Deformations of coisotropic submanifolds for fibrewise entire Poisson structures

We show that deformations of a coisotropic submanifold inside a fibrewise entire Poisson manifold are controlled by the $L_\infty$-algebra introduced by Oh-Park (for symplectic manifolds) and Cattaneo-Felder. In the symplectic case, we recover results previously obtained by Oh-Park. Moreover we consider the extended deformation problem and prove its obstructedness

Deformations of Lagrangian submanifolds in log-symplectic manifolds

This paper is devoted to deformations of Lagrangian submanifolds contained in the singular locus of a log-symplectic manifold. We prove a normal form result for the log-symplectic structure around such a Lagrangian, which we use to extract algebraic and geometric information about the Lagrangian deformations. We show that the deformation problem is governed by a DGLA, we discuss whether the Lagrangian admits deformations not contained in the singular locus, and we give precise criteria for unobstructedness of first order deformations. We also address equivalences of deformations, showing that the gauge equivalence relation of the DGLA corresponds with the geometric notion of equivalence by Hamiltonian isotopies. We discuss the corresponding moduli space, and we prove a rigidity statement for the more flexible equivalence relation by Poisson isotopies

Deformations of symplectic foliations

We develop the deformation theory of symplectic foliations, i.e. regular foliations equipped with a leafwise symplectic form. The main result of this paper is that each symplectic foliation has an attached $L_\infty$-algebra controlling its deformation problem. Indeed, viewing symplectic foliations as regular Poisson structures, we establish a one-to-one correspondence between the small deformations of a given symplectic foliation and the Maurer-Cartan elements of the associated $L_\infty$-algebra. Using this, we show that infinitesimal deformations of symplectic foliations can be obstructed. Further, we relate symplectic foliations with foliations on one side and with (arbitrary) Poisson structures on the other, showing that obstructed infinitesimal deformations of the former may give rise to unobstructed infinitesimal deformations of the latter

Sequence-aware intrusion detection in industrial control systems

Nowadays, several threats endanger cyber-physical systems. Among these systems, industrial control systems (ICS) operating on critical infrastructures have been proven to be an attractive target for attackers. The case of Stuxnet has not only showed that ICSs are vulnerable to cyber-attacks, but also that some of these attacks rely on understanding the processes beyond the employed systems and using such knowledge to maximize the damage. This concept is commonly known as "semantic attack". Our paper discusses a specific type of semantic attack involving "sequences of events". Common network intrusion detection systems (NIDS) generally search for single, unusual or "not permitted" operations. In our case, rather than a malicious event, we show how a specific series of "permitted" operations can elude standard intrusion detection systems and still damage an infrastructure. Moreover, we present a possible approach to the development of a sequence-aware intrusion detection system (S-IDS). We propose a S-IDS reference architecture and we discuss all the steps through its implementations. Finally, we test the S-IDS on real ICS traffic samples captured from a water treatment and purification facility

Housing and the city. A spatial analysis of residential building activity and the socio-demographic background in a Mediterranean City, 1990-2017

Fluctuations in residential building activity are becoming progressively more intense over time and space in advanced economies and especially in Europe, fueling real estate market segmentation and making the performance of the construction industry increasingly unpredictable. If non-linear urbanization paths are the result of economic downturns consolidating progressively more volatile real estate markets, the present study investigates the impact of recent building cycles on long-term urban expansion in a Mediterranean city (Athens, Greece), using multiple clustering techniques run on a large set of building activity and socio-demographic indicators. Changes over time in building activity were evaluated considering 12 spatially-explicit indicators derived from the analysis of building permits released by Greek municipalities between 1990 and 2017. By referring to different analysis' scales (macro-scale: settlements, meso-scale: buildings, micro-scale: dwellings), indicators allow a comprehensive investigation of multiple dimensions and characteristics of construction markets at four-time intervals of 7 years each (1990-1996, 1997-2003, 2004-2010, 2011-2017). Spatio-temporal variability in building activity was further investigated considering 12 contextual indicators assessing the basic socio-demographic attributes of local municipalities. Cluster analysis allows identification of distinctive, local-scale responses of real estate markets to economic cycles (expansion-stagnation-recession) in both short- and long-term horizons and relate them to the dominant socio-demographic context. Density of new buildings, average floors per new building, density of buildings' additions and number of building permits per inhabitant were found to be the most sensitive indicators to economic downturns in the study area. Infrastructure-driven development, as a result of the 2004 Olympic Games, has produced relevant short-term alterations in residential construction markets, complicating urbanization trends at the local scale. Multi-scale indicators from building permit records provide a useful insight in the diachronic mechanisms of urban growth, with implications for regional planning and design of sustainable development practices

