombo North Teaching Hospital, Ragama, Sri Lanka over the past eight years, in contrast to treating several patients a week about a decade ago. Therefore, at the eve of elimination of malaria from Sri Lanka, it is likely that the infection is mostly encountered among travellers who return from endemic areas, or among the military who serve in un-cleared areas of Northern Sri Lanka. They may act as potential sources of introducing malaria as until malaria eradication is carried out. These cases highlight that change in the symptomatology, forgetfulness regarding malaria as a cause of acute febrile illness and deterioration of the competency of microscopists as a consequence of the low disease incidence, which are all likely to contribute to the delay in the diagnosis. The importance regarding awareness of new malaria treatment regimens, treatment under direct observation, prompt notification of suspected or diagnosed cases of malaria and avoiding blind use of anti-malarials are among the other responsibilities expected of all clinicians who manage patients in countries reaching malaria elimination

Standing genetic diversity and selection at functional gene loci are associated with differential invasion success in two non‐native fish species

Invasive species are expected to experience a unique combination of high genetic drift due to demographic factors while also experiencing strong selective pressures. The paradigm that reduced genetic diversity should limit the evolutionary potential of invasive species and thus their potential for range expansion has received little empirical support, possibly due to the choice of genetic markers. Our goal was to test for effects of genetic drift and selection at functional genetic markers as they relate to the invasion success of two paired invasive goby species, one widespread (successful) and one with limited range expansion (less successful). We genotyped fish using two marker types: single nucleotide polymorphisms (SNPs) in known-function, protein-coding genes and microsatellites to contrast the effects of neutral genetic processes. We identified reduced allelic variation in the invaded range for the less-successful tubenose goby. SNPs putatively under selection were responsible for the observed differences in population structure between marker types for round goby (successful) but not tubenose goby (less successful). A higher proportion of functional loci experienced divergent selection for round goby, suggesting increased evolutionary potential in invaded ranges may be associated with round goby’s greater invasion success. Genes involved in thermal tolerance were divergent for round goby populations but not tubenose goby, consistent with the hypothesis that invasion success for fish in temperate regions is influenced by capacity for thermal tolerance. Our results highlight the need to incorporate functional genetic markers in studies to better assess evolutionary potential for the improved conservation and management of species

What the radiologist needs to know about the diabetic patient

Diabetes mellitus (DM) is recognised as a major health problem. Ninety-nine percent of diabetics suffer from type 2 DM and 10% from type 1 and other types of DM. The number of diabetic patients worldwide is expected to reach 380 millions over the next 15 years. The duration of diabetes is an important factor in the pathogenesis of complications, but other factors frequently coexisting with type 2 DM, such as hypertension, obesity and dyslipidaemia, also contribute to the development of diabetic angiopathy. Microvascular complications include retinopathy, nephropathy and neuropathy. Macroangiopathy mainly affects coronary arteries, carotid arteries and arteries of the lower extremities. Eighty percent of deaths in the diabetic population result from cardiovascular incidents. DM is considered an equivalent of coronary heart disease (CHD). Stroke and peripheral artery disease (PAD) are other main manifestations of diabetic macroangiopathy. Diabetic cardiomyopathy (DC) represents another chronic complication that occurs independently of CHD and hypertension. The greater susceptibility of diabetic patients to infections completes the spectrum of the main consequences of DM. The serious complications of DM make it essential for physicians to be aware of the screening guidelines, allowing for earlier patient diagnosis and treatment

Health – related quality of life of Kuwaiti women with breast cancer: a comparative study using the EORTC Quality of Life Questionnaire

<p>Abstract</p> <p>Background</p> <p>The Kuwaiti perspective on quality of life (QOL) in breast cancer is important because it adds the contribution from a country where the disease affects women at a relatively younger age and seems to be more aggressive. We used the EORTC QLQ – C30 and its breast-specific module (BR-23) to highlight the health-related QOL of Kuwaiti women with breast cancer, in comparison with the international data, and assessed the socio-demographic and clinical variables that predict the five functional scales and global QOL (GQOL) scale of the QLQ – C30.</p> <p>Methods</p> <p>Participants were consecutive clinic attendees for chemotherapy, in stable condition, at the Kuwait Cancer Control Center.</p> <p>Results</p> <p>The 348 participants were aged 20–81 years (mean 48.3, SD 10.3); 58.7% had stages III and IV disease. Although the mean scores for QLQ – C30 (GQOL, 45.3; and five functional scales, 52.6%–61.2%) indicated that the patients had poor to average functioning, only 5.8% to 11.2% had scores that met the </= 33% criterion for problematic functioning, while 12.0% to 40.0% met the >66% criterion for more severe symptoms. Most (47.8%–70.1%) met the >66% criterion for "good functioning" on the BR-23 functional scales. The mean scores of the QLQ – C30 indicated that, despite institutional supports, Kuwaiti women had clinically significantly poorer global QOL and functional scale scores, and more intense symptom experience, in comparison with the international data (i.e., </= 10% difference between groups). For the BR-23, Kuwaiti women seemed to have clinically significantly better functional scale scores, but more severe symptoms, especially systemic side effects and breast symptoms. Younger women had poorer HRQOL scores. In regression analysis, social functioning accounted for the highest proportion of variance for GQOL.</p> <p>Conclusion</p> <p>The relatively high number that met the criterion for good functioning on the functional scales is an evidence base to boost national health education about psychosocial prognosis in cancer. In view of the poor performance on the symptom scales, clinicians treating Kuwaiti women with breast cancer should prepare them for the acute toxicities of treatment and address fatigue. The findings call for the institution of a psycho-oncology service to address psycho-social issues.</p

Crisis-induced disruptions in place-based social-ecological research ‐ an opportunity for redirection

Place-based research faces multiple threats, including both natural and global health hazards and political conflicts, which may disrupt fieldwork. The current COVID-19 pandemic shows how these threats can drastically affect social-ecological research activities given its engagement with different local stakeholders, disciplines, and knowledge systems. The crisis reveals the need for adaptive research designs while also providing an opportunity for a structural shift towards a more sustainable and inclusive research landscape

Crisis-induced disruptions in place-based social-ecological research ‐ an opportunity for redirection

Place-based research faces multiple threats, including both natural and global health hazards and political conflicts, which may disrupt fieldwork. The current COVID-19 pandemic shows how these threats can drastically affect social-ecological research activities given its engagement with different local stakeholders, disciplines, and knowledge systems. The crisis reveals the need for adaptive research designs while also providing an opportunity for a structural shift towards a more sustainable and inclusive research landscape