21,797 research outputs found

    The conduction pathway of potassium channels is water free under physiological conditions.

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    Ion conduction through potassium channels is a fundamental process of life. On the basis of crystallographic data, it was originally proposed that potassium ions and water molecules are transported through the selectivity filter in an alternating arrangement, suggesting a "water-mediated" knock-on mechanism. Later on, this view was challenged by results from molecular dynamics simulations that revealed a "direct" knock-on mechanism where ions are in direct contact. Using solid-state nuclear magnetic resonance techniques tailored to characterize the interaction between water molecules and the ion channel, we show here that the selectivity filter of a potassium channel is free of water under physiological conditions. Our results are fully consistent with the direct knock-on mechanism of ion conduction but contradict the previously proposed water-mediated knock-on mechanism

    Mental rotation meets the motion aftereffect: the role of hV5/MT+ in visual mental imagery

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    A growing number of studies show that visual mental imagery recruits the same brain areas as visual perception. Although the necessity of hV5/MT+ for motion perception has been revealed by means of TMS, its relevance for motion imagery remains unclear. We induced a direction-selective adaptation in hV5/MT+ by means of an MAE while subjects performed a mental rotation task that elicits imagined motion. We concurrently measured behavioral performance and neural activity with fMRI, enabling us to directly assess the effect of a perturbation of hV5/MT+ on other cortical areas involved in the mental rotation task. The activity in hV5/MT+ increased as more mental rotation was required, and the perturbation of hV5/MT+ affected behavioral performance as well as the neural activity in this area. Moreover, several regions in the posterior parietal cortex were also affected by this perturbation. Our results show that hV5/MT+ is required for imagined visual motion and engages in an interaction with parietal cortex during this cognitive process

    Zero kinetic energy-pulsed field ionization and resonance enhanced multiphoton ionization photoelectron spectroscopy: Ionization dynamics of Rydberg states in HBr

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    The results of rotationally resolved resonance enhanced multiphoton ionization photoelectron spectroscopy and zero kinetic energy‐pulsed field ionization studies on HBr via various rotational levels of the F^ 1Δ_2 and f^ 3Δ_2 Rydberg states are reported. These studies lead to an accurate determination of the lowest ionization threshold as 94 098.9±1 cm^(−1). Observed rotational and spin–orbit branching ratios are compared to the results of ab initio calculations. The differences between theory and experiment highlight the dominant role of rotational and spin–orbit interactions for the dynamic properties of the high‐n Rydberg states involved in the pulsed field ionization process

    Universal dynamical decoupling of a single solid-state spin from a spin bath

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    Controlling the interaction of a single quantum system with its environment is a fundamental challenge in quantum science and technology. We dramatically suppress the coupling of a single spin in diamond with the surrounding spin bath by using double-axis dynamical decoupling. The coherence is preserved for arbitrary quantum states, as verified by quantum process tomography. The resulting coherence time enhancement is found to follow a general scaling with the number of decoupling pulses. No limit is observed for the decoupling action up to 136 pulses, for which the coherence time is enhanced more than 25 times compared to spin echo. These results uncover a new regime for experimental quantum science and allow to overcome a major hurdle for implementing quantum information protocols.Comment: submitted 24 May 2010; published online 9 September 201

    Nanopositioning of a diamond nanocrystal containing a single NV defect center

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    Precise control over the position of a single quantum object is important for many experiments in quantum science and nanotechnology. We report on a technique for high-accuracy positioning of individual diamond nanocrystals. The positioning is done with a home-built nanomanipulator under real-time scanning electron imaging, yielding an accuracy of a few nanometers. This technique is applied to pick up, move and position a single NV defect center contained in a diamond nanocrystal. We verify that the unique optical and spin properties of the NV center are conserved by the positioning process.Comment: 3 pages, 3 figures; high-resolution version available at http://www.ns.tudelft.nl/q

    Quasiperiodic Modulated-Spring Model

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    We study the classical vibration problem of a chain with spring constants which are modulated in a quasiperiodic manner, {\it i. e.}, a model in which the elastic energy is jkj(uj1uj)2\sum_j k_j( u_{j-1}-{u_j})^2, where kj=1+Δcos[2πσ(j1/2)+θ]k_j=1+\Delta cos[2\pi\sigma(j-1/2)+\theta] and σ\sigma is an irrational number. For Δ<1\Delta < 1, it is shown analytically that the spectrum is absolutely continuous, {\it i.e.}, all the eigen modes are extended. For Δ=1\Delta=1, numerical scaling analysis shows that the spectrum is purely singular continuous, {\it i.e.}, all the modes are critical.Comment: REV TeX fil

    Direct microwave measurement of Andreev-bound-state dynamics in a proximitized semiconducting nanowire

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    The modern understanding of the Josephson effect in mesosopic devices derives from the physics of Andreev bound states, fermionic modes that are localized in a superconducting weak link. Recently, Josephson junctions constructed using semiconducting nanowires have led to the realization of superconducting qubits with gate-tunable Josephson energies. We have used a microwave circuit QED architecture to detect Andreev bound states in such a gate-tunable junction based on an aluminum-proximitized InAs nanowire. We demonstrate coherent manipulation of these bound states, and track the bound-state fermion parity in real time. Individual parity-switching events due to non-equilibrium quasiparticles are observed with a characteristic timescale Tparity=160±10 μsT_\mathrm{parity} = 160\pm 10~\mathrm{\mu s}. The TparityT_\mathrm{parity} of a topological nanowire junction sets a lower bound on the bandwidth required for control of Majorana bound states
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