Communication organisationnelle : une perspective allagmatique de Valérie Carayol , Paris, L’harmattan, 2004

Derrière le titre énigmatique de ce livre se joue une vision renouvelée de la communication organisationnelle envisagée fondamentalement comme changement (allagma signifiant changement). Le texte de Valérie Carayol repose sur une vision dynamique des organisations qui ne sont pas conçues comme des institutions, comme des monuments dépositaires d’une mémoire et d’une culture ni comme le simple décor d’un jeu d’acteurs engagés dans un jeu de coopération et de conflits. L’organisation est ici co..

Las organizaciones entre relatos y medias

Este artigo considera a comunicação das organizações como a produção de relatos destinados a unificar espacial, temporal e socialmente grupos de trabalho ameaçados de implosão. Esses relatos de legitimação da ação econômica buscam sua inserção na mídia. De alguns anos para cá, e segundo com modalidades que variam de país para país, a mídia generalista tem dedicado um espaço específico para os atores econômicos, enquanto que cresce a importância da imprensa especializada exclusivamente voltada para a ação econômica. Os relatos empresariais, embora substituídos por essa mídia, encontram um espaço privilegiado no sistema midiático criado pelas próprias empresas. Esse sofisticado sistema midiático realiza uma adequação perfeita entre conteúdo e continente, mas sua credibilidade ainda é contestada.Este artículo considera la comunicación de las organizaciones como la producción de relatos destinados a unificar espacial, temporal y socialmente grupos de trabajo amenazados de implosión. Los relatos de legitimación de la acción económica buscan su inserción en la media. Desde alguns años hasta hoy, y segundo modadidades que cambian de país para país, la media generalista tiene dedicado un espacio específico para los actores económicos, mientras crece la importancia de la imprenta especializada exclusivamente direccionada para la acción económica. Los relatos empresariales, aunque substituídos por esa media, encuentran un espacio privilegiado en el sistema mediáticos creado por las mismas empresas. Ese sofisticado sistema mediático realiza una adecuación perfecta entre contenido y continente, pero su credibilidade es todavía puesta en duda

Le développement durable entre temps court et temps long, entre principe de gestion et principe de discussion

 « Vite, vite, de la lenteur », Mozart Le contexte d’émergence du discours du développement durable est marqué par un manque de temps et par un besoin de temps. Le manque de temps est celui de sociétés, d’organisations et d’individus vivant dans l’instant, enfermés dans l’étroitesse du moment, oublieux du passé et incapables d’envisager un avenir. La modernité ou l’hypermodernité sont aujourd’hui définies par un certain nombre d’auteurs un comme rapport particulier au temps, comme  un manque ..

De l’environnement au développement durable, l’institution d’un objet et la configuration d’une question

Cet article propose de montrer comment l'environnement peut être considéré comme un objet important pour les sciences de l'information et de la communication. Il envisage les modalités d'institution de cet objet via la notion de développement durable que nous considérerons ici comme un être de discours. Il analyse l'émergence d'une question et sa transformation dans l'espace public via la notion de développement durable qui rend possible l'inclusion d'acteurs nombreux dans un débat où s'estompe la dimension conflictuelle.This article proposes to show how the environment can be regarded as a significant object for the communication and information sciences. It considers the methods of institution of this object via the concept of sustainable development which is for us a being of speech. This paper analyzes the emergence of a question and its transformation in public space via the concept of sustainable development which makes possible the inclusion of actors many in a debate where desappears conflict dimension

Flight to insight: maximizing the potential of Drosophila models of C9orf72-FTD

Advancements in understanding the pathogenesis of C9orf72-associated frontotemporal dementia (C9orf72-FTD) have highlighted the role of repeat-associated non-ATG (RAN) translation and dipeptide repeat proteins (DPRs), with Drosophila melanogaster models providing valuable insights. While studies have primarily focused on RAN translation and DPR toxicity, emerging areas of investigation in fly models have expanded to neuronal dysfunction, autophagy impairment, and synaptic dysfunction, providing potential directions for new therapeutic targets and mechanisms of neurodegeneration. Despite this progress, there are still significant gaps in Drosophila models of C9orf72-FTD, namely in the areas of metabolism and circadian rhythm. Metabolic dysregulation, particularly lipid metabolism, autophagy, and insulin signaling, has been implicated in disease progression with findings from animal models and human patients with C9orf72 repeat expansions. Moreover, circadian disruptions have been observed in C9of72-FTD, with alterations in rest-activity patterns and cellular circadian machinery, suggesting a potential role in disease pathophysiology. Drosophila models offer unique opportunities to explore these aspects of C9orf72-FTD and identify novel therapeutic targets aimed at mitigating neurodegeneration

Narrativa e comunicação organizacional

Este ensayo visa presentar las contribuciones de la perspectiva narrativa al campo de la comunicación organizacional. Para ello, se analiza la evolución del enfoque narrativo, de los estudios literarios hasta su introducción en el dominio de las ciencias humanas y sociales, destacando, especialmente, el abordaje narratológico de la comunicación organizacional (D’Almeida, 2001). Finalmente, son presentados ejemplos y aplicaciones de dicho enfoque en el contexto organizacional, esperando, con eso, demostrar la pertinencia de los estudios narrativos al campo profesional y científico de la comunicación organizacional.This essay aims to present the contributions of the narrative / narratological approach to the organizational communication. In order to do so, the evolution of the narrative perspective is analyzed, from literary studies to its introduction in the humanities and social sciences, with special emphasis on the narratological approach of organizational communication (D’Almeida, 2001). Finally, examples and applications of such an approach in the organizational context are presented, thereby aiming to demonstrate the relevance of narrative studies to the professional and scientific field of organizational communication.O presente ensaio visa apresentar as contribuições da abordagem narrativa/narratológica à comunicação das organizações. Para tanto, analisa-se a evolução da perspectiva narrativa, dos estudos literários até sua introdução no domínio das ciências humanas e sociais, destacando, especialmente, a abordagem narratológica da comunicação organizacional (D’Almeida, 2001). Finalmente, apresentam-se exemplos e aplicações de tal abordagem no contexto organizacional, almejando, com isso, demonstrar a pertinência dos estudos narrativos ao campo profissional e científico da comunicação organizacional

Diagnosing mucopolysaccharidosis IVA

Mucopolysaccharidosis IVA (MPS IVA; Morquio A syndrome) is an autosomal recessive lysosomal storage disorder resulting from a deficiency of N-acetylgalactosamine-6-sulfate sulfatase (GALNS) activity. Diagnosis can be challenging and requires agreement of clinical, radiographic, and laboratory findings. A group of biochemical genetics laboratory directors and clinicians involved in the diagnosis of MPS IVA, convened by BioMarin Pharmaceutical Inc., met to develop recommendations for diagnosis. The following conclusions were reached. Due to the wide variation and subtleties of radiographic findings, imaging of multiple body regions is recommended. Urinary glycosaminoglycan analysis is particularly problematic for MPS IVA and it is strongly recommended to proceed to enzyme activity testing even if urine appears normal when there is clinical suspicion of MPS IVA. Enzyme activity testing of GALNS is essential in diagnosing MPS IVA. Additional analyses to confirm sample integrity and rule out MPS IVB, multiple sulfatase deficiency, and mucolipidoses types II/III are critical as part of enzyme activity testing. Leukocytes or cultured dermal fibroblasts are strongly recommended for enzyme activity testing to confirm screening results. Molecular testing may also be used to confirm the diagnosis in many patients. However, two known or probable causative mutations may not be identified in all cases of MPS IVA. A diagnostic testing algorithm is presented which attempts to streamline this complex testing process