Exploring cybersecurity-related emotions and finding that they are challenging to measure

This paper reports on a three-part investigation into people’s perceptions of cybersecurity, based on their lived experiences. We sought thereby to reveal issues located within the Johari grid’s “Blind Spot” quadrant. We utilized research methodologies from both the Arts and Science in order firstly to identify blind spot issues, and secondly to explore their dimensions. Our investigation confirmed a number of aspects that we were indeed aware of, when it came to people’s lived cybersecurity experiences. We also identified one particular blind spot issue: widespread, but not universal, negativity towards cybersecurity. We then carried out an investigation using a recognized methodology from psychology, as a first attempt to assess the nature of this negativity and to get a sense of its roots. What our initial experiment revealed was that scoping cybersecurity-related emotions is nontrivial and will require the formulation of new measurement tools. We conclude by reporting on the challenges, to inform researchers who plan to extend the research reported in this paper

A method to reconstruct flood scenarios using field interviews and hydrodynamic modelling: application to the 2017 Suleja and Tafa, Nigeria flood

Abstract The scarcity of model input and calibration data has limited efforts in reconstructing scenarios of past floods in many regions globally. Recently, the number of studies that use distributed post-flood observation data collected throughout flood-affected communities (e.g. face-to-face interviews) are increasing. However, a systematic method that applies such data for hydrodynamic modelling of past floods in locations without hydrological is lacking. In this study, we developed a method for reconstructing plausible scenarios of past flood events in data-scarce regions by applying flood observation data collected through field interviews to a hydrodynamic model (CAESAR-Lisflood). We tested the method using 300 spatially distributed flood depths and duration data collected using questionnaires on five river reaches after the 2017 flood event in Suleja and Tafa region, Nigeria. A stepwise process that aims to minimize the error between modelled and observed flood depth and duration at the locations of interviewed households was implemented. Results from the reconstructed flood depth scenario produced an error of ± 0.61 m for all observed and modelled locations and lie in the range of error produced by studies using comparable hydrodynamic models. The study demonstrates the potential of utilizing interview data for hydrodynamic modelling applications in data-scarce regions to support regional flood risk assessment. Furthermore, the method can provide flow depths and durations at houses without observations, which is useful input data for physical vulnerability assessment to complement disaster risk reduction efforts

Human isotype‐dependent inhibitory antibody responses against Mycobacterium tuberculosis

Accumulating evidence from experimental animal models suggests that antibodies play a protective role against tuberculosis (TB). However, little is known about the antibodies generated upon Mycobacterium tuberculosis (MTB) exposure in humans. Here, we performed a molecular and functional characterization of the human B‐cell response to MTB by generating recombinant monoclonal antibodies from single isolated B cells of untreated adult patients with acute pulmonary TB and from MTB‐exposed healthcare workers. The data suggest that the acute plasmablast response to MTB originates from reactivated memory B cells and indicates a mucosal origin. Through functional analyses, we identified MTB inhibitory antibodies against mycobacterial antigens including virulence factors that play important roles in host cell infection. The inhibitory activity of anti‐MTB antibodies was directly linked to their isotype. Monoclonal as well as purified serum IgA antibodies showed MTB blocking activity independently of Fc alpha receptor expression, whereas IgG antibodies promoted the host cell infection. Together, the data provide molecular insights into the human antibody response to MTB and may thereby facilitate the design of protective vaccination strategies

How to handle the Sympathetic Nervous System

Zimmermann E, Vobejda C, Schürmann C, Wienecke E. How to handle the Sympathetic Nervous System. Presented at the XXV FIMS World Congress, Athen