Correction of the definition of mass-flow parameter in dynamic inflow modelling

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PRDM14 is expressed in germ cell tumors with constitutive overexpression altering human germline differentiation and proliferation.

Germ cell tumors (GCTs) are a heterogeneous group of tumors occurring in gonadal and extragonadal locations. GCTs are hypothesized to arise from primordial germ cells (PGCs), which fail to differentiate. One recently identified susceptibility loci for human GCT is PR (PRDI-BF1 and RIZ) domain proteins 14 (PRDM14). PRDM14 is expressed in early primate PGCs and is repressed as PGCs differentiate. To examine PRDM14 in human GCTs we profiled human GCT cell lines and patient samples and discovered that PRDM14 is expressed in embryonal carcinoma cell lines, embryonal carcinomas, seminomas, intracranial germinomas and yolk sac tumors, but is not expressed in teratomas. To model constitutive overexpression in human PGCs, we generated PGC-like cells (PGCLCs) from human pluripotent stem cells (PSCs) and discovered that elevated expression of PRDM14 does not block early PGC formation. Instead, we show that elevated PRDM14 in PGCLCs causes proliferation and differentiation defects in the germline

Dynamics of spin transport in voltage-biased Josephson junctions

We investigate spin transport in voltage-biased spin-active Josephson junctions. The interplay of spin filtering, spin mixing, and multiple Andreev reflection leads to nonlinear voltage dependence of the dc and ac spin current. We compute the voltage characteristics of the spin current (I_S) for superconductor-ferromagnet-superconductor (SFS) Josephson junctions. The sub-harmonic gap structure of I_S(V) is shown to be sensitive to the degree of spin mixing generated by the ferromagnetic interface, and exhibits a pronounced even-odd effect associated with spin transport during multiple Andreev reflection processes. For strong spin mixing both the magnitude and the direction of the dc spin current can be sensitively controlled by the bias voltage.Comment: 4 pages, 3 figure

Signatures of Emerging Subsurface Structures in Acoustic Power Maps

We show that under certain conditions, subsurface structures in the solar interior can alter the average acoustic power observed at the photosphere above them. By using numerical simulations of wave propagation, we show that this effect is large enough for it to be potentially used for detecting emerging active regions before they appear on the surface. In our simulations, simplified subsurface structures are modeled as regions with enhanced or reduced acoustic wave speed. We investigate the dependence of the acoustic power above a subsurface region on the sign, depth, and strength of the wave speed perturbation. Observations from the Solar and Heliospheric Observatory/Michelson Doppler Imager (SOHO/MDI) prior and during the emergence of NOAA active region 10488 are used to test the use of acoustic power as a potential precursor of magnetic flux emergence.Comment: 7 pages, 5 figures, accepted for publication in Solar Physics on 21 March 201

Microscopic study of induced fission dynamics of 226^{226}Th with covariant energy density functionals

Static and dynamic aspects of the fission process of $^{226}$Th are analyzed in a self-consistent framework based on relativistic energy density functionals. Constrained relativistic mean-field (RMF) calculations in the collective space of axially symmetric quadrupole and octupole deformations, based on the energy density functional PC-PK1 and a $\delta$-force pairing, are performed to determine the potential energy surface of the fissioning nucleus, the scission line, the single-nucleon wave functions, energies and occupation probabilities, as functions of deformation parameters. Induced fission dynamics is described using the time-dependent generator coordinate method in the Gaussian overlap approximation. A collective Schr\"odinger equation, determined entirely by the microscopic single-nucleon degrees of freedom, propagates adiabatically in time the initial wave packet built by boosting the ground-state solution of the collective Hamiltonian for $^{226}$Th. The position of the scission line and the microscopic input for the collective Hamiltonian are analyzed as functions of the strength of the pairing interaction. The effect of static pairing correlations on the pre-neutron emission charge yields and total kinetic energy of fission fragments is examined in comparison with available data, and the distribution of fission fragments is analyzed for different values of the initial excitation energy.Comment: 25 pages, 14 figures, accepted for publication in Phys. Rev.

Tracers of chromospheric structure. I. CaII H&\&K emission distribution of 13000 F, G and K stars in SDSS DR7 spectroscopic sample

We present chromospheric activity index $S\rm_{HK}$ measurements for over 13,000 F, G and K disk stars with high signal-to-noise ratio ($>$ 60) spectra in the Sloan Digital Sky Survey (SDSS) Data Release 7 (DR7) spectroscopic sample. A parameter $\delta$S is defined as the difference between $S\rm_{HK}$ and a `zero' emission line fitted by several of the most inactive stars. The $S\rm_{HK}$ indices of subgiant stars tend to be much lower than dwarfs, which provide a way to distinguish dwarfs and giants with relatively low resolution spectra. Cooler stars are generally more active and display a larger scatter than hotter stars. Stars associated with the thick disk are in general less active than those of the thin disk. The fraction of K dwarfs that are active drops with vertical distance from the Galactic plane. Metallicity affects $S\rm_{HK}$ measurements differently among F, G and K dwarfs in this sample. Using the open clusters NGC 2420, M67 and NGC6791 as calibrations, ages of most field stars in this SDSS sample range from 3-8 Gyr.Comment: 9 pages, 11 figures, AJ, 2013, 145, 14

Heat conduction in graphene flakes with inhomogeneous mass interface

Using nonequilibrium molecular dynamics simulations, we study the heat conduction in graphene flakes composed by two regions. One region is mass-loaded and the other one is intact. It is found that the mass interface between the two regions greatly decreases the thermal conductivity, but it would not bring thermal rectification effect. The dependence of thermal conductivity upon the heat flux and the mass difference ratio are studied to confirm the generality of the result. The interfacial scattering of solitons is studied to explain the absence of rectification effect.Comment: 5 pages, 4 figure