GENDER COMPARISON STUDY OF ACHIEVEMENT MOTIVATION AMONG UNIVERSITY LEVEL BASKETBALL

The purpose of the current research is to explore the difference in the achievement Motivation level between male and female basketball players of Pakistan. The Achievement motivation is one of the types of motivation, which resolves around athlete’s persistence in the face of failure, willingness to approach the success, and experience of pride after the task accomplishment. People, who are achievement motivated, are very wise in their goal setting, they set moderate to difficult goals. The Sports Orientation questionnaire (SOQ) developed by Gill & Deeter (1988) was used to investigate the answer of “which gender has more achievement motivation for basketball at intervarsity level”. A total of 150 university level male & female students have voluntarily participated in the present research study. For statistical procedure, independent t-test at the set level of significance 0.05 was used to test the hypothesis. The Findings showed no consequential difference in the achievement motivation and mean score of male and female university level basketball players

Effect of short chain fatty acids on the expression of free fatty acid receptor 2 (Ffar2), Ffar3 and early-stage adipogenesis

Adipose tissue has a major influence on insulin sensitivity. Stimulation of free fatty acid receptor 2 (FFAR2) has been proposed to influence adipocyte differentiation. We hypothesised that exposing preadipocytes to short chain fatty acids would induce earlier expression of nuclear receptors that co-ordinate adipogenesis, triglyceride accumulation and leptin secretion. 3T3-L1 preadipocytes were differentiated in the presence of 1 μM acetate, 0.1–10 μM propionate or vehicle control. In experiment 1, expression of Ffar2 and nuclear receptor mRNA was measured by quantitative PCR over 48 h following onset of differentiation. In experiment 2, extracellular leptin concentration and intracellular triglyceride content were measured at days 0, 2, 4, 6, 8 and 10 following the onset of differentiation. Control cells exhibited similar temporal dynamics of gene expression, triglyceride accumulation and leptin secretion as reported previously. We were unable to detect expression of Ffar3 mRNA at any stage of differentiation. Consistent with a lack of Ffar2 expression in the first 24 h of differentiation, acetate and propionate had no significant effect on nuclear receptor expression. Furthermore, acetate or propionate treatment did not alter leptin concentration or triglyceride content. In conclusion, we observed no significant effect of propionate or acetate on adipogenesis in 3T3-L1 cells using validated quantitative techniques

Feasibility Study of a Facility to Produce Injection Molded Parts for Automotive Industry