Population dynamics, agglomeration economies and municipal size. A long-term analysis

Under the hypothesis that modifications in municipal boundaries and creation (or suppression) of new administrative units reflect a progressive adjustment toward a more balanced distribution of population over space, the present study investigates the long-term relationship (1928-2012) between urban expansion, population dynamics and municipal area in a growing metropolitan region (Athens, Greece). In expanding regions, municipal size is a key variable outlining the amount and spatial concentration of services and infrastructures, resulting to be functionally related to population density, agglomeration factors, land availability to building and characteristic socioeconomic profiles of local communities. A statistical analysis of the relationship between population density and municipal area provides basic knowledge to policy and planning adjustments toward a more balanced spatial distribution of population and land among the local government units. Descriptive statistics, mapping, correlation analysis and linear regressions were used to assess the evolution of such relationship over a sufficiently long time period. The average municipal area in Athens decreased moderately over time, with a slight increase in spatial heterogeneity. Conversely, the average population density per municipality increased more rapidly, with a considerable reduction in spatial heterogeneity. The observed goodness-of-fit of the linear relationship between population density and municipal area increased significantly over time. The empirical results of our study indicate that municipal size has progressively adjusted to population density across metropolitan areas, determining a more balanced spatial distribution of the resident population, which was consolidated by the recent administrative reform of the local authorities in Greece (the so called \u2018Kallikratis\u2019 law). Such conditions represent a base for the informed analysis of the spatial structure of local administrative units and they contribute to the debate on the optimal size of municipalities and other administrative districts with relevant impact on both urban and metropolitan scales of governance

Urgent challenges in implementing live attenuated influenza vaccine.

Conflicting reports have emerged about the effectiveness of the live attenuated influenza vaccine. The live attenuated influenza vaccine appears to protect particularly poorly against currently circulating H1N1 viruses that are derived from the 2009 pandemic H1N1 viruses. During the 2015-16 influenza season, when pandemic H1N1 was the predominant virus, studies from the USA reported a complete lack of effectiveness of the live vaccine in children. This finding led to a crucial decision in the USA to recommend that the live vaccine not be used in 2016-17 and to switch to the inactivated influenza vaccine. Other countries, including the UK, Canada, and Finland, however, have continued to recommend the use of the live vaccine. This policy divergence and uncertainty has far reaching implications for the entire global community, given the importance of the production capabilities of the live attenuated influenza vaccine for pandemic preparedness. In this Personal View, we discuss possible explanations for the observed reduced effectiveness of the live attenuated influenza vaccine and highlight the underpinning scientific questions. Further research to understand the reasons for these observations is essential to enable informed public health policy and commercial decisions about vaccine production and development in coming years

Risk and protective factors for meningococcal disease in adolescents: matched cohort study

Objective: To examine biological and social risk factors for meningococcal disease in adolescents. Design: Prospective, population based, matched cohort study with controls matched for age and sex in 1:1 matching. Controls were sought from the general practitioner. Setting: Six contiguous regions of England, which represent some 65% of the country’s population. Participants: 15-19 year olds with meningococcal disease recruited at hospital admission in six regions (representing 65% of the population of England) from January 1999 to June 2000, and their matched controls. Methods: Blood samples and pernasal and throat swabs were taken from case patients at admission to hospital and from cases and matched controls at interview. Data on potential risk factors were gathered by confidential interview. Data were analysed by using univariate and multivariate conditional logistic regression. Results: 144 case control pairs were recruited (74 male (51%); median age 17.6). 114 cases (79%) were confirmed microbiologically. Significant independent risk factors for meningococcal disease were history of preceding illness (matched odds ratio 2.9, 95% confidence interval 1.4 to 5.9), intimate kissing with multiple partners (3.7, 1.7 to 8.1), being a university student (3.4, 1.2 to 10) and preterm birth (3.7, 1.0 to 13.5). Religious observance (0.09, 0.02 to 0.6) and meningococcal vaccination (0.12, 0.04 to 0.4) were associated with protection. Conclusions: Activities and events increasing risk for meningococcal disease in adolescence are different from in childhood. Students are at higher risk. Altering personal behaviours could moderate the risk. However, the development of further effective meningococcal vaccines remains a key public health priority