30 research outputs found

    BEV-IO: Enhancing Bird's-Eye-View 3D Detection with Instance Occupancy

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    A popular approach for constructing bird's-eye-view (BEV) representation in 3D detection is to lift 2D image features onto the viewing frustum space based on explicitly predicted depth distribution. However, depth distribution can only characterize the 3D geometry of visible object surfaces but fails to capture their internal space and overall geometric structure, leading to sparse and unsatisfactory 3D representations. To mitigate this issue, we present BEV-IO, a new 3D detection paradigm to enhance BEV representation with instance occupancy information. At the core of our method is the newly-designed instance occupancy prediction (IOP) module, which aims to infer point-level occupancy status for each instance in the frustum space. To ensure training efficiency while maintaining representational flexibility, it is trained using the combination of both explicit and implicit supervision. With the predicted occupancy, we further design a geometry-aware feature propagation mechanism (GFP), which performs self-attention based on occupancy distribution along each ray in frustum and is able to enforce instance-level feature consistency. By integrating the IOP module with GFP mechanism, our BEV-IO detector is able to render highly informative 3D scene structures with more comprehensive BEV representations. Experimental results demonstrate that BEV-IO can outperform state-of-the-art methods while only adding a negligible increase in parameters (0.2%) and computational overhead (0.24%in GFLOPs).Comment: v

    From GPT-4 to Gemini and Beyond: Assessing the Landscape of MLLMs on Generalizability, Trustworthiness and Causality through Four Modalities

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    Multi-modal Large Language Models (MLLMs) have shown impressive abilities in generating reasonable responses with respect to multi-modal contents. However, there is still a wide gap between the performance of recent MLLM-based applications and the expectation of the broad public, even though the most powerful OpenAI's GPT-4 and Google's Gemini have been deployed. This paper strives to enhance understanding of the gap through the lens of a qualitative study on the generalizability, trustworthiness, and causal reasoning capabilities of recent proprietary and open-source MLLMs across four modalities: ie, text, code, image, and video, ultimately aiming to improve the transparency of MLLMs. We believe these properties are several representative factors that define the reliability of MLLMs, in supporting various downstream applications. To be specific, we evaluate the closed-source GPT-4 and Gemini and 6 open-source LLMs and MLLMs. Overall we evaluate 230 manually designed cases, where the qualitative results are then summarized into 12 scores (ie, 4 modalities times 3 properties). In total, we uncover 14 empirical findings that are useful to understand the capabilities and limitations of both proprietary and open-source MLLMs, towards more reliable downstream multi-modal applications

    Systematic analysis of the necroptosis index in pan-cancer and classification in discriminating the prognosis and immunotherapy responses of 1716 glioma patients

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    Necroptosis is a programmed form of necrotic cell death that serves as a host gatekeeper for defense against invasion by certain pathogens. Previous studies have uncovered the essential role of necroptosis in tumor progression and implied the potential for novel therapies targeting necroptosis. However, no comprehensive analysis of multi-omics data has been conducted to better understand the relationship between necroptosis and tumor. We developed the necroptosis index (NI) to uncover the effect of necroptosis in most cancers. NI not only correlated with clinical characteristics of multiple tumors, but also could influence drug sensitivity in glioma. Based on necroptosis-related differentially expressed genes, the consensus clustering was used to classify glioma patients into two NI subgroups. Then, we revealed NI subgroup I were more sensitive to immunotherapy, particularly anti-PD1 therapy. This new NI-based classification may have prospective predictive factors for prognosis and guide physicians in prioritizing immunotherapy for potential responders

    Investigation of nonlinear wave-induced seabed response around mono-pile foundation

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    YesStability and safety of offshore wind turbines with mono-pile foundations, affected by nonlinear wave effect and dynamic seabed response, are the primary concerns in offshore foundation design. In order to address these problems, the nonlinear wave effect on dynamic seabed response in the vicinity of mono-pile foundation is investigated using an integrated model, developed using OpenFOAM, which incorporates both wave model (waves2Foam) and Biot’s poro-elastic model. The present model was validated against several laboratory experiments and promising agreements were obtained. Special attention was paid to the systematic analysis of pore water pressure as well as the momentary liquefaction in the proximity of mono-pile induced by nonlinear wave effects. Various embedment depths of mono-pile relevant for practical engineering design were studied in order to attain the insights into nonlinear wave effect around and underneath the mono-pile foundation. By comparing time-series of water surface elevation, inline force, and wave-induced pore water pressure at the front, lateral, and lee side of mono-pile, the distinct nonlinear wave effect on pore water pressure was shown. Simulated results confirmed that the presence of mono-pile foundation in a porous seabed had evident blocking effect on the vertical and horizontal development of pore water pressure. Increasing embedment depth enhances the blockage of vertical pore pressure development and hence results in somewhat reduced momentary liquefaction depth of the soil around the mono-pile foundation.Energy Technology Partnership (ETP), Wood Group Kenny, and University of Aberdeen; the National Science Fund for Distinguished Young Scholars (51425901) and the 111 project (B12032)

    Legume-Cereal Intercropping Improves Forage Yield, Quality and Degradability.

