Doelmatigheidswinst van minder hypotheekrenteaftrek

We bespreken enkele welvaartsdividenden van het versoberen van de subsidie op de eigen woning. Deze dividenden doen zich in de eerste plaats voor op de woningmarkt. Daarnaast kan zich een welvaartsdividend voordoen op de arbeidsmarkt. De omvang van dit tweede dividend is evenwel sterk afhankelijk van de elasticiteit van het aanbod van woningen

Inhomogeneous Superconductivity in Comb-Shaped Josephson Junction Networks

We show that some of the Josephson couplings of junctions arranged to form an inhomogeneous network undergo a non-perturbative renormalization provided that the network's connectivity is pertinently chosen. As a result, the zero-voltage Josephson critical currents $I_c$ turn out to be enhanced along directions selected by the network's topology. This renormalization effect is possible only on graphs whose adjacency matrix admits an hidden spectrum (i.e. a set of localized states disappearing in the thermodynamic limit). We provide a theoretical and experimental study of this effect by comparing the superconducting behavior of a comb-shaped Josephson junction network and a linear chain made with the same junctions: we show that the Josephson critical currents of the junctions located on the comb's backbone are bigger than the ones of the junctions located on the chain. Our theoretical analysis, based on a discrete version of the Bogoliubov-de Gennes equation, leads to results which are in good quantitative agreement with experimental results.Comment: 4 pages, 2 figures, revte

The Changing Face of α Centauri B: Probing plage and stellar activity in K-dwarfs

A detailed knowledge of stellar activity is crucial for understanding stellar dynamos, as well as pushing exoplanet radial-velocity detection limits towards Earth analogue confirmation. We directly compare archival HARPS spectra taken at the minimum in $\alpha$ Cen B's activity cycle to a high-activity state when clear rotational modulation of $\log{R'_{HK}}$ is visible. Relative to the inactive spectra, we find a large number of narrow pseudo-emission features in the active spectra with strengths that are rotationally modulated. These features most likely originate from plage, spots, or a combination of both. They also display radial velocity variations of $\sim$300 m s$^{-1}$ - consistent with an active region rotating across the stellar surface. Furthermore, we see evidence that some of the lines originating from the `active immaculate' photosphere appear broader relative to the `inactive immaculate' case. This may be due to enhanced contributions of e.g. magnetic bright points to these lines, which then causes additional line broadening. More detailed analysis may enable measurements of plage and spot coverage using single spectra in the future.Comment: 6 pages, 4 figures, accepted for publication in Monthly Notices of the Royal Astronomical Society (MNRAS) Letter

The size of macroscopic superposition states in flux qubits

The question as to whether or not quantum mechanics is applicable to the macroscopic scale has motivated efforts to generate superposition states of macroscopic numbers of particles and to determine their effective size. Superpositions of circulating current states in flux qubits constitute candidate states that have been argued to be at least mesoscopic. We present a microscopic analysis that reveals the number of electrons participating in these superpositions to be surprisingly but not trivially small, even though differences in macroscopic observables are large.Comment: 7 pages, no figure

Does affirming children's autonomy and prosocial intentions help? A microtrial into intervention component effects to improve psychosocial behavior

Item does not contain fulltextPrior research has related children's prosocial behavior to overall well-being, and stimulating prosocial behavior is the aim of many social-emotional skills interventions. This study assessed if affirming children's autonomy stimulates their psychosocial behavior. We conducted a three-arm microtrial with four repeated measures to assess if a social-emotional skills intervention with an autonomy affirmation component had an additive effect on children's behavior as compared to a "regular" intervention focused exclusively on teaching social-emotional skills and a no-treatment control condition. Our sample consisted of 779 children in Grades 4-6 (Mage = 10.61, SD = 0.93). Findings from latent change modeling demonstrated that the social-emotional skills intervention with an autonomy affirmation component yielded superior effects as compared to the "regular" intervention and the no-treatment control condition on the improvement of internalizing and externalizing problem behavior in the three-month period after the intervention. The intervention with autonomy affirmation did not yield superior effects on prosociality and social skills, self-efficacy, and self-esteem or self-perceived competence. The absence of these effects may be attributed to the dosage of the interventions implemented - the affirmation of children's autonomy may require more than four sessions to sort observable effects. Overall, however, the findings of this study provide an initial suggestion that it may be beneficial to affirm children's autonomy and prosocial intentions when enhancing children's behavior.22 p

Impact of blood storage and sample handling on quality of high dimensional flow cytometric data in multicenter clinical research

Obtaining reliable and reproducible high quality data in multicenter clinical research settings requires design of optimal standard operating procedures. While the need for standardization in sample processing and data analysis is well-recognized, the impact of sample handling in the pre-analytical phase remains underestimated. We evaluated the impact of sample storage time (approximate to transport time) and temperature, type of anticoagulant, and limited blood volume on reproducibility of flow cytometric studies. EDTA and Na-Heparin samples processed with the EuroFlow bulk lysis protocol, stained and stored at 4 degrees C showed fairly stable expression of cell surface markers and distribution of the major leukocyte populations for up to 72 h. Additional sample fixation (1% PFA, Fix & Perm) did not have any beneficial effects. Blood samples stored for < 24 h at room temperature before processing and staining seemed suitable for reliable immunophenotyping, although losses in absolute cell numbers were observed. The major losses were observed in myeloid cells and monocytes, while lymphocytes seemed less affected. Expression of cell surface markers and population distribution were more stable in Na-Heparin blood than in EDTA blood. However, storage of Na-Heparin samples was associated with faster decrease in leukocyte counts over time. Whole blood fixation strategies (Cyto-Chex, TransFix) improved long-term population distribution, but were detrimental for expression of cellular markers. The main conclusions from this study on healthy donor blood samples were successfully confirmed in EDTA clinical (patient) blood samples with different time delays until processing. Finally, we recognized the need for adjustments in bulk lysis in case of insufficient blood volumes. Despite clear overall conclusions, individual markers and cell populations had different preferred conditions. Therefore, specific guidelines for sample handling should always be adjusted to the clinical application and the main target leukocyte population