377 research outputs found

    Gender Equality Politics in the Changing European Union: The European Union Anti-Discrimination Directive and Sexual Harassment. CES Working paper, no. 134, 2006

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    The European integration process has provided both challenges and opportunities to domestic women’s movements. One such ambivalent success is the European Union anti-discrimination directive of 2002 that is the outcome of the lobbying efforts of an emerging European transnational advocacy network on gender. The 2002 Directive prohibits sex discrimination, including sexual and gender harassment. It calls on member states to better protect the rights of victims of sexual harassment and to ensure the integrity, dignity, and equality of women and men at work. This paper examines the 2002 Directive and its potential to effect significant changes in EU member states, in particular, to improve victims’ rights in member states laws. It addresses the main question: “Is the EU Directive an opportunity to progress in the direction of protecting victims’ rights?” The argument advanced here is that the 2002 Directive is the outcome of a political compromise among the member states, on which feminist discourses did have some bearing. On the one hand, the 2002 Directive can be interpreted as a success of feminist activism around sexual harassment, in particular, in the very definition, linking the problem to sex discrimination. On the other hand, it has limitations and does not go as far as feminists had hoped; for example, the EU has left it up to member states to deal with the most difficult aspects of the problem, , prevention, implementation, and enforcement of the laws

    Revisit Sparse Polynomial Interpolation based on Randomized Kronecker Substitution

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    In this paper, a new reduction based interpolation algorithm for black-box multivariate polynomials over finite fields is given. The method is based on two main ingredients. A new Monte Carlo method is given to reduce black-box multivariate polynomial interpolation to black-box univariate polynomial interpolation over any ring. The reduction algorithm leads to multivariate interpolation algorithms with better or the same complexities most cases when combining with various univariate interpolation algorithms. We also propose a modified univariate Ben-or and Tiwarri algorithm over the finite field, which has better total complexity than the Lagrange interpolation algorithm. Combining our reduction method and the modified univariate Ben-or and Tiwarri algorithm, we give a Monte Carlo multivariate interpolation algorithm, which has better total complexity in most cases for sparse interpolation of black-box polynomial over finite fields

    Gender equality in German universities: vernacularising the battle for the best brains

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    We examine how global pressures for competitiveness and gender equality have merged into a discourse of ‘inclusive excellence’ in the twenty-first century and shaped three recent German higher education programmes. After placing these programmes in the larger discourse about gender inequalities, we focus on how they adapt current global concerns about both being ‘the best’ and increasing ‘gender equality’ in locally specific ways, a process called vernacularisation. German equality advocates used ‘meeting international standards’ as leverage, drew on self-governance norms among universities, used formal gender plans as mechanisms to direct change, and set up competition to legitimate intervention. This specific incremental policy path for increasing women's status in German universities also mobilised the national funding agency and local gender equality officers as key actors, and placed particular emphasis on family friendliness as the expression of organisational commitment to gender equality

    Systemic TLR2 agonist exposure regulates hematopoietic stem cells via cell-autonomous and cell-non-autonomous mechanisms

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    Toll-like receptor 2 (TLR2) is a member of the TLR family of receptors that play a central role in innate immunity. In addition to regulating effector immune cells, where it recognizes a wide variety of pathogen-associated and nonpathogen-associated endogenous ligands, TLR2 is expressed in hematopoietic stem cells (HSCs). Its role in HSCs, however, is not well understood. Furthermore, augmented TLR2 signaling is associated with myelodysplastic syndrome, an HSC disorder characterized by ineffective hematopoiesis and a high risk of transformation to leukemia, suggesting that aberrant signaling through this receptor may have clinically significant effects on HSCs. Herein, we show that systemic exposure of mice to a TLR2 agonist leads to an expansion of bone marrow and spleen phenotypic HSCs and progenitors, but a loss of HSC self-renewal capacity. Treatment of chimeric animals shows that these effects are largely cell non-autonomous, with a minor contribution from cell-autonomous TLR2 signaling, and are in part mediated by granulocyte colony-stimulating factor and tumor necrosis factor-α. Together, these data suggest that TLR2 ligand exposure influences HSC cycling and function via unique mechanisms from TLR4, and support an important role for TLR2 in the regulation of HSCs

    Controlling Regioselectivity in Palladium-Catalyzed C-H Activation/Aryl-Aryl Coupling of 4-Phenylamino[2.2]paracyclophane

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    Selective activation/functionalization of C-H bonds has emerged as an atom- and step-economical process at the forefront of modern synthetic chemistry. This work reports palladium-catalyzed exclusivelypara-selective C-H activation/aryl-aryl bond formation with a preference overN-arylation under the Buchwald-Hartwig amination reaction of 4-phenylamino[2.2]paracyclophane. This innovative synthetic strategy allows a facile preparation of [2.2]paracyclophane derivatives featuring disparatepara-substitutions at C-4 and C-7 positions in a highly selective manner, gives access to a series of potential candidates for [2.2]paracyclophane-derived new planar chiral ligands. The unprecedented behavior in reactivity and preferential selectivity of C-C coupling over C-N bond formation via C-H activation is unique to the [2.2]paracyclophane scaffold compared to the non-cyclophane analogue under the same reaction conditions. Selective C-H activation/aryl-aryl bond formation and sequential C-N coupling product formation is evidenced unambiguously by X-ray crystallography.Peer reviewe

    The inverse moment problem for convex polytopes

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    The goal of this paper is to present a general and novel approach for the reconstruction of any convex d-dimensional polytope P, from knowledge of its moments. In particular, we show that the vertices of an N-vertex polytope in R^d can be reconstructed from the knowledge of O(DN) axial moments (w.r.t. to an unknown polynomial measure od degree D) in d+1 distinct generic directions. Our approach is based on the collection of moment formulas due to Brion, Lawrence, Khovanskii-Pukhikov, and Barvinok that arise in the discrete geometry of polytopes, and what variously known as Prony's method, or Vandermonde factorization of finite rank Hankel matrices.Comment: LaTeX2e, 24 pages including 1 appendi
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