107 research outputs found
Les groupements d'intĂ©rĂȘt Ă©conomique
Collaboration between different business enterprises has become a must in our days of financial, technical and commercial complexity. It is highly encouraged by governments and businessmen. The traditional legal techniques known and frequently used in Canada appear however to be inadequate in some cases. The French legislator has innovated in the field by creating, in 1967, the legal framework of the Groupement d'intĂ©rĂȘt Ă©conomique (G.I.E.) The G.I.E. is an institution that has the separate legal entity of the corporation while maintaining the joint, several and illimited liability of the partners. The G.I.E. is all the way neutral. It is not aimed to generate direct profits for itself or the partners but allows the involved partners to have a better overall performance. Since 1967, over 9000 G.I.E. have been created in France to cover fields as different as the Airbus joint venture, communal maintenance services, research publicity or marketing department, buying or export offices, etc. This article, written by a leading academic, discusses the different legal aspect of the G.I.E. and explains the pros and cons of the institution
Analysis of the copy number profiles of several tumor samples from the same patient reveals the successive steps in tumorigenesis
We present a computational method, TuMult, for reconstructing the sequence of copy number changes driving carcinogenesis, based on the analysis of several tumor samples from the same patient. We demonstrate the reliability of the method with simulated data, and describe applications to three different cancers, showing that TuMult is a valuable tool for the establishment of clonal relationships between tumor samples and the identification of chromosome aberrations occurring at crucial steps in cancer progression
The Achromatic Interfero Coronagraph
We report on the Achromatic Interfero Coronagraph, a focal imaging device which aims at rejecting the energy contribution of a point-like source set on-axis, so as to make detectable its angularly-close environment (applicable to stellar environment: circumstellar matter, faint companions, planetary systems, but also conceivably to Active Galatic Nucleii and multiple asteroids). With AIC, starlight rejection is based on destructive interference, which allows exploration of the star's neighbouring at angular resolution better than the diffraction limit of the hosting telescope. Thanks to the focus crossing property of light, rejection is achromatic thus yielding a large spectral bandwidth of work. Descriptions and comments are given regarding the principle, the device itself, the constraints and limitations, and the theoretical performance. Results are presented which demonstrate the close-sensing capability and which show images of a companion obtained in laboratory and 'on the sky' as well. A short pictorial description of alternative AIC concepts, CIAXE and Open-Air CIAXE, currently under study, is given
L officine dans le contexte social et Ă©conomique actuel (la voie des groupements )
Les dĂ©penses de santĂ© atteignent des niveaux trĂšs Ă©levĂ©s dans les pays dĂ©veloppĂ©s. La France enregistre des dĂ©ficits consĂ©quents que les gouvernements tentent d endiguer. Les professionnels de santĂ© participent Ă la maĂźtrise mĂ©dicalisĂ©e des dĂ©penses notamment les pharmaciens, diminuant par la mĂȘme occasion la rentabilitĂ© de leurs officines. Pour les pharmaciens endettĂ©s et pour les petites officines les rĂ©percussions peuvent ĂȘtre fatales. Au-delĂ de cet aspect Ă©conomique le pharmacien se voit attribuer de nouvelles missions. Les pharmaciens conscients de l avĂšnement d une conjoncture Ă©conomique de moins en moins favorable, et du fait de l Ă©volution de leur mĂ©tier sont de plus en plus nombreux Ă adhĂ©rer Ă des groupements. En se ralliant Ă ces groupements ils espĂšrent que ceux ci vont les accompagner favorablement dans l Ă©volution de leur profession.NANTES-BU MĂ©decine pharmacie (441092101) / SudocSudocFranceF
- âŠ