The Zieschang-McCool method for generating algebraic mapping-class groups

Let g and p be non-negative integers. Let A(g,p) denote the group consisting of all those automorphisms of the free group on {t_1,...,t_p, x_1,...,x_g, y_1,...y_g} which fix the element t_1t_2...t_p[x_1,y_1]...[x_g,y_g] and permute the set of conjugacy classes {[t_1],....,[t_p]}. Labru\`ere and Paris, building on work of Artin, Magnus, Dehn, Nielsen, Lickorish, Zieschang, Birman, Humphries, and others, showed that A(g,p) is generated by a set that is called the ADLH set. We use methods of Zieschang and McCool to give a self-contained, algebraic proof of this result. Labru\`ere and Paris also gave defining relations for the ADLH set in A(g,p); we do not know an algebraic proof of this for g > 1. Consider an orientable surface S(g,p) of genus g with p punctures, such that (g,p) is not (0,0) or (0,1). The algebraic mapping-class group of S(g,p), denoted M(g,p), is defined as the group of all those outer automorphisms of the one-relator group with generating set {t_1,...,t_p, x_1,...,x_g, y_1,...y_g} and relator t_1t_2...t_p[x_1,y_1]...[x_g,y_g] which permute the set of conjugacy classes {[t_1],....,[t_p]}. It now follows from a result of Nielsen that M(g,p) is generated by the image of the ADLH set together with a reflection. This gives a new way of seeing that M(g,p) equals the (topological) mapping-class group of S(g,p), along lines suggested by Magnus, Karrass, and Solitar in 1966.Comment: 21 pages, 0 figure

Thurston equivalence of topological polynomials

We answer Hubbard's question on determining the Thurston equivalence class of ``twisted rabbits'', i.e. images of the ``rabbit'' polynomial under n-th powers of the Dehn twists about its ears. The answer is expressed in terms of the 4-adic expansion of n. We also answer the equivalent question for the other two families of degree-2 topological polynomials with three post-critical points. In the process, we rephrase the questions in group-theoretical language, in terms of wreath recursions.Comment: 40 pages, lots of figure

Topology of energy surfaces and existence of transversal Poincar\'e sections

Two questions on the topology of compact energy surfaces of natural two degrees of freedom Hamiltonian systems in a magnetic field are discussed. We show that the topology of this 3-manifold (if it is not a unit tangent bundle) is uniquely determined by the Euler characteristic of the accessible region in configuration space. In this class of 3-manifolds for most cases there does not exist a transverse and complete Poincar\'e section. We show that there are topological obstacles for its existence such that only in the cases of $S^1\times S^2$ and $T^3$ such a Poincar\'e section can exist.Comment: 10 pages, LaTe

Virtually abelian K\"ahler and projective groups

We characterise the virtually abelian groups which are fundamental groups of compact K\"ahler manifolds and of smooth projective varieties. We show that a virtually abelian group is K\"ahler if and only if it is projective. In particular, this allows to describe the K\"ahler condition for such groups in terms of integral symplectic representations

Local chromatic number of quadrangulations of surfaces

The local chromatic number of a graph G, as introduced in [4], is the minimum integer k such that G admits a proper coloring (with an arbitrary number of colors) in which the neighborhood of each vertex uses less than k colors. In [17] a connection of the local chromatic number to topological properties of (a box complex of) the graph was established and in [18] it was shown that a topological condition implying the usual chromatic number being at least four has the stronger consequence that the local chromatic number is also at least four. As a consequence one obtains a generalization of the following theorem of Youngs [19]: If a quadrangulation of the projective plane is not bipartite it has chromatic number four. The generalization states that in this case the local chromatic number is also four. Both papers [1] and [13] generalize Youngs’ result to arbitrary non-orientable surfaces replacing the condition of the graph being not bipartite by a more technical condition of an odd quadrangulation. This paper investigates when these general results are true for the local chromatic number instead of the chromatic number. Surprisingly, we find out that (unlike in the case of the chromatic number) this depends on the genus of the surface. For the non-orientable surfaces of genus at most four, the local chromatic number of any odd quadrangulation is at least four, but this is not true for non-orientable surfaces of genus 5 or higher. We also prove that face subdivisions of odd quadrangulations and Fisk triangulations of arbitrary surfaces exhibit the same behavior for the local chromatic number as they do for the usual chromatic number

Remarks on singular Cayley graphs and vanishing elements of simple groups

Let Γ be a finite graph and let A(Γ) be its adjacency matrix. Then Γ is singular if A(Γ) is singular. The singularity of graphs is of certain interest in graph theory and algebraic combinatorics. Here we investigate this problem for Cayley graphs Cay(G,H) when G is a finite group and when the connecting set H is a union of conjugacy classes of G. In this situation, the singularity problem reduces to finding an irreducible character χ of G for which ∑h∈Hχ(h)=0. At this stage, we focus on the case when H is a single conjugacy class hG of G; in this case, the above equality is equivalent to χ(h)=0 . Much is known in this situation, with essential information coming from the block theory of representations of finite groups. An element h∈G is called vanishing if χ(h)=0 for some irreducible character χ of G. We study vanishing elements mainly in finite simple groups and in alternating groups in particular. We suggest some approaches for constructing singular Cayley graphs

The Role of Multidimensional Prognostic Index to Identify Hospitalized Older Adults with COVID-19 Who Can Benefit from Remdesivir Treatment: An Observational, Prospective, Multicenter Study

Background: Data regarding the importance of multidimensional frailty to guide clinical decision making for remdesivir use in older patients with coronavirus disease 2019 (COVID-19) are largely unexplored. Objective: The aim of this research was to evaluate if the Multidimensional Prognostic Index (MPI), a multidimensional frailty tool based on the Comprehensive Geriatric Assessment (CGA), may help physicians in identifying older hospitalized patients affected by COVID-19 who might benefit from the use of remdesivir. Methods: This was a multicenter, prospective study of older adults hospitalized for COVID-19 in 10 European hospitals, followed-up for 90 days after hospital discharge. A standardized CGA was performed at hospital admission and the MPI was calculated, with a final score ranging between 0 (lowest mortality risk) and 1 (highest mortality risk). We assessed survival with Cox regression, and the impact of remdesivir on mortality (overall and in hospital) with propensity score analysis, stratified by MPI = 0.50. Results: Among 496 older adults hospitalized for COVID-19 (mean age 80 years, female 59.9%), 140 (28.2% of patients) were treated with remdesivir. During the 90 days of follow-up, 175 deaths were reported, 115 in hospital. Remdesivir treatment significantly reduced the risk of overall mortality (hazard ratio [HR] 0.54, 95% confidence interval CI 0.35–0.83 in the propensity score analysis) in the sample as whole. Stratifying the population, based on MPI score, the effect was observed only in less frail participants (HR 0.47, 95% CI 0.22–0.96 in propensity score analysis), but not in frailer subjects. In-hospital mortality was not influenced by remdesivir use. Conclusions: MPI could help to identify less frail older adults hospitalized for COVID-19 who could benefit more from remdesivir treatment in terms of long-term survival