Applications of serum amino acid levels in identification of cancer

Chemometric method of uncorrelated linear discriminant analysis (ULDA) was applied to the data of amino acid levels in serum of lung cancer patients and healthy people, eventually successfully classifies the samples of cancer patients and healthy people. Simultaneously, several potential amino acid biomarkers were possibly chosen. So the method of amino acid levels combined with ULDA algorithm could be applied to the identification of cancer and exploration of tumor biomarker, which has certain practical value and application prospects

A Miniaturized In Situ Tensile Platform under Microscope

Aiming at the mechanical testing of three-dimensional specimens with feature size of centimeter level, a miniaturized tensile platform, which presents compatibility with scanning electron microscope (SEM) and metallographic microscope, was designed and built. The platform could accurately evaluate the parameters such as elastic modulus, elongation and yield limit, etc. The calibration experiments of load sensor and displacement sensor showed the two kinds of sensors had high linearity. Testing of transmission error and modal parameters showed that the platform presented good following behaviors and separation of resonance region. Comparison tests based on stress-strain curve were carried out between the self-made platform and the commercial tensile instrument (Instron) to verify the feasibility of the platform. Furthermore, the in situ tensile experiment under metallographic microscope was carried out on a kind of manganese steel