2,085 research outputs found
Music ranking techniques evaluated
In a music retrieval system, a user presents a piece of music as a query and the system must identify from a corpus of performances other pieces with a similar melody. Several techniques have been proposed for matching such queries to stored music. In previous work, we found that local alignment, a technique derived from bioinformatics, was more effective than the n-gram methods derived from information retrieval; other researchers have reported success with n-grams, but have not compared against local alignment. In this paper we explore a broader range of n-gram techniques, and test them with both manual queries and queries automatically extracted from MIDI files. Our experiments show that n-gram matching techniques can be as effective as local alignment; one highly effective technique is to simply count the number of n-grams in common between the query and the stored piece of music. N-grams are particularly effective for short queries and manual queries, while local alignment is superior for automatic queries
Neutron spectral measurements in the upper atmosphere
An experiment to measure neutrons in the upper atmosphere was performed on a balloon flight from Palestine, Texas, at an altitude of about 32 km. The experimental arrangement is discussed briefly, and results of a preliminary analysis of the data for neutrons in the energy range 3 to 30 MeV are given
Thermal Conductivity, Thermopower, and Figure of Merit of La_{1-x}Sr_xCoO_3
We present a study of the thermal conductivity k and the thermopower S of
single crystals of La_{1-x}Sr_xCoO_3 with 0<= x <= 0.3. For all Sr
concentrations La_{1-x}Sr_xCoO_3 has rather low k values, whereas S strongly
changes as a function of x. We discuss the influence of the temperature- and
the doping-induced spin-state transitions of the Co ions on both, S and k. From
S, k, and the electrical resistivity rho we derive the thermoelectric figure of
merit Z=S^2/(k*rho). For intermediate Sr concentrations we find notably large
values of Z indicating that Co-based materials could be promising candidates
for thermoelectric cooling.Comment: 7 pages, 5 figures included, submitted to Phys. Rev.
Spin-State Transition and Metal-Insulator Transition in LaEuCoO}
We present a study of the structure, the electric resistivity, the magnetic
susceptibility, and the thermal expansion of LaEuCoO. LaCoO
shows a temperature-induced spin-state transition around 100 K and a
metal-insulator transition around 500 K. Partial substitution of La by
the smaller Eu causes chemical pressure and leads to a drastic increase
of the spin gap from about 190 K in LaCoO to about 2000 K in EuCoO, so
that the spin-state transition is shifted to much higher temperatures. A
combined analysis of thermal expansion and susceptibility gives evidence that
the spin-state transition has to be attributed to a population of an
intermediate-spin state with orbital order for and without orbital
order for larger . In contrast to the spin-state transition, the
metal-insulator transition is shifted only moderately to higher temperatures
with increasing Eu content, showing that the metal-insulator transition occurs
independently from the spin-state distribution of the Co ions. Around
the metal-insulator transition the magnetic susceptibility shows a similar
increase for all and approaches a doping-independent value around 1000 K
indicating that well above the metal-insulator transition the same spin state
is approached for all .Comment: 10 pages, 6 figure
The spin state transition in LaCoO; revising a revision
Using soft x-ray absorption spectroscopy and magnetic circular dichroism at
the Co- edge we reveal that the spin state transition in LaCoO
can be well described by a low-spin ground state and a triply-degenerate
high-spin first excited state. From the temperature dependence of the spectral
lineshapes we find that LaCoO at finite temperatures is an inhomogeneous
mixed-spin-state system. Crucial is that the magnetic circular dichroism signal
in the paramagnetic state carries a large orbital momentum. This directly shows
that the currently accepted low-/intermediate-spin picture is at variance.
Parameters derived from these spectroscopies fully explain existing magnetic
susceptibility, electron spin resonance and inelastic neutron data
Accurate and robust genomic prediction of celiac disease using statistical learning.
Practical application of genomic-based risk stratification to clinical diagnosis is appealing yet performance varies widely depending on the disease and genomic risk score (GRS) method. Celiac disease (CD), a common immune-mediated illness, is strongly genetically determined and requires specific HLA haplotypes. HLA testing can exclude diagnosis but has low specificity, providing little information suitable for clinical risk stratification. Using six European cohorts, we provide a proof-of-concept that statistical learning approaches which simultaneously model all SNPs can generate robust and highly accurate predictive models of CD based on genome-wide SNP profiles. The high predictive capacity replicated both in cross-validation within each cohort (AUC of 0.87-0.89) and in independent replication across cohorts (AUC of 0.86-0.9), despite differences in ethnicity. The models explained 30-35% of disease variance and up to ∼43% of heritability. The GRS's utility was assessed in different clinically relevant settings. Comparable to HLA typing, the GRS can be used to identify individuals without CD with ≥99.6% negative predictive value however, unlike HLA typing, fine-scale stratification of individuals into categories of higher-risk for CD can identify those that would benefit from more invasive and costly definitive testing. The GRS is flexible and its performance can be adapted to the clinical situation by adjusting the threshold cut-off. Despite explaining a minority of disease heritability, our findings indicate a genomic risk score provides clinically relevant information to improve upon current diagnostic pathways for CD and support further studies evaluating the clinical utility of this approach in CD and other complex diseases
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