[EN] This study aims at the preliminary assessment in designing a complete stand-alone industrial facility to produce injection molded parts for the automotive industry. A draft design solution to allow the company to evaluate the capital investment was performed giving an estimated solution in project profitability. Proposed successive design steps were developed. It includes the definition of input data and information, quantity determination, plat layout diagrams, machine selection, selection of material handling equipment, plant layout design including space requirements of production centers, aísles, support functions. Moreover, the outdoor facility masterplan design is also proposed. Finally, investment calculation via cash flow analysis is calculated.Yudianto, A.; Tan, H.; Qu, Z.; Xue, Q.; Naveen, A.; Mushtaq, M.; Gopi, K. (2020). Feasibility Study of a Facility to Produce Injection Molded Parts for Automotive Industry. International Journal of Production Management and Engineering. 8(1):45-57. https://doi.org/10.4995/ijpme.2020.12360455781Al-Aomar, R. (2006). Capacity-constrained production scheduling of multiple vehicle programs in automotive pilot plant. International Journal of Production Research, 44(13), 2573-2604. https://doi.org/10.1080/00207540500521212Cagliano, A. C., Chiabert, P. (2018). Plant and manufacturing system lecture notes. Politecnico di Torino, Italy.Chingua, S. Nyemba, W. R., Boora, K., Mbohwa, C. (2019). Feasibility study of the materials handling and development of a sustainable conveying system in plastics recycling and manufacture. Procedia Manufacturing, 33, 383-390. https://doi.org/10.1016/j.promfg.2019.04.047Derhami, S., Smith, J. S., Gue, K. R. (2019). Space-efficient layouts for block stacking warehouse. IISE Transaction, 51(9), 957-971. https://doi.org/10.1080/24725854.2018.1539280Eksangsri, T., Jaiwang, T. (2014). Feasibility study on reuse of washed water in electronic industry: case study for flexible printed circuit board manufacturing in Thailand. Procedia Environmental Sciences, 20, 206-214. https://doi.org/10.1016/j.proenv.2014.03.027Fu, M., Kaku, B. K. (1997). Minimizing work-in-process and material handling in the facilities layout problem. IIE Transactions, 29, 29-36. https://doi.org/10.1080/07408179708966309Halil, F. M., Nasir, N. M., Hassan, A. A., Shukur, A. S. (2016). Feasibility study and economic assessment in green building projects. Procedia-Social and Behavioral Sciences, 222, 56-64. https://doi.org/10.1016/j.sbspro.2016.05.176Hazaras, M. J., Swartz, C. L. E., Marlin, T. E. (2013). Industrial application of a continuous-time scheduling framework for process analysis and improvement. I&EC research Industrial & Engineering Chemistry Research, 53, 259-273. https://doi.org/10.1021/ie4006904Hwang, D. K., Cho, K., Moon, J. (2019). Feasibility study on energy audit and data driven analysis procedure for building energy efficiency: bench-marking in Korean hospital buildings. Journal Energy 12(15), 3006. https://doi.org/10.3390/en12153006Jung, S., Ng, D., Ovalle, C. D., Roman, R, V., Mannan, M. S. (2011). New approach to optimizing the facility sitting and layout for fire and explosion scenarios. I&EC research Industrial & Engineering Chemistry Research, 50, 3928-3937. https://doi.org/10.1021/ie101367gKingenberg, W., Boksma, J. D. (2010). A conceptual framework for outsourcing of material handling activities in automotive: differentiation and implementation. International Journal of Production Research, 48(16), 4877-4899. https://doi.org/10.1080/00207540903067177Kovàcs, G. (2019). Layout design for efficiency improvement and cost reduction. Bull. Pol. Ac.: Tech., 67(3), 547-555. https://doi.org/10.24425%2Fbpasts.2019.129653Ma, T., Yang, H., Lu. L., Qi, R. (2017). Feasibility study of developing a zero-carbon-emission green deck in Hong Kong. Energy Procedia 105, 1155-1159. https://doi.org/10.1016/j.egypro.2017.03.487Morgan, B., Hejdenberg, J., Krapels, S. H., Amstrong, D. (2018). DO feasibility studies contribute to, or avoid, waste in research? PLos ONE 13(4), e0195951. https://doi.org/10.1371/journal.pone.0195951Pòvoa, A. P. B., (2002). Optimal design and layout of industrial facilities: a simultaneous approach. Ind. Eng. Chem. Res, 41, 3601-3609. https://doi.org/10.1021/ie010660sSchaller, J. (2008). Incorporating cellular manufacturing into supply chain design. International Journal of Production Research, 46(17), 4925-4945. https://doi.org/10.1080/00207540701348761Stephens, M. P., Meyers, F. E., (2013). Manufacturing facilities design and material handling - fifth edition. Purdue University Press, West Lafayette, Indiana.Sun, L., Luan, F., Pian, J. (2015). An effective approach for scheduling of refining process with uncertain iterations in steel-making and continuous casting process. IFAC-PapersOnLine, 48(3), 1966-1972. https://doi.org/10.1016/j.ifacol.2015.06.376Yang, Z., Djurdjanovic, D., Ni, J. (2007). Maintenance scheduling for a manufacturing system of machines with adjustable throughput. IIE Transactions, 39, 1111-1125. https://doi.org/10.1080/0740817070131533

Synthesis of New Heterocyclic Compound Used as Corrosion Inhibitor for Crude Oil Pipelines

This study comprises synthesis of new heterocyclic compound  through  one of the most powerful  methods in organic synthesis  and which comprises formation of several bonds in a single transformation and all interaction materials have been combined in one pot since beginning of interaction. This compound contains  on nitrogen, oxygen and sulfur atoms and is 3,5,12-trithia-1,7,14-triaza-tricycle [5.3.3.27,10] tetradeca-6(14),9-dien-8-one, and its structure has been  determined  by using several techniques such as, Nuclear magnetic resonance spectrophotometer for proton 1H-NMR and carbon13C- NMR, Infra-red spectroscopy FT-IR, and Mass spectroscopy MS. The last part  is the study and application of  compound as a inhibitor for  corrosion crude oil pipelines (N-80 type)  in saline water  as a corrosive medium and has been evaluated by using weight loss method, as well as has been evaluated through electrochemical techniques such as potentiodynamic polarization, electrochemical impedance spectroscopy EIS, and scanning electron microscopy- energy dispersive X-ray spectroscopy SEM/EDX. The effect of time and concentration on the corrosion rate  have been  studied and was observed that efficiency of inhibition  increased with increase  inhibitor concentration to attain a maximum values of 90.12%, 90.62%, 79.70%,  90.05%  to weight loss method, polarization technique, impedance technique and  energy dispersive X-ray technique respectively. Finally the prepared inhibitor was compared with some of disincentives commercial used in the south oil company such as, AS-101, WFT-9368, COIL GARD, HQI-85M and AL-600

Functional quality of optimized peach‐based beverage developed by application of ultrasonic processing

