Management Control, International Observatory 2012

International audienc

Effect of waste glass (TV/PC cathodic tube and screen) on technological properties and sintering behaviour of porcelain stoneware tiles

In the present work, the effects of TV and PC cathodic tube and screen glasses additions (5 and 10 wt.%) to a porcelain stoneware body, in replacement of feldspar, were evaluated simulating the tilemaking process. The presence of glass allows to preserve good technological and mechanical properties, complying with the latest requirements of the industrial practice. The sintering pattern of the glass-added bodies, evaluated by hot stage microscopy, is modified according to the different glass amount and typology; in particular, cathodic tube glass when present at 5 wt.% brings about a lowering of the maximum densification temperature and of the activation energy

Effectively four-dimensional spacetimes emerging from d=5 Einstein-Gauss-Bonnet Gravity

Einstein-Gauss-Bonnet gravity in five-dimensional spacetime provides an excellent example of a theory that, while including higher-order curvature corrections to General Relativity, still shares many of its features, such as second-order field equations for the metric. We focus on the largely unexplored case where the coupling constants of the theory are such that no constant-curvature solution is allowed, leaving open the question of what the vacuum state should then be. We find that even a slight deviation from the anti-de Sitter Chern-Simons theory, where the vacuum state is five-dimensional AdS spacetime, leads to a complete symmetry breakdown, with the fifth dimension either being compactified into a small circle or shrinking away exponentially with time. A complete family of solutions, including duality relations among them, is uncovered and shown to be unique within a certain class. This dynamical dimensional reduction scenario seems particularly attractive as a means for higher-dimensional theories to make contact with our four-dimensional world.Comment: 9 pages, 4 figures. v2: New section on geometrical significance of solutions. Final version for CQ

Reply to the comment by D. Kreimer and E. Mielke

We respond to the comment by Kreimer et. al. about the torsional contribution to the chiral anomaly in curved spacetimes. We discuss their claims and refute its main conclusion.Comment: 9 pages, revte

ERADICAZIONE DI INFEZIONE DA HCV DOPO TRATTAMENTO DI 8 SETTIMANE CON GRAZOPREVIR/ELBASVIR: CASE REPORT

INTRODUZIONE. Il genotipo 1b è il più comune sottotipo di HCV, responsabile del 22% delle infezioni a livello globale. La combinazione di grazoprevir ed elbasvir, assunta una volta al giorno per 12 settimane, ha dimostrato buona tollerabilità ed efficacia (>95%) nell’ottenimento della risposta virologia sostenuta a 12 settimane (SVR12), in pazienti con genotipo 1 e 4, sia naïve che treatment experienced, coinfetti HIV, senza cirrosi o con cirrosi compensata. Secondo le linee guida EASL, sulla base dei dati dello studio STREAGER, è possibile trattare i pazienti naïve con genotipo 1b e grado di fibrosi F0-F2 per 8 settimane. OBIETTIVO. Descrizione di un caso di eradicazione di infezione da HCV in paziente con grado di fibrosi F0-F1 dopo trattamento di 8 settimane con grazoprevir/elbasvir CASO CLINICO. Paziente di anni 67, giunge alla nostra attenzione per intraprendere trattamento per infezione da HCV, riferita esser nota dal 1984; in anamnesi cardiomiopatia dilatativa ipocinetica, ipertensione, angioma cavernoso epatico, litiasi colecistica multipla. Agli esami ematochimici al basale da segnalare ipergammaglobulinemia (21,1%), normale funzionalità epatica, crioglobuline negative, positività degli anticorpi antiDNA nativo, giudicata di non rilevanza clinica da parere reumatologico; test HIV negativo, pregressa HAV, negativi markers per HBV e sierologia per sifilide, HCV RNA 2.750.000 UI/ml, genotipo 1b, grado di fibrosi F0-F1 secondo Metavir. Viene intrapresa terapia con grazoprevir/elbasvir in data 19/03/19; a 4 settimane HCV RNA non rilevabile. Il paziente viene ricoverato in altro nosocomio per colecistite acuta pertanto non si presenta a ritirare l’ultima confezione di farmaco e sospende terapia in data 14/05/2019. Ad un mese dalla sospensione torna a controllo, riferendo aderenza completa nelle 8 settimane di assunzione del farmaco; esegue nella stessa data prelievo ematico, ripetuto a 8 e 12 settimane dal termine della terapia, con riscontro di ematochimica nei limiti e HCV RNA non rilevabile. In programma follow up clinico, laboratoristico ed ecografico semestrale. CONCLUSIONI. Nonostante l’interruzione precoce della terapia, 8 settimane di trattamento con grazoprevir/elbasvir hanno comunque permesso di ottenere una risposta virologica sostenuta (SVR12) in paziente con basso grado di fibrosi e multiple comorbosità nella real life, confermando i dati della letteratura recente

