3,210 research outputs found
Innovation with Chinese characteristics: theory and practice
Purpose This is a special issue of Chinese Management Studies and this study aims to engage with debates on innovation in China and to provide new insights for innovation research in the context of China, seeking to develop a greater understanding of the concept of âinnovation with Chinese characteristicsâ.
Design/methodology/approach This study reviews the Chinese innovation management literature in general and the selected papers in this special issue in particular and proposes two new directions for future research.
Findings The nine papers that constitute this special issue present research on important aspects of innovation in China, ranging from the effectiveness of government subsidisation for innovation, the impact of fiscal decentralisation on innovation, the role of management behaviour in promoting (or discouraging) innovation and the effects of differing business models on innovation. These papers shed valuable new light on the theory and practice of innovation in China. The papers are discussed in the context of four primary arguments about innovation management in China identified from the broader literature in the field. These relate to the pattern of Chinaâs innovation performance over time, the reasons for its effectiveness, the role of alliances and influences of indigenous factors. It is also shown that management of the internationalisation of innovation and of efficient internal innovation are two important directions for future research on Chinese innovation in an era of de-globalisation.
Originality/value The studies presented here provide valuable contributions to theory building in innovation research, as well as some important ideas for directions of future research on innovation in China in the new era of de-globalisation
Comparative proteomic profiling reveals molecular characteristics associated with oogenesis and oocyte maturation during ovarian development of Bactrocera dorsalis (Hendel)
Time-dependent expression of proteins in ovary is important to understand oogenesis in insects. Here, we profiled the proteomes of developing ovaries from Bactrocera dorsalis (Hendel) to obtain information about ovarian development with particular emphasis on differentially expressed proteins (DEPs) involved in oogenesis. A total of 4838 proteins were identified with an average peptide number of 8.15 and sequence coverage of 20.79%. Quantitative proteomic analysis showed that a total of 612 and 196 proteins were differentially expressed in developing and mature ovaries, respectively. Furthermore, 153, 196 and 59 potential target proteins were highly expressed in early, vitellogenic and mature ovaries and most tested DEPs had the similar trends consistent with the respective transcriptional profiles. These proteins were abundantly expressed in pre-vitellogenic and vitellogenic stages, including tropomyosin, vitellogenin, eukaryotic translation initiation factor, heat shock protein, importin protein, vitelline membrane protein, and chorion protein. Several hormone and signal pathway related proteins were also identified during ovarian development including piRNA, notch, insulin, juvenile, and ecdysone hormone signal pathways. This is the first report of a global ovary proteome of a tephritid fruit fly, and may contribute to understanding the complicate processes of ovarian development and exploring the potentially novel pest control targets
Analysis and Application of Extension Correlation and Correspondence under Uncertainty
This paper studies the meaning, nature of extension correspondence and analyzes its superiority in data prediction in extension group decision-making by analyzing the distance and bit value of the correlation function. It puts forward the model and steps of data interval analysis of extension group decision-making based on extension correspondence. Not only does it take the advantages of dynamic classification in extension group decision-making, but also realizes data analysis and interval estimation under uncertainty and helps the promotion of the accuracy and the reliability of multi-factor analysis and multi-project evaluation in extension group decision-making under data uncertainty. Keywords: extension set; extension group decision-making; correlation function; correspondence analysis; uncertaint
Wave attenuation and focusing performance of parallel twin parabolic arc floating breakwaters
