617 research outputs found
Regional differentiation of neuron morphology in human left and right hippocampus: Comparing normal to schizophrenia
Regional differentiation based on size, form, and orientation angle of the soma of individual neurons in human post-mortem hippocampus was determined through correlations between pairs of hippocampal subfields in each side separately. The neurons were previously measured on a computer. In the normal cases, a left-right asymmetrical pattern of regional differentiation based on soma size emerged, while for form and orientation angle, the patterns appeared symmetrical. In schizophrenia, regional soma size, form, and orientation variability were expressed largely symmetrically. Regional correlations based on neuronal density revealed an asymmetrical hemispheric pattern in the normal cases versus a nearly symmetrical pattern in schizophrenia. Taken together, the inter-regional correlations favor a hippocampal landscape that deviates in each side from connectivity based on the canonical trisynaptic hippocampal circuitry. It is proposed that during morphogenesis, rudimentary inter-regional networks are formed through specific interactions between regional neurons; these networks are present in the adult hippocampus and may be vulnerable in brain diseases
Appearance of symmetry, beauty, and health in human faces
Symmetry is an important concept in biology, being related to mate selection strategies, health, and survival of species. In human faces, the relevance of left-right symmetry to attractiveness and health is not well understood. We compared the appearance of facial attractiveness, health, and symmetry in three separate experiments. Participants inspected front views of faces on the computer screen and judged them on a 5-point scale according to their attractiveness in Experiment 1, health in Experiment 2, and symmetry in Experiment 3. We found that symmetry and attractiveness were not strongly related in faces of women or men while health and symmetry were related. There was a significant difference between attractiveness and symmetry judgments but not between health and symmetry judgments. Moreover, there was a significant difference between attractiveness and health. Facial symmetry may be critical for the appearance of health but it does not seem to be critical for the appearance of attractiveness, not surprisingly perhaps because human faces together with the human brain have been shaped by adaptive evolution to be naturally asymmetrical
Hemispheric effects of canonical views of category members with known typicality levels
Is there a preferred hemispheric canonical view of a visual concept? We investigated this question in a natural superordinate category membership decision task using a hemi-field paradigm. Participants had to decide whether or not an image of an object lateralized in the left (LVF) or right (RVF) visual half field is a member of a predesignated superordinate category. The objects represented high, medium, or low typicality levels, and each object had 6 different perspective views (front, front-right, front-left, side, back-left, and back-right). The latency responses revealed a significant interaction of Hemi Field X View X Typicality (there was no hemi-field difference in accuracy). The findings confirm the presence of asymmetry in stored concepts in long-term memory and suggest, in addition, a hemispheric canonical view of these concepts, a view strongly related to typicality level
The neural basis of the bilateral distribution advantage
Letters can be matched by their physical identity (i.e., a–a: same/A–a: different) or by their name (both a–a and A–a: same). The latter, more demanding task has in previous experiments led to an advantage of bilateral over within-hemifield matches, which was not observed in the former. We have investigated the neural basis of this bilateral distribution advantage (BDA) in letter name matching with event-related fMRI. Unilateral, compared to bilateral, name matching led to increased activation in the contralateral fusiform and lateral occipital gyri. This increase went along with an ipsilateral increase of activation in homologous areas. Such a hemispheric resource sharing was not observed for letter shape matching. This pattern of activation shows that letter name matching induces hemispheric resource sharing in visual areas, which occurs when task demands in the hemisphere of input reach a critical level. Activation in anterior cingulate complex and posterior cingulate/retrosplenial cortex showed a task × visual field interaction with lower activation for bilateral than unilateral name matches but higher activation for bilateral than unilateral shape matches, which fits the interhemispheric transfer demands in these tasks
Where does brain neural activation in aesthetic responses to visual art occur? Meta-analytic evidence from neuroimaging studies
Here we aimed at finding the neural correlates of the general aspect of visual aesthetic experience (VAE) and those more strictly correlated with the content of the artworks. We applied a general activation likelihood estimation (ALE) meta-analysis to 47 fMRI experiments described in 14 published studies. We also performed four separate ALE analyses in order to identify the neural substrates of reactions to specific categories of artworks, namely portraits, representation of real-world-visual-scenes, abstract paintings, and body sculptures. The general ALE revealed that VAE relies on a bilateral network of areas, and the individual ALE analyses revealed different maximal activation for the artworks' categories as function of their content. Specifically, different content-dependent areas of the ventral visual stream are involved in VAE, but a few additional brain areas are involved as well. Thus, aesthetic-related neural responses to art recruit widely distributed networks in both hemispheres including content-dependent brain areas of the ventral visual stream. Together, the results suggest that aesthetic responses are not independent of sensory, perceptual, and cognitive processe
Mountain-Shaped Coupler for Ultra Wideband Applications
This paper demonstrates a novel mountain-shaped design for a compact 3-dB coupler operating at ultra-wideband (UWB) frequencies from 3.1GHz to 10.6 GHz. The proposed design was accomplished using multilayer technology in which the structure is formed by three layers of conductors interleaved by a layer of substrate between each conductor layer. Simulation was carried out using CST Microwave Studio; the result was then compared with results from rectangular and star-shaped couplers that implemented the same technique. The results obtained show that the proposed new coupler has better performance compared to both rectangular and star-shaped coupler designs in terms of return loss, isolation, and phase difference. The coupler was fabricated and measured; the measurement results satisfactorily agree with the simulation results
The right-hemisphere and valence hypotheses: could they both be right (and sometimes left)?
The two halves of the brain are believed to play different roles in emotional processing, but the specific contribution of each hemisphere continues to be debated. The right-hemisphere hypothesis suggests that the right cerebrum is dominant for processing all emotions regardless of affective valence, whereas the valence specific hypothesis posits that the left hemisphere is specialized for processing positive affect while the right hemisphere is specialized for negative affect. Here, healthy participants viewed two split visual-field facial affect perception tasks during functional magnetic resonance imaging, one presenting chimeric happy faces (i.e. half happy/half neutral) and the other presenting identical sad chimera (i.e. half sad/half neutral), each masked immediately by a neutral face. Results suggest that the posterior right hemisphere is generically activated during non-conscious emotional face perception regardless of affective valence, although greater activation is produced by negative facial cues. The posterior left hemisphere was generally less activated by emotional faces, but also appeared to recruit bilateral anterior brain regions in a valence-specific manner. Findings suggest simultaneous operation of aspects of both hypotheses, suggesting that these two rival theories may not actually be in opposition, but may instead reflect different facets of a complex distributed emotion processing system
Compact wideband broadside-coupled microstrip-slot bandpass filter for communication applications
This paper proposes a compact size design of wideband bandpass filter (BPF). The broad-side coupling microstrip-slot technique is used to accomplish a good passband response with very low insertion loss across a wideband frequency range. The BPF that is designed using Rogers RO4003C substrate shows a good performance with the respective maximum reflection coefficient and insertion loss of -10 dB and 1.2 dB between 0.92 GHz and 5 GHz. This type of BPF filter is useful in any communication applications
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