17 research outputs found
Femtosecond laser thinning for resistivity control of tungsten ditelluride thin-films synthesized from sol-gel deposited tungsten oxide
In this work we present a route for fabricating WTe2 thin-films together with femtosecond laser post processing, enabling to finely control the conductivity. First, we produce amorphous films of WO3 on Si by spin-coating a sol-gel precursor followed by a consolidating annealing and a reduction process in partial H2 atmosphere, leading to porous metallic tungsten cluster layers. To achieve WTe2, the films were exposed to the chalcogen vapours by isothermal closed space vapor transport. The formation of a tungsten ditelluride film composed of piled crystals could be confirmed and a gradient of surface rich Te identified through hard X-ray photoelectron spectroscopy. Finally, it is demonstrated that resistivity can be changed from 0.2 mΩ.m to 1 mΩ.m, while keeping the material characteristics. An anisotropic conductivity can be induced by direct selective thinning with fs laser writing (350 fs pulse duration, 515 nm laser wavelength) of 1D stripes. The obtained results, demonstrate that laser processing is a promising thin-film post-processing technique that can be applied to 2D transition metal dichalcogenide thin filmsPID2020–112770RB-C22, S2018/NMT-4291 TEC2SPACE, CSIC13-4E-179
Plan de negocios para el desarrollo de una tienda virtual de comida saludable por delivery
Comer sano se ha convertido en una tendencia creciente, una alimentaci?n adecuada que cuide el organismo, fortalezca la autoestima y contribuya al ?ptimo rendimiento en la productividad. La idea del negocio es proponer un servicio delivery de comida saludable para la hora del almuerzo, una opci?n con sabor casero, con ingredientes naturales, sin qu?micos y con informaci?n sobre el contenido, las calor?as y peso, unido al respaldo de un nutricionista que orienta y acompa?a a quien desee mantener alg?n r?gimen espec?fico, basado en una dieta nutritiva y balanceada. El cliente tiene la posibilidad de escoger sus ingredientes favoritos, desarrollando un plato personalizado y ser atendido en su centro de trabajo, de lunes a viernes en el horario de almuerzo. La tienda virtual de comida saludable se dirige a una poblaci?n de ejecutivos que trabajan en empresas ubicadas en San Isidro, Miraflores y Surquillo quienes valoran cada vez m?s la alimentaci?n que contribuya con su salud. Como conclusi?n final se tiene que el proyecto es viable, efectuando una inversi?n de S/.40,000. Luego de realizar la evaluaci?n financiera, asumiendo una tasa de descuento de 20% a cinco a?os, resulta un VAN de S/.161,822 y un TIR de 27.72% para un escenario moderado, con lo cual, es factible su ejecuci?n
El Canto del Urutau
Trabalho de Conclusão de Curso - prático apresentado ao Instituto Latino-Americano de Arte, Cultura e História da Universidade Federal da Integração Latino-Americana, como requisito parcial à obtenção do título de Bacharel em Cinema e Audiovisual.Este projeto de conclusão de curso narra o processo de realização do curta-metragem ficcional El Canto del Urutau, que usa a releitura de uma lenda popular (os recémnascidos que, ao não serem batizados, ficam vulneráveis a diversas “forças do mal”) como um dispositivo para narrar as formas de opressão e resistência das instituições e sociedades religiosas fendidas pelo êxodo. Apresentamos em duas partes as questões que acompanharam a realização do filme, desde sua idealização até sua conclusão. A primeira parte contém as bases teóricas que auxiliaram o processo de planejamento da produção dentro do universo ficcional, texto construído durante o TCC II. Na segunda parte, construímos a narrativa que se apresenta como uma espécie de diário da produção do curta-metragem, descrevendo cada etapa da realização do filme dentro das áreas defendidas: direção, fotografia, edição, produção e som
