12 research outputs found

    ジッセンテキ タイケンテキ カツドウ オ チュウカク ト スル カテイカ キョウイク ジッセン ジレイ ノ コウサツ カテイ ノ シゴト ヤ カゾク トノ フレアイ ハッコウ センショク ノ ジュギョウ

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    The purpose of this study is to analyze core practical activities on housework and communication with family, fermentation, dyeing with indigo in Home Economics education. The results were as follows. 1, On housework and communication with family, practical activities by nonverbal communication are necessary. 2, On fermentation, it is necessary to instruct with people at community and to cooperate in food life. 3, On dyeing, teaching materials on the deposited indigo are necessary

    スナ ノ シロ ニオケル カンソウセイ

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    A new species of Eimeria Schneider, 1875 from a cracid bird, Mitu tuberosum Spix, held in captivity is described from Brazil. Oöcysts of Eimeria abmitu n. sp. are ovoid, with a smooth, colourless, bilayered wall, measure 24.2 × 15.5 μm and have a length/width ratio of 1.56. The sporulated oöcysts contain two to five polar granules and four ellipsoidal sporocysts measuring 13.6 × 6.4 μm, each with a small crescent-shaped Stieda body, a sub-Stieda body, a loosely granular sporocyst residuum and two comma-shaped sporozoites each with a spherical refractile body.7869-7

    Filamin acts as a key regulator in epithelial defence against transformed cells

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    Recent studies have shown that certain types of transformed cells are extruded from an epithelial monolayer. However, it is not known whether and how neighbouring normal cells play an active role in this process. In this study, we demonstrate that filamin A and vimentin accumulate in normal cells specifically at the interface with Src- or RasV12-transformed cells. Knockdown of filamin A or vimentin in normal cells profoundly suppresses apical extrusion of the neighbouring transformed cells. In addition, we show in zebrafish embryos that filamin plays a positive role in the elimination of the transformed cells. Furthermore, the Rho/Rho kinase pathway regulates filamin accumulation and filamin acts upstream of vimentin in the apical extrusion. This is the first report demonstrating that normal epithelial cells recognize and actively eliminate neighbouring transformed cells and that filamin is a key mediator in the interaction between normal and transformed epithelial cells
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