Serum lipid profile and obesity scanning of a group of primary school students in central villages of mugla province

Vücutta yag dokusunun asırı artmasına obezite denir. Obezite; bütün yas gruplarında, ırk ve etnik gruplarda görülen yaygın bir saglık problemi olup, 20. yüzyılda eriskinlerde oldugu kadar çocuklarda da büyük bir saglık sorunu olarak karsımıza çıkmaktadır. Bu çalısma, Mugla'nın merkez köylerindeki 7-15 yas arası ilkögretim okulu ögrencilerinde lipid profili ve obezite durumunu belirlemek amacıyla yapılmıstır. Bu çalısmada;Mugla'nın 9 merkez köyündeki ilkögretim okullarında okuyan toplam 231(112 kız, 119 erkek) ögrencinin yas, cinsiyet, boy ve kilo bilgileri toplandı, vücut kitle indeksleri(VKI) hesaplandı ve açlık kanları alınarak enzimatik-kolorimetrik yöntemle Total Kolesterol(TK), Trigliserid(TG), HDL-, LDL- ve VLDL-Kolesterol (HDL, LDL,VLDL, sırasıyla) ölçümleri yapıldı. Sonuçlar; tüm ögrencilerin %6.5'inin zayıf (VKI<=5), %69.3'ünün normal (VKI=5-85), %11.2'sinin fazla kilolu (VKI=85-95) ve %13.0'ünün obez (VKI>=95) oldugunu gösterdi.Kız ve erkek gruplar arasındaVKI yönünden önemli fark yoktu (p>0.05). Yapılan hesaplamalarda, tüm lipid parametreleri (TK,TG,HDL,LDL,VLDL) için kız ve erkek gruplar arasında istatistiksel olarak önemli bir fark bulunamadı (p>0.05). Serum lipid parametrelerinin VKI'ne göre yapılan karsılastırmalarında; TG ve VLDL degerlerinin zayıf grupta, TK ve LDL degerlerinin ise normal grupta diger gruplara göre daha düsük oldugu (her ikisi için de p<0.05) bulundu. Zayıf grubun HDL degerleri, diger gruplara göre istatistiksel bakımdan önemli derecede yüksek idi (p<0.01)AyrıcaTVizlerken bir seyler atıstıran çocuklarınTKdüzeyleri, yemeyen çocuklara göre daha yüksek bulunurken (p0.05). Yanlıs beslenme alıskanlıklarına ve sedanter yasam kosullarına baglı olarak gelisen obeziteye paralel sekilde kan lipid parametrelerinde de olumsuz degisiklikler meydana gelmektedir. Çocukluk döneminde gelisen bu olumsuz tablo düzeltilmedigi takdirde, obeziter yapı yasamın ileriki yıllarına da tasınmakta ve buna baglı saglık sorunları giderek artmaktadır.Obesity is referred to as an excessive increase in lipid tissue of body. This study was aimed to determine lipid profile and obesity-related conditions of primary school students between ages 7 and 15 in central villages of Mugla Province. In the present study, age, sex, height and weight demographics of 231 (112 girls, 119 boys) students attending primary schools located in 9 central villages of Mugla Province were gathered, their body mass indexes (BMI) were calculated, and total cholesterol (TC), triachylglicerol (TG), and HDL-, LDL-, and VLDL-Cholesterol levels were measured in fasting blood samples. Of all students, 6.5% were lean (BMI<=5), 69.3% were normal (BMI=5-85), 11.2% were overweight (BMI=85-95) and 13.0 were obese (BMI>=95). There was no significant difference between girls and boys with respect to the BMI (p>0.05). No statistically significant difference could be found between groups of girls and boys in any of the lipid parameter (TC,TG,HDL,LDL,VLDL) calculations (p>0.05). It was found that TG and VLDL values were relatively low in lean group, however TC and LDL values were lower in normal group in comparison with those of the other groups (for both p<0.05). There was no significant difference between groups concerning HDL-C (p>0.05). Moreover, whereas TC levels of children, who snack while watching television were found to be higher than those of children who do not snack (p<0.05), the difference between other parameters was statistically insignificant (p>0.05). Because of wrong dietary habits and sedentary life, obesity developes followed by blood lipid abnormalities. If these are not corrected in childhood obesity will result in increasingly serious health problems

Recent Advances in Health Biotechnology During Pandemic

The outbreak of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which emerged in 2019, cut the epoch that will make profound fluctuates in the history of the world in social, economic, and scientific fields. Urgent needs in public health have brought with them innovative approaches, including diagnosis, prevention, and treatment. To exceed the coronavirus disease 2019 (COVID-19) pandemic, various scientific authorities in the world have procreated advances in real time polymerase chain reaction (RT-PCR) based diagnostic tests, rapid diagnostic kits, the development of vaccines for immunization, and the purposing pharmaceuticals for treatment. Diagnosis, treatment, and immunization approaches put for- ward by scientific communities are cross-fed from the accrued knowledge of multidisciplinary sciences in health biotechnology. So much so that the pandemic, urgently prioritized in the world, is not only viral infections but also has been the pulsion in the development of novel approaches in many fields such as diagnosis, treatment, translational medicine, virology, mi- crobiology, immunology, functional nano- and bio-materials, bioinformatics, molecular biol- ogy, genetics, tissue engineering, biomedical devices, and artificial intelligence technologies. In this review, the effects of the COVID-19 pandemic on the development of various scientific areas of health biotechnology are discussed

Effects of Treatment on Angiogenic (Vascular Endothelial Growth Factor-2 and Matrix Metalloproteinase-2) and Antiangiogenic (Endostatin and Thrombospondin-1) Factors in Non-muscle Invasive Bladder Carcinoma

