23 research outputs found
The Effect of Ati (Aptitude Treatment Interaction) Learning Model to Activities and Students Physics Science Generic
This study aims to analyze: (1) the difference between the model of learning activities of students immediately ATI learning model, (2) differences in physical science students\u27 generic capabilities between direct instructional model and learning model ATI. This study was a quasiexperimental study. The population was SMA Negeri 11 students. The sample selection is done at random to randomize the class. The instrument used consisted of: (1) observation sheet learning activity (2) tests the ability of generic science subject matter physics with dynamic power. The test is used to obtain the data is in the form essays. The data in this study were analyzed using a comparative analysis of two independent samples. The results showed that: (1) activity taught students with learning model ATI better than students who are taught using a direct instructional model (2) the ability of generic science physics students taught using learning model ATI better than students who are taught using direct instructional model
Pengembangan Modul Sistem Keamanan Jaringan Berbasis Simulasi Cisco
The aim of this research is to produce and to examine the feasibility of module network security system based simulation Cisco Packet Tracer for vocational learners. The model used is a model development Dick, Carey & Carey with nine steps. The product development is validated by subject matter experts with the level of validity 96%, media expert with the level of validity 92.8%, an instructional design with a level of validity 83%, individual testing at the level of validity 92.3%, small group trial with a level of validity 92% and test field trials with a validity rate of 89% with a very worthy qualification does not need revision.Tujuan penelitian adalah untuk menghasilkan dan menguji kelayakan modul sistem keamanan jaringan berbasis simulasi Cisco Paket Tracer untuk peserta didik SMK. Model pengembangan yang digunakan adalah model Dick, Carey & Carey dengan sembilan langkah. Pengembangan produk ini divalidasi oleh ahli materi dengan tingkat kevalidan 96%, ahli media dengan tingkat kevalidan 92.8%, ahli desain pembelajaran dengan tingkat kevalidan 83%, uji coba perorangan dengan tingkat kevalidan 92.3%, uji coba kelompok kecil dengan tingkat kevalidan 92% dan uji coba lapangan dengan tingkat kevalidan 89% dengan kualifikasi sangat layak tidak perlu revisi
Islam Dan Pekerjaan Sosial
Islamic theology and the fie pillars of Islam have historical and current roles in enhancing Islamic social work practices in Muslim communities. These effects are explored by means of literature review and via comparisons among Muslim populations and other religious followers and with an examination of the theology of Shi\u27i Muslims and Sunni Muslims. Basic concepts of Islam, such as shahada (testimony), prayers, fasting, zakat, and pilgrimage, are recommended for use by Muslim social workers in their practice with Muslim clients
Korelasi Kadar Air, Derajat Kepadatan Relatif dengan Cbr pada Tanah Berbutir
Didalam merencanakan suatu timbunan, baik itu timbunan badan jalan (embankment), maupun reklamasi rawa atau pantai, pasir selalu digunakan sebagai bahan timbunannya. Pemilihan material tersebut karena disamping relatif mudah diperoleh juga harganya lebih murah dibandingkan dengan tanah laterite. Sebelum digunakan sebagai bahan timbunan, terlebih dahulu disarankan membuat job mix (campuran kerja) yang mencakup, karakteristik fisik (Index properties), maupun mekanik (mechanical properties), dari bahan yang akan dipakai sebagai timbunan. Salah satu kriteria yang diminta dalam Job mix, adalah besarnya Kepadatan maximum tanah (γdmax ) dan woptimum, serta besarnya daya dukung tanah (CBR). Penelitian ini dilakukan di laboratorium dengan tujuan untuk mengetahui hubungan antara kadar air (w), derajat kepadatan relative (DR) tanah pasir, dimana hubungan tersebut mempermudah kita dalam menentukan besarnya nilai CBR Laboratorium. Dari hasil analisa statistik menunjukan adanya hubungan yang sangat baik antara kepadatan relatif dengan kadar air terhadap nilai CBR laboratorium, dengan tingkat kepercayaan 95%
Pengaruh Interval Pengendalian Gulma Dan Aplikasi Herbisida Terhadap Pertumbuhan Gulma Dan Tanaman Karet Tbm
Metode pengendalian gulma yang tidak efektif akan menyebabkan dinamika gulma ke jenis yang lebih sulit dikendalikan dan tertundanya matang sadap 2-3 tahun. Penelitian ini untuk mengkaji pertumbuhan gulma dan tanaman karet akibat pengaruh berbagai interval pengendalian dan aplikasi herbisida pada kebun karet TBM. Penelitian dilaksanakan dari Januari 2013 sampai Juni 2014. Rancangan penelitian Split Plot, petak utama adalah perlakuan interval pengendalian gulma dan perlakuan herbisida sebagai anak petak dengan ulangan 3 kali. Hasil penelitian menunjukkan bahwa pertumbuhan gulma daun lebar lebih dominan (SDR 52,76%) dari gulma sempit (SDR 47,24%) di awal penelitian (pra perlakuan). Bobot kering dan penutupan gulma lebih rendah, pada interval pengendalian lebih singkat. Bobot kering gulma antar petak perlakuan berbeda nyata pada Juni dan Desmber 2013. Bobot kering dan penutupan gulma terendah pada perlakuan glifosat + metil metsulfuron yang tertinggi pada perlakuan ditebas dan kontrol. Bobot kering dan penutupan gulma selalu berbeda nyata antara perlakuan glifosat + metil metsulfuron dengan perlakuan ditebas dan kontrol. Perlakuan herbisida campuran parakuat + metil metsulfuron menghasilkan pertumbuhan lilit batang karet lebih baik (17,9 cm) dibanding perlakuan glifosat + metil metsulfuron (16,9 cm). Pertumbuhan lilit batang tanaman karet sangat dipengaruhi bobot kering gulma dengan nilai koefisien diterminasi R2 = 0,82. Dapat disimpulkan bahwa perlakuan herbisida glifosat + metil metsulfuron lebih efektif menekan pertumbuhan gulma dan pertumbuhan lilit batang karet sangat dipengaruhi bobot kering gulma yang membentuk pola hubungan pertumbuhan negatif