EFFICIENCY OF VIRAL CONCENTRATION IN FOOD SAMPLES: COMPARISON BETWEEN PEG AND ULTRAFILTRATION TECHNIQUES

Norovirus is the most prevalent causative agent of foodborne diseases. However, the detection of this virus in foods other than shellfish is often time-consuming and unsuccessful. The objective of this study is to compare PEG and ultrafiltration techniques for viral concentration in bivalve molluscs. An experiment with Coxsackie B5 and feline Calicivirus strain F is conduct to determine the efficiency of each virus concentration. Ultrafiltration technique is the most indicated

Conformally dressed black hole in 2+1 dimensions

A three dimensional black hole solution of Einstein equations with negative cosmological constant coupled to a conformal scalar field is given. The solution is static, circularly symmetric, asymptotically anti-de Sitter and nonperturbative in the conformal field. The curvature tensor is singular at the origin while the scalar field is regular everywhere. The condition that the Euclidean geometry be regular at the horizon fixes the temperature to be $T=\frac{9\, r_+}{16\pi l^2}$. Using the Hamiltonian formulation including boundary terms of the Euclidean action, the entropy is found to be $\frac{2}{3}$ of the standard value ($\frac{1}{4} A$), and in agreement with the first law of thermodynamics.Comment: LaTeX ,RevTeX, 13pages, no figure

Ebv-driven lymphoproliferative disorders and lymphomas of the gastrointestinal tract: A spectrum of entities with a common denominator (part 2)

Epstein–Barr virus (EBV) is a common pathogen infecting people primarily early in life. The virus has the ability to persist throughout a person’s life, usually in B lymphocytes. Conditions of immunodeficiency as well as the introduction of immunosuppressive therapies and the advent of transplant technologies has brought immunodeficiency-associated lymphoproliferative disorders into view, which are often driven by EBV. The group of EBV-associated lymphoproliferative disorders includes different entities, with distinct biological features, ranging from indolent disor-ders, which may even spontaneously regress, to aggressive lymphomas requiring prompt and ade-quate treatment. These disorders are often diagnostically challenging due to their overlapping mor-phology and immunophenotype. Both nodal and extra-nodal sites, including the gastrointestinal tract, may be involved. This review, divided in three parts, summarizes the clinical, pathological, molecular features and treatment strategies of EBV-related lymphoproliferative disorders occurring in the gastrointestinal tract and critically analyzes the major issues in the differential diagnosis. In this part of the review, we discuss plasmablastic lymphoma, extra-cavitary primary effusion lymphoma and Burkitt lymphoma

Conserved charges for gravity with locally AdS asymptotics

A new formula for the conserved charges in 3+1 gravity for spacetimes with local AdS asymptotic geometry is proposed. It is shown that requiring the action to have an extremum for this class of asymptotia sets the boundary term that must be added to the Lagrangian as the Euler density with a fixed weight factor. The resulting action gives rise to the mass and angular momentum as Noether charges associated to the asymptotic Killing vectors without requiring specification of a reference background in order to have a convergent expression. A consequence of this definition is that any negative constant curvature spacetime has vanishing Noether charges. These results remain valid in the limit of vanishing cosmological constant.Comment: 5 pages, 2 Columns, revtex. Last version for Phys. Rev. Let