Osteomyelitis jaw

Catedra de chirurgie oro-maxilo-facială „Arsenie Guţan”, USMF ”Nicolae Testemiţanu”During 2006 the department oro-maxillo-facial surgery (ChOMF) were examined and treated 1883 patients. Posttraumatic osteomyelitis was recorded in 59 patients, representing 3.13%. Patients from other districts than Chisinau is 59.32%. In patients without a job in 62.71% more often fracture was complicated by osteomyelitis and 64.4% of cases was made to open the abscess, and in 59.32% cases were addressed independently. After 5 days of illness onset were sent to 32.2%. In 67.8% cases patients received medical insurance. Pe parcursul anului 2006 în secţia Chirurgie oro-maxilo-facială au fost examinaţi şi trataţi 1883 de bolnavi. Osteomielita posttraumatică a fost înregistrată la 59 bolnavi, ce constituie 3,13%. Pacienţii din alte raioane decât Chişinău constituie 59,32%. La pacienţii fără un loc de lucru în 62,71% mai frecvent fractura s-a complicat cu osteomielită şi în 64,4% din cazuri s-a efectuat deschiderea abcesului, iar în 59,32% cazuri s-au adresat sinestătător. După 5 zile de la debutul bolii s-au adresat 32,2%. În 67,8% cazuri pacienţii au asigurare medicală

CONSIDERATIONS ON LIQUID-CHROMATOGRAPHIC SEPARATION FOR AN EQUIMOLAR MIXTURE OF 2,4-DINITROPHENYLHYDRAZONES OF ACETALDEHYDE AND DIACETYL

An equimolar mixture of 2.4-dinitrophenylhidrazones (2.4DNPH-ones) providing by acetaldehyde and diacetyl must be analyzed by liquid-chromatographic separation, using the mechanism of repartition with reverse phase; that full papers is for identification the optimal analytical conditions. As mobile phase are utilized various binary mixtures eluent, containing water and methanol, with 0-45% water. By the experimental studies were identified four domains of behavior and two optimal binary mixtures, with 25% and 45% water, thus this is a study on the behavior of binary mixtures mobile phases. The peaks are characterized by values of retention times and by position. The separation processes were appreciated by difference between the retention times of peaks; if the percent of water increase, the values of retention times is higher. When the percent of water is 45%, the difference between the retention times is maxim, associated with a change of peaks position

THE MIXTURES OF 2.4-DINITROPHENYLHIDRAZONES OF INFERIOR CARBONYL COMPOUNDS AND THEIR HPLC SEPARATION WITH GRADIENT BINARY MIXTURES PHASES

Mixtures of small quantities of carbonyl compounds are presents in foods, concerning sensorial qualities. The inferior carbonyl compounds (C2-C4, boiling point <100°C) – mono and dicarbonyl – can be identified and measured their concentrations, after a separation by distillation on the water bath. They are transferred in a strongly acid solution of 2.4-dinitrophenylhidrazine (2.4-DNPH), generating a mixture of insoluble 2.4-dinitrophenylhidrazones (2.4-DNPH-ones). The 2.4-DNPH-ones are organic compounds with weak polarity, solids, crystallized, yellows and water insoluble, soluble in organic solvents. The mixture of 2.4dinitrophenylhidrazones may be separated by liquid chromatography, using the reverse phase mechanism [1-3]. This paper contains experimental and theoretical considerations to the means of separation through liquid chromatography of two synthetically and a natural mixtures that contain 2.4-DNPH-ones provided by inferior carbonyl compounds; to obtain conclude results, in the synthetically mixtures was introduce and 2.4-DNPH-ones provided by carbonyl compounds having three (acetone and propanal) and four (isobutyl aldehyde) atoms of carbon

PARTICULARITY ON LIQUID CHROMATOGRAPHIC SEPARATION FOR AN EQUIMOLAR MIXTURE OF 2,4-DINITROPHENYLHYDRAZONES PROVIDED BY ACETALDEHYDE AND DIACETYL

An equimolar mixture of 2,4-dinitrophenylhidrazones (2,4-DNPH-ones) providing by acetaldehyde and diacetyl has been analyzed by liquid-chromatographic separation, using the mechanism of partition with reverse phase. As mobile phase are utilized various binary mixtures, containing water (0 – 45%) and methanol. By the experimental studies were identified four domains of behavior and two optimal binary mixtures, containing 25 and 45% water respectively. The peaks are characterized by values of retention time and by position. The separation processes were appreciated by difference between the retention times of peaks; if the percent of water increase, the values of retention times is higher, heaving a maxim value when the percent of water is 25%. For a mixture of mobile phase with 35% water and 65% methanol, the difference between retention time’s values became null; the behavior is comparable with those of pure methanol, but for higher values of retention times. When the percent of water is 45%, the difference between the retention times is also maxim, associated with a change of peaks positions

Wet cough in children: Infective and inflammatory characteristics in broncho-alveolar lavage fluid

Wet cough is a common feature of many disease processes affecting children. Our aim was to examine the relationships between cough nature, lower airway infection (bacterial, viral, and viral-bacterial) and severity of neutrophilic airway inflammation. We hypothesized that viral-bacterial co-infection of the lower airway would be associated with wet cough and heightened neutrophilic airway inflammation. We prospectively recruited 232 children undergoing elective flexible bronchoscopy. Participants were grouped using a cough nature symptom-based approach, into wet, dry or no cough groups. Broncho-alveolar lavage (BAL) and clinical data, including presence, nature, and duration of cough and key demographic factors, were collected. Children with wet cough (n=143) were more likely to have lower airway bacterial infection (OR 2.6, P=0.001), viral infection (OR 2.04, P=0.045) and viral-bacterial co-infection (OR 2.65, P=0.042) compared to those without wet cough. Wet cough was associated with heightened airway neutrophilia (median 19%) as compared to dry or no cough. Viral-bacterial co-infection was associated with the highest median %neutrophils (33.5%) compared to bacteria only, virus/es only and no infection (20%, 18%, and 6%, respectively,

Towards developing a valid scoring tool for bronchitis during flexible bronchoscopy

Background: A valid bronchoscopic scoring tool for bronchitis would be useful for clinical and research purposes as currently there are none in children. From 100 digitally recorded flexible bronchoscopies (FB), we related the various macroscopic features to airway neutrophil % to develop a FB-derived bronchitis score (BScoreexp). We aimed to develop a FB-derived bronchitis tool. Methods: FB recordings for six visualised features: secretions (amount and color) and mucosal appearance (erythema, pallor, ridging, oedema) based on pre-determined criteria on a pictorial chart were assessed by two physicians independently, blinded to the clinical history. These features were used to obtain various models of BScoreexp that were plotted against bronchoalveolar lavage (BAL) neutrophil % using a receiver operating characteristic (ROC) curve. Inter- and intra-rater agreement (weighted-kappa, K) were assessed from 30 FBs. Results: Using BAL neutrophilia of 20% to define inflammation, the highest area under ROC (aROC) of 0.71, 95%CI 0.61-0.82 was obtained by the giving three times weightage to secretion amount and color and adding it to erythema and oedema. Inter-rater K values for secretion amount (K = 0.87, 95%CI 0.73-1.0) and color (K = 0.86, 95%CI 0.69-1.0) were excellent. Respective intra-rater K were 0.95 (0.87-1.0) and 0.68 (0.47-0.89). Other inter-rater K ranged from 0.4 (erythema) to 0.64 (pallor). Conclusion: A repeatable FB-defined bronchitis scoring tool can be derived. However, a prospective study needs to be performed with larger numbers to further evaluate and validate these results