Effects of Platelet-Rich Plasma on Cellular Populations of the Central Nervous System: The Influence of Donor Age
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Effects of Platelet-Rich Plasma on Cellular Populations of the Central Nervous System: The Influence of Donor Age
by Diego Delgado
1, Ane Miren Bilbao
2, Maider Beitia
1, Ane Garate
1, Pello Sánchez
1, Imanol González-Burguera
3,4, Amaia Isasti
4,5, Maider López De Jesús
4,5,6, Jone Zuazo-Ibarra
7, Alejandro Montilla
7 [OrcID] , María Domercq
7 [OrcID] , Estibaliz Capetillo-Zarate
7,8, Gontzal García del Caño
3,4 [OrcID] , Joan Sallés
4,5,6, Carlos Matute
7 and Mikel Sánchez
1,2,*
1
Advanced Biological Therapy Unit, Hospital Vithas Vitoria, 01008 Vitoria-Gasteiz, Spain
2
Arthroscopic Surgery Unit, Hospital Vithas Vitoria, 01008 Vitoria-Gasteiz, Spain
3
Department of Neurosciences, Faculty of Pharmacy, University of the Basque Country (UPV/EHU), 01008 Vitoria-Gasteiz, Spain
4
Bioaraba, Neurofarmacología Celular y Molecular, 01008 Vitoria-Gasteiz, Spain
5
Department of Pharmacology, Faculty of Pharmacy, University of the Basque Country (UPV/EHU), 01008 Vitoria-Gasteiz, Spain
6
Centro de Investigación Biomédica en Red de Salud Mental (CIBERSAM), 28029 Madrid, Spain
7
Achucarro Basque Center for Neuroscience, CIBERNED and Departamento de Neurociencias, Universidad del País Vasco (UPV/EHU), 48940 Leioa, Spain
8
IKERBASQUE, Basque Foundation for Science, 48009 Bilbao, Spain
*
Author to whom correspondence should be addressed.
Academic Editor: Francesca Santilli
Int. J. Mol. Sci. 2021, 22(4), 1725; https://doi.org/10.3390/ijms22041725
Received: 24 November 2020 / Revised: 12 January 2021 / Accepted: 3 February 2021 / Published: 9 February 2021
(This article belongs to the Section Molecular Endocrinology and Metabolism)
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Abstract
Platelet-rich plasma (PRP) is a biologic therapy that promotes healing responses across multiple medical fields, including the central nervous system (CNS). The efficacy of this therapy depends on several factors such as the donor’s health status and age. This work aims to prove the effect of PRP on cellular models of the CNS, considering the differences between PRP from young and elderly donors. Two different PRP pools were prepared from donors 65–85 and 20–25 years old. The cellular and molecular composition of both PRPs were analyzed. Subsequently, the cellular response was evaluated in CNS in vitro models, studying proliferation, neurogenesis, synaptogenesis, and inflammation. While no differences in the cellular composition of PRPs were found, the molecular composition of the Young PRP showed lower levels of inflammatory molecules such as CCL-11, as well as the presence of other factors not found in Aged PRP (GDF-11). Although both PRPs had effects in terms of reducing neural progenitor cell apoptosis, stabilizing neuronal synapses, and decreasing inflammation in the microglia, the effect of the Young PRP was more pronounced. In conclusion, the molecular composition of the PRP, conditioned by the age of the donors, affects the magnitude of the biological response.This work was funded by the Provincial Council of Alava through the AlavaInnova Program, Basque Government through the GAITEK Program, Ministry of Economy, Industry and Competitiveness (CTQ2017-85686-R), Spanish Ministry of Education and Science (PID2019-109724RB-I00), Basque Government (IT1203-19, IT1230-19, and KK-2020/00034) and Centro de Investigación Biomédica en Red en Enfermedades Neurodegenerativas (CIBERNED)
Ceremonial segun las reglas del Missal Romano : ilustrado con doctrinas de los authores mas classicos, antiguos y modernos : methodo de celebrar la missa rezada y cantada ... : ritual preciso a las iglesias cathedrales, colegiales, regulares y parrochiales para su govierno en la celebracion de la missa conventual y solemne ...
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