The influence of thermal treatment (at 90°C for 10 min) and sonication (at 20 kHz and 130 W for 30, 60, and 90 min on room temperature) on the physicochemical properties, bioactive compounds, antioxidant activity, and organic acids of fresh formulated functional peach beverage was investigated. The results indicated that conventional pasteurization and sonication treatment did not show any significant changes in pH value and Brix amount of juice, and however, a rise in cloud value was observed under all processing conditions. The thermal treatment caused the decrement in total phenolic content (TPC), total flavonoid content (TFC), antioxidant activity (assessed by diphenyl dipicryl hydrazyl (DPPH), ferric ion reducing antioxidant power (FRAP) and 2,2'‐azino‐bis(3‐ethylbenzothiazoline‐6‐sulfonic acid) (ABTS)), and organic acids of juice, whereas sonication treatment for 90 min increased maximum the activity of bioactive compounds (TPC: 600.61 µg/100 ml; TFC: 177 µg CE/100 ml), antioxidants (DPPH: 51.87%; FRAP: 506.13 µmol Trolox/L; ABTS: 1,507.375 µmol Trolox/L), and organic acids (malic acid: 998; citric acid: 128; oxalic acid: 145; shikimic acid: 63 µg/100 ml) as compared to other treatment conditions and control. Multivariate data analysis was done by principal component analysis as it identifies patterns in data by comparing data sets which is further expressed based on their similarities and discriminations, respectively

Synthesis of 3-[4-(2-furoyl)-1-piperazinyl]-N- (substituted)propanamides as promising antibacterial agents with mild cytotoxicity

Purpose: To evaluate the antibacterial activity and cytotoxicity of a series of molecules with amalgamation of furoyl, piperazine and amide moieties.Methods: New derivatives, namely 3-[4-(2-furoyl)-1-piperazinyl]-N-(substituted) propanamides, were synthesized and evaluated for their antibacterial activity and toxicity to mammalian cells. The synthesis was initiated by treating different aryl/aralkyl amines (1a-u) with 3-bromopropionyl chloride (2) to obtain the solid electrophiles 3a-u, which were collected by filtration. Thereafter, the different N-aryl/aralkyl-3- bromopropionamides (3a-u) and 2-furoyl-1-piperazine (4) at equimolar ratios were allowed to react in acetonitrile and in the presence of a base, K2CO3, to form the target compounds, 5a-u. Structural elucidation was carried out using EI-MS (electron impact mass spectrometry), IR (infrared) and 1H-NMR (proton nuclear magnetic resonance). The antibacterial activity of the synthesized compounds was evaluated against various bacterial strains. Furthermore, hemolysis was determined to assess cytotoxicity using bovine red blood cells.Results: Molecules 5g, 5a, 5p, 5g and 5i were found to be potent agents against S. aureus, S. typhi, P. aeruginosa, E. coli and B. subtilis with respective minimum inhibitory concentration (MIC) values of 8.34 ± 0.55, 8.37 ± 0.12, 8.65 ± 0.57, 8.97 ± 0.12 and 9.24 ± 0.50 μM, compared to 7.80 ± 0.19, 7.45 ± 0.58, 7.14 ± 0.58, 7.16 ± 0.58 and 7.29 ± 0.90 μM for the reference standard, ciprofloxacin. The most active compounds, 5a, 5g, 5i and 5p, showed a hemolysis of 15.48, 8.03, 5.52 and 4.35 %, respectively.Conclusion: The synthesized compounds exhibit good antibacterial activity. The hemolysis data indicate that these compounds have a low toxicity level. However, in vivo studies are required to ascertain their potentials as new drug candidates.Keywords: 4-(2-Furoyl)-1-piperazine, 1H-NMR, EI-MS, Antimicrobial activity, Hemolytic activit

Haemoglobin Video Imaging provides novel in vivo high-resolution imaging and quantification of human aqueous outflow in glaucoma patients