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    Intercropping legume with cereal is an extensively applied planting pattern in crop cultivation. However, forage potential and the degradability of harvested mixtures from intercropping system remain unclear. To investigate the feasibility of applying an intercropping system as a forage supply source to ruminants, two consecutive experiments (experiments 1 and 2) involving a field cultivation trial and a subsequent in vivo degradable experiment were conducted to determine the forage production performance and the ruminally degradable characteristics of a harvested mixture from an alfalfa/corn-rye intercropping system. In experiment 1, the intercropping system was established by alternating alfalfa and corn or rye with a row ratio of 5:2. Dry matter (DM) and nutrient yields were determined. In experiment 2, forages harvested from the different treatments were used as feedstuff to identify nutrient degradation kinetics and distribution of components between the rapidly degradable (a), potentially degradable (b) and the degradation rate constant (c) of 'b' fraction by in sacco method in Small-Tail Han wether Sheep. The intercropping system of alfalfa and corn-rye provided higher forage production performance with net increases of 9.52% and 34.81% in DM yield, 42.13% and 16.74% in crude protein (CP) yield, 25.94% and 69.99% in degradable DM yield, and 16.96% and 5.50% in degradable CP yield than rotation and alfalfa sole cropping systems, respectively. In addition, the harvest mixture from intercropping system also had greater 'a' fraction, 'b' fraction, 'c' values, and effective degradability (E value) of DM and CP than corn or rye hay harvested from rotation system. After 48-h exposure to rumen microbes, intercropping harvest materials were degraded to a higher extent than separately degraded crop stems from the sole system as indicated by visual microscopic examination with more tissues disappeared. Thus, the intercropping of alfalfa and corn-rye exhibited a greater forage production potential, and could be applied as forage supply source for ruminants. The improved effective degradability of harvest mixture material could be attributed to greater degradable components involving the rapidly degradable fractions (a), potentially degradable (b) fractions, and degradable rate constan

    Mesoporous Beta Zeolite Catalysts for Benzylation of Naphthalene: Effect of Pore Structure and Acidity

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    To improve the catalytic performance of zeolite catalysts in reactions involving bulky molecules, a series of mesoporous Beta zeolite were prepared using organic functionalized fumed silica as the silicon source, which were thoroughly characterized in terms of porosity and acidity. The peaks in X-ray diffraction (XRD) patterns showed broadening, and the external surface area and mesoporosity increased progressively when the content of organic functionalization increased. An infrared (IR) spectroscopy study of adsorbed probe molecules, including pyridine (Py-IR), 2,6-ditertbutylpyridine (DTBPy-IR) and pivalonitrile (Pn-IR), showed that the improvement of mesoporosity increased the accessibility of acidic sites. In the catalytic benzylation of naphthalene with benzyl chloride (BC) over the mesoporous Beta zeolite catalysts, the conversion of BC was significantly increased when the accessibility of Brönsted acid sites improved. The increase of mesoporosity not only improved the diffusion ability of the reactants and products, but also increased the accessibility of acid sites, which greatly enhanced the activity of the mesoporous Beta zeolite catalysts. It is highlighted that the interdependence of mesoporosity, acid type, acid concentration, and strength of the mesoporous Beta zeolites on the catalytic performance in the benzylation of naphthalene with BC was comprehensively studied

    Wave (Current)-Induced Pore Pressure in Offshore Deposits: A Coupled Finite Element Model

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    The interaction between wave and offshore deposits is of great importance for the foundation design of marine installations. However, most previous investigations have been limited to connecting separated wave and seabed sub-models with an individual interface program that transfers loads from the wave model to the seabed model. This research presents a two-dimensional coupled approach to study both wave and seabed processes simultaneously in the same FEM (finite element method) program (COMSOL Multiphysics). In the present model, the progressive wave is generated using a momentum source maker combined with a steady current, while the seabed response is applied with the poro-elastoplastic theory. The information between the flow domain and soil deposits is strongly shared, leading to a comprehensive investigation of wave-seabed interaction. Several cases have been simulated to test the wave generation capability and to validate the soil model. The numerical results present fairly good predictions of wave generation and pore pressure within the seabed, indicating that the present coupled model is a sufficient numerical tool for estimation of wave-induced pore pressure

    Effects of Clostridium butyricum on breast muscle lipid metabolism of broilers

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    To investigate the effects of Clostridium butyricum (C. butyricum) on breast muscle lipid metabolism of broilers, 192 one-day-old male Arbor Acres broilers were randomly allocated into 2 treatments with 6 replicates in a completely randomised design. The broilers were fed corn-soybean meal-based diets and supplemented with 0 or 1 × 109 cfu of C. butyricum/kg of diet for 42 days. The birds in the C. butyricum-supplemented group showed higher (p < .05) average daily gain during the grower phase and throughout the entire period of the experiment and a lower (p = .047) feed conversion rate during the grower phase. Supplementation with C. butyricum increased (p < .05) the intramuscular fat content, lipoprotein lipase activity and mRNA levels in the breast muscle at 42 days of age, increased (p = .032) the serum insulin level at 21 days of age, and enhanced (p = .020) the caecal Firmicutes relative abundance at 42 days of age. Additionally, supplementation with C. butyricum reduced (p < .05) the serum growth hormone levels at both 21 and 42 days of age, decreased (p < .05) the ileum angiopoietin-like protein 4 (ANGPTL4) mRNA levels and serum ANGPTL4 concentrations at 42 days of age, and decreased (p < .05) the hormone-sensitive lipase activity, carnitine palmitoyltransferase 1, carnitine palmitoyltransferase 2, and long-chain acyl-CoA dehydrogenase mRNA levels in the breast muscle at 42 days of age. In conclusion, dietary supplementation with C. butyricum could potentially target caecal microbiota and reduced the breast muscle fatty acid oxidation of broilers
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