Current conditions and issues at Temporary Education Centres (TECs) for Syrian child refugees in Turkey

Since the outbreak of Syrian conflict 2011, Turkey has received more than 3.5 million refugees, including a great number of school-aged children. Providing education to Syrian child refugees has therefore become important in Turkey. To effectively deal with this issue, Turkish government has developed educational policies and legal arrangements. Establishing Temporary Education Centres providing education in Arabic based on an adapted Syrian curriculum, was one of the main changes in Turkish educational system to accommodate Syrian child refugees. This paper aims to present the current conditions and issues at TECs based on views of Syrian teachers working in these centres. The findings show that TECs have faced several challenges, which can be categorized under three themes: infrastructral, student-related, and teacher-related challenges. The issues related to each of themes are disscussed based on the views of teachers working in TECs and suggestions relevant to both policymakers and researchers are presented in this paper. © 2020, © 2020 Korean Association for Multicultural Education

Examination of Methods Employed in Industrial Archaeology Conservation: Case of Beykoz Leather and Shoe Factory

This paper focuses on examining the transformation of the Beykoz Leather and Shoe Factory area, investigating the qualities of the buildings in the area, and evaluating them in the context of industrial archaeology. The study aimed to determine whether each of the four conservation methods determined by TICCIH and ERIH organizations and Rolf Höhmann (1992) are preferred for the buildings of the Beykoz Leather and Shoe Factory. Data collection was carried out in 5 years between 2018-2022. Data were collected through on-site observation, analysis of relevant documentation, and interviews with the Kundura Hafıza (Shoe Memory) unit established within the factory during multiple site visits. The original aspect and importance of the study is to conduct and comprehensively evaluate all three of the literature study, fieldwork, and data analysis within the scope of the study

Bağımlılıkla Mücadelede Koruyucu ve Önleyici Faktörlerin İncelenmesi: Yaşam Becerilerinin Rolü

Gelişimsel olarak risk grubunda bulunan çocuk ve ergenlerin karşı karşıya kalabileceği bağımlılık türleri içinde madde bağımlılığı önemli bir yer tutmaktadır. Bilindiği gibi bağımlılık noktasında gelişimsel olarak risk altında bulunan çocuk ve ergenlerin karşı karşıya kalabileceği madde bağımlılığına yönelik farklı perspektiflere sahip önleme ve müdahale programları geliştirilmektedir. Bununla birlikte madde bağımlılığını önleme amaçlı programların daha çok bilgilendirmeye dayalı oldukları görülmektedir. Bu çalışmanın amacı ergenlerde madde bağımlılığı ile yaşam becerileri arasındaki ilişkinin belirlenmesidir. Bu doğrultuda madde kullanımına/ bağımlılığına ilişkin olarak ergenlerin ve ailelerinin tutumları, düşünceleri ve başlama hikâyelerinden hareketle maddeye başlanma nedenleri, madde kullanmanın sonuçları ve madde bağımlılığını önlemede yaşam becerilerinin önem ve işlevini ortaya koymak amacıyla nitel bir araştırma yapılmıştır. Araştırmanın verileri odak grup görüşmesi tekniği ile ebeveyn (45 ebeveyn) ve gençlerden (42 genç) oluşan toplam 87 kişi ile 10 ayrı görüşmeden toplanmıştır. Elde edilen verilerin incelenmesi, nitel veri analizi tekniğine uygun olarak geliştirilen MAXQDA programı ile bilgisayar ortamında yapılmıştır Analizler sonucunda madde kullanan ergenlerin aileleri ile sorun yaşadıkları, aileleri ve arkadaşlarıyla ilişkilerinin iyi olmadığı, okul başarılarının ve okula bağlılıklarının düşük olduğu bulguları elde edilmiştir. 4H Yaşam Becerileri Modeli kapsamında yapılan değerlendirmeyle ergenlerin madde kullanımını önlemede etkili olabileceğine inandıkları yaşam becerileri arasında duyuşsal alanda sosyal beceriler, iletişim ve besleyici ilişkiler kurabilme; bilişsel alanda problem çözme, maddeye karşı koyma ve hedef belirleme; sağlık alanında duyguları yönetme ve öz disiplin gibi becerilerin ön plana çıktığı görülmektedir

Projections of climate change in the Mediterranean Basin by using downscaled global climate model outputs

The Mediterranean Basin is one of the regions that shall be affected most by the impacts of the future climate changes on hydrology and water resources. In this study, projected future changes in mean air temperature and precipitation climatology and inter-annual variability over the Mediterranean region were studied. For performing this aim, the future changes in annual and seasonal averages for the future period of 2070-2100 with respect to the period from 1970 to 2000 were investigated. Global climate model outputs of the World Climate Research Program's Coupled Model Intercomparison Project Phase 3 multi-model dataset were used in this work. Intergovernmental Panel on Climate Change SRES A2, A1B and B1 emission scenarios' outputs were used in future climate model projections. Future surface mean air temperatures of the larger Mediterranean basin increase mostly in summer and least in winter, and precipitation amounts decrease in all seasons at almost all parts of the basin. Future climate signals for air temperature and total precipitation values are much larger than the inter-model standard deviation. Inter-annual temperature variability increases evidently in summer season and decreases in the northern part of the domain in the winter season, while precipitation variability increases in almost all parts of domain. Probability distribution functions are found to be shifted and flattened for future period compared to the reference period. This indicates that the occurrence of frequency and intensity of high temperatures and heavy precipitation events will likely increase in the future period