Purpose Non-invasive, detailed measurement of the dynamics of human aqueous outflow is difficult to achieve with currently available clinical tools. Here we used haemoglobin video imaging (HVI) to develop a technique to image and quantify human aqueous outflow non-invasively and in real time. Design A prospective observational study to describe characteristics of aqueous veins and a pilot prospective interventional feasibility study to develop quantification parameters. Subjects Participants and/or Controls: Patients were recruited from the Addenbrookes Hospital Glaucoma clinic. The observational study included 30 eyes and the pilot interventional feasibility study was performed on 8 eyes undergoing selective laser trabeculoplasty (SLT). Our SLT protocol also included the installation of pilocarpine and apraclonidine eye drops. Methods, Intervention, or Testing Participants underwent HVI alongside their usual clinic visit. Main Outcome Measures The change in cross sectional area (CSA) of the aqueous column (AQC) within episcleral veins was correlated with IOP reduction and change in visual field mean deviation before and after intervention. Fluctuations in contrast and pixel intensity of red blood cells in an aqueous vein were calculated to compare the flow rate before and after intervention using autocorrelation analysis. Results HVI enables the direct observation of aqueous flow into the vascular system. Aqueous is seen to centralise within a laminar venous column. Flow is pulsatile, and fluctuations of flow through globe pressure or compression of the aqueous vein are observed. There was a significant increase in the AQC following the administration of our SLT protocol (n=13; p<0.05). This correlated with the degree of IOP reduction (n=13; Pearson’s correlation coefficient 0.7; p=0.007) and the improvement in mean deviation (MD) observed post intervention (n=8; Pearson’s correlation coefficient 0.75; p=0.03). Autocorrelation analysis demonstrated a faster rate of decay in an aqueous vein following intervention indicating an increase in flow rate. Conclusions HVI can be incorporated into a routine clinic slit lamp examination to allow a detailed assessment and quantification of aqueous outflow in real time. It has the potential to be used to help target therapeutic interventions to improve aqueous outflow and further advance our understanding of aqueous outflow dysregulation in the pathogenesis of glaucoma.This work was supported by grants from Addenbrooke’s Charitable Trust, the HB Allen Charitable Trust, the Cambridge Eye Trust, the Jukes Glaucoma Research Fund and a core support grant from the Wellcome Trust and MRC to the Wellcome Trust – Medical Research Council Cambridge Stem Cell Institute

Hemoglobin Video Imaging Provides Novel In Vivo High-Resolution Imaging and Quantification of Human Aqueous Outflow in Patients with Glaucoma.

Purpose:Noninvasive, detailed measurement of the dynamics of human aqueous outflow is difficult to achieve with currently available clinical tools. We used hemoglobin video imaging (HVI) to develop a technique to image and quantify human aqueous outflow noninvasively and in real time. Design:A prospective observational study to describe characteristics of aqueous veins and a pilot prospective interventional feasibility study to develop quantification parameters. Participants:Patients were recruited from the Cambridge University Hospitals NHS Foundation Trust Glaucoma clinic. The observational study included 30 eyes, and the pilot interventional feasibility study was performed on 8 eyes undergoing selective laser trabeculoplasty (SLT). Our SLT protocol also included the installation of pilocarpine and apraclonidine eye drops. Methods:Participants underwent HVI alongside their usual clinic visit. Main Outcome Measures:The change in cross-sectional area (CSA) of the aqueous column within episcleral veins was correlated with intraocular pressure (IOP) reduction and change in visual field mean deviation (MD) before and after intervention. Fluctuations in contrast and pixel intensity of red blood cells in an aqueous vein were calculated to compare the flow rate before and after intervention using autocorrelation analysis. Results:Hemoglobin video imaging enables the direct observation of aqueous flow into the vascular system. Aqueous is seen to centralize within a laminar venous column. Flow is pulsatile, and fluctuations of flow through globe pressure or compression of the aqueous vein are observed. There was a significant increase in the aqueous column after the administration of our SLT protocol (n = 13; P < 0.05). This correlated with the degree of IOP reduction (n = 13; Pearson's correlation coefficient 0.7; P = 0.007) and the improvement in MD observed postintervention (n = 8; Pearson's correlation coefficient 0.75; P = 0.03). Autocorrelation analysis demonstrated a faster rate of decay in an aqueous vein after intervention, indicating an increase in flow rate. Conclusions:Hemoglobin video imaging can be incorporated into a routine clinic slit-lamp examination to allow a detailed assessment and quantification of aqueous outflow in real time. It has the potential to be used to help target therapeutic interventions to improve aqueous outflow and further advance our understanding of aqueous outflow dysregulation in the pathogenesis of glaucoma

Magnetoelectric Effect in Hydrogen Harvesting: Magnetic Field as a Trigger of Catalytic Reactions (Adv. Mater. 19/2022)

Magnetic fields have been regarded as an additional stimulus for electro- and photocatalytic reactions, but not as a direct trigger for catalytic processes. Multiferroic/magnetoelectric materials, whose electrical polarization and surface charges can be magnetically altered, are especially suitable for triggering and control of catalytic reactions solely with magnetic fields. Here, we demonstrate that magnetic fields can be employed as an independent input energy source for hydrogen harvesting by means of the magnetoelectric effect. Composite multiferroic CoFe2O4-BiFeO3 core-shell nanoparticles act as catalysts for the hydrogen evolution reaction (HER) that is triggered when an alternating magnetic field is applied to an aqueous dispersion of the magnetoelectric nanocatalysts. Based on density functional calculations, we propose that the hydrogen evolution is driven by changes in the ferroelectric polarization direction of BiFeO3 caused by the magnetoelectric coupling. We believe our findings will open new avenues towards magnetically induced renewable energy harvesting