1,052 research outputs found
IRAF and STSDAS under the new ALPHA architecture
Digital's next generation RISC architecture, known as ALPHA, presents many IRAF system portability questions and challenges to both site managers and end users. DEC promises to support the ULTRIX, VMS, and OSF/1 operating systems, which should allow IRAF to be ported to the new architecture at either the program executable level (using VEST), or at the source level, where IRAF can be tuned for greater performance. These notes highlight some of the details of porting IRAF to OpenVMS on the ALPHA architecture
Sub-Plate Overlap Code Documentation
An expansion of the plate overlap method of astrometric data reduction to a single plate has been proposed and successfully tested. Each plate is (artificially) divided into sub-plates which can then be overlapped. This reduces the area of a 'plate' over which a plate model needs to accurately represent the relationship between measured coordinates and standard coordinates. Application is made to non-astrographic plates such as Schmidt plates and to wide-field astrographic plates. Indeed, the method is completely general and can be applied to any type of recording media
Posterior Tibial Nerve Stimulation for the Treatment of Fecal Incontinence Following Obstetric Anal Sphincter Injury
OBJECTIVES: Obstetric anal sphincter injuries (OASI) are a major risk factor for fecal incontinence (FI). Neuromodulation is often used as second-line therapy for FI, but evidence for its efficacy is conflicting. We aimed to evaluate the efficacy and predictive factors of posterior tibial nerve stimulation for obstetric anal sphincter injury-induced FI. MATERIALS AND METHODS: Consecutive females with FI related to past OASI who had not responded to first-line therapy and had received 8-12 weeks of posterior tibial nerve stimulation were included. Subjects aged more than 50 and/or having other causes of FI were excluded. Patients underwent anorectal physiology and endoanal ultrasound pretherapy. Symptom burden was evaluated pretherapy and posttherapy using Rockwood and Wexner scales. A Wexner score reduced to below 10 or halved was used to define responders. RESULTS: A total of 37 females (mean age 38 years, median parity 2) were included. About 17 (46%) had ultrasonographically visualized anal sphincter defects and 41% had a history of third or second-degree perineal tears. About 14 subjects (38%) were deemed responders. Compared with nonresponders, responders had lower baseline rectal distension thresholds and tended to have disrupted (59%) than intact sphincters (20%, p < 0.01). Responders demonstrated improvement in Rockwood score for depression and embarrassment, visual analogue score for bowel symptoms and stool consistency (median baseline Bristol score 5, to 3 posttherapy; p < 0.01). CONCLUSIONS: Of a well-defined cohort of females with FI secondary to OASI, 38% responded to posterior tibial nerve stimulation. Much of this improvement may relate to improvement in stool consistency
Antidepressant efficacy of cariprazine in bipolar disorder and the role of its pharmacodynamic properties:A hypothesis based on data
The treatment of bipolar depression is one of the most challenging needs in contemporary psychiatry. Currently, only quetiapine, olanzapine-fluoxetine combination, lurasidone, cariprazine, and recently lumateperone have been FDA-approved to treat this condition. The neurobiology of bipolar depression and the possible targets of bipolar antidepressant therapy remain elusive. The current study investigated whether the pharmacodynamic properties of cariprazine fit into a previously developed model which was the first to be derived based on the strict combination of clinical and preclinical data. The authors performed a systematic review of the literature to identify the pharmacodynamic properties of cariprazine. The original model suggests that a constellation of effects on different receptors is necessary and that serotonin reuptake inhibition does not appear to play a significant role in acute bipolar depression. On the contrary, norepinephrine activity seems to be necessary. Probably the early antidepressant effect can be achieved through an agonistic activity at 5HT-1A and antagonism at alpha1 noradrenergic and 5-HT2A receptors, but the presence of a norepinephrine reuptake inhibition appears essential to sustain it. Overall, the properties of cariprazine fit well the proposed model and add to its validity. A point that needs further clarification is norepinephrine reuptake inhibition which is not yet fully studied for cariprazine.</p
Análisis del ausentismo en Mundigramas S.A.S para el desarrollo de un programa de mitigacion de Riesgos
Proponer un programa de mitigación de riesgos en Mundigramas S.A.S mediante la evaluación de las causas asociadas al ausentismo laboral en el periodo de 01 de enero de 2015 a 31 de diciembre del 2017La investigación realizada en este proyecto, está basada en la identificación y evaluación de los costos ocultos causados por el ausentismo laboral en el grupo de trabajadores de Mundigramas S.A.S en el periodo del 01 de Enero de 2015 a 31 de Diciembre del 2017.
El resultado de los primeros objetivos de esta investigación determinaranlas causas y los factores que generan el ausentismo en Mundigramas S.A.S; permitiendo establecer un rankig y calcular indicadoresmás importantes para que la alta gerencia , en conjunto con el equipo de SST, establezcanmedidas de intervención detipo preventivo y xxx que de esta manera con la implementación del programa de mitigación se de tratamiento y control alas patologías sufridas por el personal de estudio, teniendo en cuenta que la socialización de las primeras causas de ausentismo en forma individual y colectiva, permiten el conocimientode sus patologías y las formas de prevenirlas para un futuro.