Investigation of metabolic effects of CETP gene rs289714 variation in coronary artery patients: A case-control study

Objective: The aim of this study was to investigate the effects of the CETP gene rs289714 polymorphism on the serum lipid profile and other metabolic parameters in Turkish patients with coronary artery disease (CAD)

Protective and Preventative Factors in Struggling with Addiction: The Role of Life Skills

WOS: 000503273200018Drug addiction plays an important role in the problems experienced by children and adolescents in developmental risk groups. The programs developed to prevent drug addiction seem to be more on knowledge level. The aim of this study is to determine the relationship between drug addiction and life skills in adolescents. In this context, a qualitative research has been conducted in order to demonstrate the attitudes of young people and their families towards substance use/dependence, the motivations of considering and starting narratives. the reasons of starting to drug, the consequences of drug use and the importance of life skills in preventing drug addiction. The data were gathered from 10 separate interviews with a total of 87 people, consisting of parents; (45) and young people (42) with the focus group interviews. The data were analyzed with qualitative data analysis technique using MAXQDA program. As a result of the research, it is found that young people who use drugs have problems with their families, do not have good relations with their families and friends, and they have low school achievement and school loyalty. Among the life skills that young people believe to be effective in preventing drug use are social skills, communication and nurturing relationships in affective domain; , problem solving, resistance to substance and goal setting, health in the field of managing emotions and self-discipline are the most important ones in cognitive domain

ETS-domain transcription factor Elk-1 mediates neuronal survival: SMN as a potential target

AbstractElk-1 belongs to the ternary complex factors (TCFs) subfamily of the ETS domain proteins, and plays a critical role in the expression of immediate-early genes (IEGs) upon mitogen stimulation and activation of the mitogen-activated protein kinase (MAPK) cascade. The association of TCFs with serum response elements (SREs) on IEG promoters has been widely studied and a role for Elk-1 in promoting cell cycle entry has been determined. However, the presence of the ETS domain transcription factor Elk-1 in axons and dendrites of post-mitotic adult brain neurons has implications for an alternative function for Elk-1 in neurons other than controlling proliferation. In this study, possible alternative roles for Elk-1 in neurons were investigated, and it was demonstrated that blocking TCF-mediated transactivation in neuronal cells leads to apoptosis through a caspase-dependent mechanism. Indeed RNAi-mediated depletion of endogenous Elk-1 results in increased caspase activity. Conversely, overexpression of either Elk-1 or Elk-VP16 fusion proteins was shown to rescue PC12 cells from chemically-induced apoptosis, and that higher levels of endogenous Elk-1 correlated with longer survival of DRGs in culture. It was shown that Elk-1 regulated the Mcl-1 gene expression required for survival, and that RNAi-mediated degradation of endogenous Elk-1 resulted in elimination of the mcl-1 message. We have further identified the survival-of-motor neuron-1 (SMN1) gene as a novel target of Elk-1, and show that the ets motifs in the SMN1 promoter are involved in this regulation

Contribution of functionally assessed GHRHR mutations to idiopathic isolated growth hormone deficiency in patients without GH1 mutations

International audienceIsolated growth hormone deficiency (IGHD) is a rare condition mainly caused by mutations in GH1. The aim of this study was to assess the contribution of GHRHR mutations to IGHD in an unusually large group of patients. All GHRHR coding exons and flanking intronic regions were sequenced in 312 unrelated patients with nonsyndromic IGHD. Functional consequences of all newly identified missense variants were assessed in vitro (i.e., study of the expression of recombinant GHRHRs and their ability to activate the cyclic adenosine monophosphate (cAMP) signaling pathway). Genotype-phenotype correlation analyses were performed according to the nature of the identified mutation. We identified 20 different disease-causing GHRHR mutations (truncating and missense loss-of-function mutations), among which 15 are novel, in 24 unrelated patients. Of note, about half (13/24) of those patients represent sporadic cases. The clinical phenotype of patients with at least one missense GHRHR mutation was found to be indistinguishable from that of patients with bi-allelic truncating mutations. This study, which unveils disease-causing GHRHR mutations in 8% (24/312) of IGHD cases, identifies GHRHR as the second IGHD gene most frequently involved after GH1. The finding that 8% of IGHD cases without GH1 mutations are explained by GHRHR molecular defects (including missense mutations), together with the high proportion of sporadic cases among those patients, has important implications for genetic counseling

Contribution of Functionally Assessed GHRHR Mutations to Idiopathic Isolated Growth Hormone Deficiency in a Cohort of 312 Unrelated Patients

International audienc