Mesin Pencetak Stik Bentuk Akar Kelapa
Besides getas and kemplang, one snack which most people like in Bangka Island isa a snack with the form of a palm tree roots. The craftsmen who manufacture these sticks derived from Pangkalpinang. The results of the survey on the Small Industries (IKM) in the District Gerunggang show that the production process sticks using manual equipment/manpower. To overcome the problems of IKM, hence the researcher designed to facilitate the molding machine in the production process and speed up production so as to produce a better capacity of production by using the manual method. The method used in this research is to design and calculation by using computing devices Solidwork. This stick molding machine uses a mechanism that rotates a threaded shaft, then an emphasis on the dough so that these products can be pushed toward the output. From the experimental results the output of this machine is the root of the stick-shaped palm with a size 100x5 mm, output 500 gram / 5 minutes by the number of ± 80-100 grains stick
Interaction and cellular uptake of surface-modified carbon dot nanoparticles by J774.1 macrophages
Carbon dot (Cdot) nanoparticles are an emerging class of carbon nanomaterials with a promising potential for drug delivery and bio imaging applications. Although the interaction between Cdots and non-immune cell types has been well studied, Cdot interactions with macrophages have not been investigated. Exposure of Cdot nanoparticles to J774.1 cells, a murine macrophage cell line, resulted in minimal toxicity, where notable toxicity was only seen with Cdot concentrations higher than 0.5 mg/ml. Flow cytometric analysis revealed that Cdots prepared from citric acid were internalized at significantly higher levels by macrophages compared with those prepared from bamboo leaves. Interestingly, macrophages preferentially took up phenylboronic acid (PB)-modified nanoparticles. By fluorescence microscopy, strong blue light-specific punctate Cdot fluorescence resembling Cdot structures in the cytosolic space was mostly observed in J774.1 macrophages exposed to PB-modified nanoparticles and not unmodified Cdot nanoparticles. PB binds to sialic acid residues that are overexpressed on diseased cell surfaces. Our findings demonstrate that PB-conjugated Cdots can be taken up by macrophages with low toxicity and high efficiency. These modified Cdots can be used to deliver drugs to suppress or eliminate aberrant immune cells such as macrophages associated with tumors such as tumor-associated macrophages
Impact of primary kidney disease on the effects of empagliflozin in patients with chronic kidney disease: secondary analyses of the EMPA-KIDNEY trial
Background: The EMPA KIDNEY trial showed that empagliflozin reduced the risk of the primary composite outcome of kidney disease progression or cardiovascular death in patients with chronic kidney disease mainly through slowing progression. We aimed to assess how effects of empagliflozin might differ by primary kidney disease across its broad population. Methods: EMPA-KIDNEY, a randomised, controlled, phase 3 trial, was conducted at 241 centres in eight countries (Canada, China, Germany, Italy, Japan, Malaysia, the UK, and the USA). Patients were eligible if their estimated glomerular filtration rate (eGFR) was 20 to less than 45 mL/min per 1·73 m2, or 45 to less than 90 mL/min per 1·73 m2 with a urinary albumin-to-creatinine ratio (uACR) of 200 mg/g or higher at screening. They were randomly assigned (1:1) to 10 mg oral empagliflozin once daily or matching placebo. Effects on kidney disease progression (defined as a sustained ≥40% eGFR decline from randomisation, end-stage kidney disease, a sustained eGFR below 10 mL/min per 1·73 m2, or death from kidney failure) were assessed using prespecified Cox models, and eGFR slope analyses used shared parameter models. Subgroup comparisons were performed by including relevant interaction terms in models. EMPA-KIDNEY is registered with ClinicalTrials.gov, NCT03594110. Findings: Between May 15, 2019, and April 16, 2021, 6609 participants were randomly assigned and followed up for a median of 2·0 years (IQR 1·5–2·4). Prespecified subgroupings by primary kidney disease included 2057 (31·1%) participants with diabetic kidney disease, 1669 (25·3%) with glomerular disease, 1445 (21·9%) with hypertensive or renovascular disease, and 1438 (21·8%) with other or unknown causes. Kidney disease progression occurred in 384 (11·6%) of 3304 patients in the empagliflozin group and 504 (15·2%) of 3305 patients in the placebo group (hazard ratio 0·71 [95% CI 0·62–0·81]), with no evidence that the relative effect size varied significantly by primary kidney disease (pheterogeneity=0·62). The between-group difference in chronic eGFR slopes (ie, from 2 months to final follow-up) was 1·37 mL/min per 1·73 m2 per year (95% CI 1·16–1·59), representing a 50% (42–58) reduction in the rate of chronic eGFR decline. This relative effect of empagliflozin on chronic eGFR slope was similar in analyses by different primary kidney diseases, including in explorations by type of glomerular disease and diabetes (p values for heterogeneity all >0·1). Interpretation: In a broad range of patients with chronic kidney disease at risk of progression, including a wide range of non-diabetic causes of chronic kidney disease, empagliflozin reduced risk of kidney disease progression. Relative effect sizes were broadly similar irrespective of the cause of primary kidney disease, suggesting that SGLT2 inhibitors should be part of a standard of care to minimise risk of kidney failure in chronic kidney disease. Funding: Boehringer Ingelheim, Eli Lilly, and UK Medical Research Council