El estudio realizadoes de tipo cualitativoycuantitativo donde participaron32 trabajadores, entre administrativos y operarios, de Mundigramas S.A.S teniendocomo criterio de inclusión las incapacidadespresentadas durante el periodo 01 de Enero de 2015 a 31 de Diciembre del 2017.A partir de los resultados obtenidos, será posible el planteamiento de programas que vayan orientados hacia la mejora en el diseño de los planes de gestión del ausentismo, impulsados por el Ministerio de Salud y sus organismo
Análisis del ausentismo en Mundigramas S.A.S para el desarrollo de un programa de mitigacion de Riesgos
Proponer un programa de mitigación de riesgos en Mundigramas S.A.S mediante la evaluación de las causas asociadas al ausentismo laboral en el periodo de 01 de enero de 2015 a 31 de diciembre del 2017La investigación realizada en este proyecto, está basada en la identificación y evaluación de los costos ocultos causados por el ausentismo laboral en el grupo de trabajadores de Mundigramas S.A.S en el periodo del 01 de Enero de 2015 a 31 de Diciembre del 2017.
El resultado de los primeros objetivos de esta investigación determinaranlas causas y los factores que generan el ausentismo en Mundigramas S.A.S; permitiendo establecer un rankig y calcular indicadoresmás importantes para que la alta gerencia , en conjunto con el equipo de SST, establezcanmedidas de intervención detipo preventivo y xxx que de esta manera con la implementación del programa de mitigación se de tratamiento y control alas patologías sufridas por el personal de estudio, teniendo en cuenta que la socialización de las primeras causas de ausentismo en forma individual y colectiva, permiten el conocimientode sus patologías y las formas de prevenirlas para un futuro.
El estudio realizadoes de tipo cualitativoycuantitativo donde participaron32 trabajadores, entre administrativos y operarios, de Mundigramas S.A.S teniendocomo criterio de inclusión las incapacidadespresentadas durante el periodo 01 de Enero de 2015 a 31 de Diciembre del 2017.A partir de los resultados obtenidos, será posible el planteamiento de programas que vayan orientados hacia la mejora en el diseño de los planes de gestión del ausentismo, impulsados por el Ministerio de Salud y sus organismo
Adubação verde no crescimento e na produção de Schinus terebinthifolius, Hibiscus sabdariffa e Jacaranda decurrens.
bitstream/item/68608/1/005-moreira-adubacao.pdfPublicado também no Cadernos de Agroecologia, v. 7, n.2, 2012
Lethal and Sublethal Effects of Methoxyfenozide on the Development, Survival and Reproduction on of the Fall Armyworm, Spodoptera frugiperda (J. E. Smith) (Lepidoptera: Noctuidae)
The lethal and sublethal effects of the ecdysone agonist methoxyfenozide on the fall armyworm, Spodoptera frugiperda (J. E. Smith), were investigated by feeding a methoxyfenozide-treated diet to fifth instars until pupation in doses corresponding to the LC10 and LC25 for the compound. Larval mortality reached 8% and 26% in the low and high concentration groups, respectively, on the seventh day of the experiment. A progressive larval mortality of 12% for the LC10 and 60% for the LC25 was observed before pupation. Treated larvae exhibited lower pupal weights, higher pupal mortality, presence of deformed pupae, and more deformed adults than untreated larvae. The incorporation of methoxyfenozide into the diet had a significant effect on the timing of larval development. The development period for males and females was about seven days longer than the controls for both concentrations tested. In contrast, the compound affected neither pupae nor adult longevity. Finally, S. frugiperda adults that resulted from fifth instars treated with methoxyfenozide were not affected in their mean cumulative number of eggs laid per female (fecundity), nor percentages of eggs hatched (fertility), or the sex ratio. Our results suggest that the combination of lethal and sublethal effects of methoxyfenozide may have important implications for the population dynamics of the fall armyworm
Frequencies of Salmonella enterica in growing pigs in Paraguay
The objective of this study was to (1) estimate frequencies of Salmonella enterica in growing pigs and (2) investigate farmers' perception and practices towards pig farming in Central Department, Paraguay. Twelve out of 19 districts in the department were selected and 33 farms with growers in the selected districts were recruited. Questionnaire interviews for each study farm, in combination with faecal sample collections (n = 30 per farm), which were microbiologic ally examined and visual inspection of pig production facilities were performed between March and November 2009. A questionnaire was designed to obtain basic information of a farm such as the number of pigs owned and some selected farming management practices. Faecal samples were used for Salmonella isolation, using buffered peptone water to have salmonellae pre-enriched, followed by xylose lysine tergitol 4 agar and brilliant green sulfapyridine agar. Suspect colonies were bio chemically tested by triple sugar iron agar in combination with lysine iron agar to confirm the identity. The true frequency probability and associated 95% Bayesian credible intervals (95% BCI) were computed via the Gibbs sampler, a Markov chain Monte Carlo technique. Overall, 18% (95% BCI: 8-31%) of the tested 1000 faecal samples were classified as positive for Salmonella enterica. All the study farms had at least one positive sample for Salmonella enterica (frequency range: 3-60%). Apparent prevalence at farm-level was therefore 100% (one-sided 97.5% confidence limit: 89%). Twenty-eight different serovars for Salmonella enterica were found. Based on increase the number of study districts, farms as well as animals in combination with improvement of sampling methods, possible spatial differences and risk factors/indicators should be clarified by further investigations.Facultad de Ciencias Veterinaria
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