The hybrid system consisting of floating breakwater and point absorber wave energy converters provides a promising solution for shoreline protection and wave power generation. In the hybrid system, the breakwater plays an important role in protecting the sheltered area on the lee side and focusing high waves for better energy harvesting on the weather side. To improve the wave attenuation and focusing performance, a twin-breakwater consisting of a pair of parallel parabolic pontoons is proposed. Based on the potential flow theory of linear waves, the influences of gap width and connection method applied between the two pontoons are studied in the frequency domain, with an emphasis on the so-called critical mode around which both wave attenuation and focusing could be improved. Results show that the rigidly connected twin-breakwater is superior to the unconnected twin-breakwater with the same configuration in both wave attenuation and focusing. A second critical mode with lower frequency is also found under particular gap width, providing a potential for the defense of long waves. An optimal attenuation could be obtained by applying a proper gap width
Leaching and microstructural properties of lead contaminated kaolin stabilized by GGBS-MgO in semi-dynamic leaching tests
Ground granulated blast furnace slag (GGBS) is widely used to stabilize soils due to its environmental and economic merits. The strength and durability of reactive MgO activated GGBS (GGBS-MgO) stabilized lead (Pb)-contaminated soils have been explored by previous studies. However, the effects of simulated acid rain (SAR) on the leachability and micro-properties of GGBS-MgO stabilized Pb-contaminated soils are hardly investigated. This research studies the leachability and microstructural properties of GGBS-MgO stabilized Pb-contaminated kaolin clay exposed to SAR with initial pH values of 2.0, 4.0 and 7.0. A series of tests are performed including the semi-dynamic leaching tests using SAR as the extraction liquid, acid neutralization capacity (ANC), mercury intrusion porosimetry (MIP), and X-ray diffraction (XRD) tests. The results demonstrate that as the SAR pH decreases from 7.0 to 4.0, the Pb cumulative fraction leached (CFL) and observed diffusion coefficient (Dobs) increases significantly whereas the leachate pH decreases. Meanwhile, increasing the GGBS-MgO content from 12% to 18% results in the decrease of CFL and Dobs. Further decreasing the SAR pH to 2.0 results in the dissolution-controlled leaching mechanism regardless of the binder dosage. The differences in the leaching properties under different pH conditions are interpreted based on the cemented soil acid buffering capacity, hydration products and pore size distributions obtained from the ANC, MIP, and XRD tests, respectively
Hidden Tree Structure is a Key to the Emergence of Scaling in the World Wide Web
Preferential attachment is the most popular explanation for the emergence of
scaling behavior in the World Wide Web, but this explanation has been
challenged by the global information hypothesis, the existence of linear
preference and the emergence of new big internet companies in the real world.
We notice that most websites have an obvious feature that their pages are
organized as a tree (namely hidden tree) and hence propose a new model that
introduces a hidden tree structure into the Erd\H{o}s-R\'e}yi model by adding a
new rule: when one node connects to another, it should also connect to all
nodes in the path between these two nodes in the hidden tree. The experimental
results show that the degree distribution of the generated graphs would obey
power law distributions and have variable high clustering coefficients and
variable small average lengths of shortest paths. The proposed model provides
an alternative explanation to the emergence of scaling in the World Wide Web
without the above-mentioned difficulties, and also explains the "preferential
attachment" phenomenon.Comment: 4 Pages, 7 Figure
DNMT3a in the hippocampal CA1 is crucial in the acquisition of morphine selfâadministration in rats
Drugâreinforced excessive operant responding is one fundamental feature of long-lasting addictionâlike behaviors and relapse in animals. However, the transcriptional regulatory mechanisms responsible for the persistent drugâspecific (not natural rewards) operant behavior are not entirely clear. In this study, we demonstrate a key role for one of the de novo DNA methyltransferase, DNMT3a, in the acquisition of morphine selfâadministration (SA) in rats. The expression of DNMT3a in the hippocampal CA1 region but not in the nucleus accumbens shell was significantly upâregulated after 1â and 7âday morphine SA (0.3 mg/kg/infusion) but not after the yoked morphine injection. On the other hand, saccharin SA did not affect the expression of DNMT3a or DNMT3b. DNMT inhibitor 5âazaâ2âdeoxycytidine (5âaza) microinjected into the hippocampal CA1 significantly attenuated the acquisition of morphine SA. Knockdown of DNMT3a also impaired the ability to acquire the morphine SA. Overall, these findings suggest that DNMT3a in the hippocampus plays an important role in the acquisition of morphine SA and may be a valid target to prevent the development of morphine addiction.
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