Objective: We aimed to investigate possible effects of treatment on angiogenic [vascular endothelial growth factor-2 (VEGF-2) and matrix metalloproteinase-2 (MMP-2)] and antiangiogenic [endostatin (ES) and thrombospondin-1 (TSP-1)] factors in non-muscle invasive bladder carcinoma (NMIBC). Materials and Methods: Thirty NMIBC patients and 30 age-matched controls were included in the study. For the above-mentioned markers, peripheral blood samples were drawn at three time points to be studied by enzyme-linked immunosorbent assay: before transurethral resection of bladder tumor (TURBT), at first control (20 days after the operation) and second control (at the end of intravesical immunotherapy). The mean blood levels obtained in the three measurements and those in patients and controls were compared statistically. Results: The mean levels of VEGF-2 and MMP-2 in patients before TURBT were found to be statistically significantly higher than in controls (p=0.04 and p=0.01, respectively), while no significant differences were obtained between the mean ES and TSP-1 levels (p=0.95 and p=0.99, respectively). It was also found that the VEGF-2 and MMP-2 levels were significantly decreased after TURBT (p=0.03 and p=0.01, respectively), but the tendency of these decrease was not found to be statistically significant between the first and second controls. Conclusion: Elevated VEGF-2 and MMP-2 levels in patients with NMIBC were significantly decreased after and probably due to the TURBT, which leads to a conclusion that these angiogenic markers may be used for follow-up of NMIBC

Geological analysis of Çınarcık basın and surroundings: tectonic and palaeoclimatic properties, Eastern Marmara

Maden Tetkik ve Arama Genel Müdürlüğü tarafından inşa ettirilen ve 2017 yılı başında denizlerimizde çalışmaya başlayacak olan MTA Araştırma Gemisi (Turkuaz) birçok alanda bilimsel çalışma yapabilme yeteneğine sahip ve ülkemizin önemli değerlerinden biri olacaktır. Bu nedenle hem ulusal hem de uluslararası bilimsel çalışmalar için gerekli hazırlıklar yapılmaya başlanmıştır. Bu amaçla 2017-2018 yılları arasında gerçekleştirilmesi planlanan ve test deneme çalışmaları ile eş zamanlı yürütülecek olan söz konusu proje üç önemli çalışma planından oluşmaktadır. Bunlar; (1) Doğu Marmara’da bulunan Prens Adaları civarından alınacak karotlar sayesinde şelf alanına ait paleoiklimsel koşulların araştırılması, (2) Doğu Marmara’da bulunan Çınarcık Havzası içinde KAFS’nin yayılımının tespit edilmesi için K-G ve D-G yönde sismik profiller alınarak aynı zamanda deniz tabanı morfolojisinin çıkarılması ve (3) Çınarcık Havzası depolanma merkezinden alınacak karotlar sayesinde sismo-türbiditlerin ve eski depremlere ait izlerin araştırılması hedeflenmektedir. Bu kapsamda 2016 yılı sonunda projenin hedeflerinden ilki olan Prens Adalar bölgesinden 12 adet, yaklaşık 20-100 m su derinliklerinden, her biri 1,5 m uzunluğunda karot örnekleri MTA Selen Araştırma Gemisi ile alınmıştır. Bu karotlardan 12 tanesi Çok Sensörlü Karot Loglayıcı (MSCL) ve 4 tanesi ITRAX cihazı ile İTÜ, EMCOL Laboratuvarında analiz edilmiştir. Bunun yanında yine MTA Araştırma Gemileri (Selen ve Turkuaz) ile sismik veriler toplanacak ve bölgenin yapısal özellikleri belirlenmeye çalışılacaktır. Son olarak, MTA Araştırma Gemisi’nin (Turkuaz) hizmete girmesine müteakip 2017 yılı içinde Çınarcık Havzası depolanma merkezinden derin karotlar alınarak eski depremlere ait kayıtların araştırılması planlanmaktadır. Kurultay katılımcılarına proje kapsamında şu ana kadar yapılmış olan literatür çalışmaları, Prens Adaları civarından alınan ve analiz edilen karotların ilk bulguları ve yapılması planlanan çalışmalar hakkında ayrıntılı bilgiler sunulacaktır.The MTA Research Ship (Turkuaz), which was built by the General Directorate of Mineral Research and Exploration and will start to work in our seas at the beginning of 2017, has the ability to carry out many scientific studies and it will be one of the important values of our country. For this reason, required preparations have been started making for both national and international scientific studies. For this purpose, the project which is planned to be applied between 2017-2018 years and will be carried out simultaneously with the test trial works consists of three important remarks. These are; (1) to investigate the paleoclimatic conditions of the shelf area due to the cores to be taken from the Prince Islands area in the Eastern Marmara, (2) limited seismic profiles were taken in N-S and E-W direction to define the propagation of the KAFS in the Çınarcık Basin in the Eastern Marmara and sea floor morphology will be determined, (3) it is also aimed to investigate the seismo-turbidites of the previous earthquakes by using the cores to be taken from the depocenter of the Çınarcık Basin. In this context, 12 cores with approximately 20-100 m water depth, 1,5 m in length were taken from the Prince Islands area which is the first step of project with MTA Selen Research Ship. 12 of these cores were analyzed with Multi-Sensor Core Logger (MSCL) and 4 of them were analyzed with ITRAX in ITU, EMCOL Laboratory. In addition, a limited number of seismic data are collected with the MTA Research Ships (Selen and Turkuaz) and will continue to work again when weather conditions are favorable. Furthermore, it is planned in 2017 to apply the studies belonging to previous earthquakes by taking deep cores from the depocenter of Çınarcık Basin after the coming of MTA Research Ship (Turkuaz). For participants of Congress, detailed information about the literature studies, preliminary results of the core analyses around Prince Islands area and future plans will be provided