775 research outputs found

    A novel self-routing scheme for all-optical packet switched networks with arbitrary topology

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    Due to limited available photonic devices, optical networks in the near future will likely employ routing schemes that do not require sophisticated processing of optical packets. In this paper, we propose a novel self-routing scheme for all-optical packet networks that can be applied to networks with arbitrary topology. The proposed routing scheme requires only single bit processing and can be implemented with existing technologies.published_or_final_versio

    A novel self-routing address scheme for all-optical packet-switched networks with arbitrary topologies

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    Pure all-optical packet-switched networks in which both header processing and packet routing are carried out in the optical domain overcome the bandwidth bottlenecks of optoelectronic conversions and therefore are expected to meet the needs of next generation high speed networks. Due to the limited capabilities of available optical logic devices, realizations of pure all-optical packet-switched networks in the near future will likely employ routing schemes that minimize the complexity of routing control. In this paper, we propose a novel self-routing scheme that identifies the output ports of the nodes in a network instead of the nodes themselves. The proposed address scheme requires single bit processing only and is applicable to small to medium size pure all-optical packet-switched networks with arbitrary topologies. Unlike traditional self-routing schemes, multiple paths between two nodes can be defined. Hierarchical address structure can be used in the proposed routing scheme to shorten the address.published_or_final_versio

    Deflection routing in slotted self-routing networks with arbitrary topology

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    A deflection routing algorithm that can be applied to a novel self-routing address scheme for networks with arbitrary topology is proposed. The proposed deflection routing algorithm can be implemented all-optically using bitwise optical logic gates. Besides the primary output link selection, alternate output link choices by a packet at each node in case of deflection are also encoded in the address header. Priority classes can also be defined in the proposed address scheme. The performance of the deflection routing algorithm is studied using the AT&T North America OC-48 optical fiber network topology.published_or_final_versio

    Multicasting in deflection-routed all-optical packet-switched networks

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    Two multicast protocols are proposed for deflection-routed all-optical packet-switched networks. One scheme sends a deflected multicast packet back to the root node while the other sends it back to the deflection point Both schemes can be implemented using demonstrated optical signal processing technology. The performance of the two proposed multicast schemes are compared using Manhattan Street Networks. We found that the back-to-the-root-node scheme performed better than the back-to-the-deflection-node scheme. A hybrid approach can further improve the system performance.published_or_final_versio

    Using 2x2 switching modules to build large 2-D MEMS optical switches

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    MEMS optical switch technology is one of the key technologies in wavelength division multiplexing (WDM) optical networks. Although the 2-D MEMS optical switch technology is mature, the commonly used crossbar architecture is not amenable to building large switches. In this paper, we propose a design of 2x2 switching modules, and use it to build large 2-D MEMS optical switches with architectures such as Spanke-Benes and Benes networks.published_or_final_versio

    New progress in LURR-integrating with the dimensional method

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    The evolution laws of LURR (Loading-Unloading Response Ratio) before strong earthquakes, especially the peak point of LURR, are described in this paper. The results of four methods (experimental, numerical simulation, seismic data analysis and with damage mechanics analysis) lead to a consistent conclusion-the evolution laws of LURR before strong earthquakes are that, at the early stage of the seismic cycle, LURR will fluctuate around 1 and in the late stage, it rises swiftly and to its peak point. At some time after this peak point, a catastrophic event or events occur. These do not occur at the peak point, but lag behind. The lag time which is denoted by T (2) depends on the magnitude M of the upcoming earthquake among other factors. In order to consider the influence of geophysical parameters in a specific region such as E (a) and J ((t)), where is the shear strain rate of tectonic loading in situ, E (a) is the sum of radiated energy of all earthquake occurring in a specific region measured during a long time duration (110 years in this paper) divided by the area of the region and the time duration, and J ((t)) is a parameter denoting the LURR anomaly area weighted with Y (the value of LURR) and represents the expanse and degree of the seismogenic zone. The dimensional analysis method has been used to reveal the relation between M, T (2) and other parameters in situ for more reliable earthquake prediction

    Tumor-suppressor activity of RRIG1 in breast cancer

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    <p>Abstract</p> <p>Background</p> <p>Retinoid receptor-induced gene-1 (RRIG1) is a novel gene that has been lost in several types of human cancers. The aim of this study was to determine whether RRIG1 plays a role in breast cancer, such as in the suppression of breast cancer cell growth and invasion.</p> <p>Methods</p> <p>Immunohistochemistry was used to detect RRIG1 expression in breast tissue specimens. Gene transfection was used to restore or knock down RRIG1 expression in breast cancer cell lines for analysis of cell viability, colony formation, and migration/invasion potential. Reverse-transcription polymerase chain reaction and western blot assays were used to detect the changes in gene expression. The RhoA activation assay was used to assess RRIG1-induced inhibition of RhoA activity.</p> <p>Results</p> <p>The immunohistochemical data showed that <it>RRIG1 </it>expression was reduced in breast cancer tissues compared with normal and atypical hyperplastic breast tissues. <it>RRIG1 </it>expression was inversely correlated with lymph node metastasis of breast cancer but was not associated with the status of hormone receptors, such as estrogen receptor, progesterone receptor, or HER2. Furthermore, restoration of <it>RRIG1 </it>expression inhibited proliferation, colony formation, migration, and invasion of breast cancer cells. Expression of RRIG1 also reduced phosphorylated Erk1/2 and Akt levels; c-Jun, MMP9, and Akt expressions; and RhoA activity. In contrast, knockdown of RRIG1 expression promoted breast cancer cell proliferation, colony formation, migration, and invasion potential.</p> <p>Conclusion</p> <p>The data from the current study indicated that <it>RRIG1 </it>expression was reduced or lost in breast cancer and that restoration of RRIG1 expression suppressed breast cancer cell growth and invasion capacity. Future studies will determine the underlying molecular mechanisms and define RRIG1 as a tumor-suppressor gene in breast cancer.</p

    Shape-Controlled Synthesis of ZnS Nanostructures: A Simple and Rapid Method for One-Dimensional Materials by Plasma

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    In this paper, ZnS one-dimensional (1D) nanostructures including tetrapods, nanorods, nanobelts, and nanoslices were selectively synthesized by using RF thermal plasma in a wall-free way. The feeding rate and the cooling flow rate were the critical experimental parameters for defining the morphology of the final products. The detailed structures of synthesized ZnS nanostructures were studied through transmission electron microscope, X-ray diffraction, and high-resolution transmission electron microscope. A collision-controlled growth mechanism was proposed to explain the growth process that occurred exclusively in the gas current by a flowing way, and the whole process was completed in several seconds. In conclusion, the present synthetic route provides a facile way to synthesize ZnS and other hexagonal-structured 1D nanostructures in a rapid and scalable way

    Observation of CR Anisotropy with ARGO-YBJ

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    The measurement of the anisotropies of cosmic ray arrival direction provides important informations on the propagation mechanisms and on the identification of their sources. In this paper we report the observation of anisotropy regions at different angular scales. In particular, the observation of a possible anisotropy on scales between \sim 10 ^{\circ} and \sim 30 ^{\circ} suggests the presence of unknown features of the magnetic fields the charged cosmic rays propagate through, as well as potential contributions of nearby sources to the total flux of cosmic rays. Evidence of new weaker few-degree excesses throughout the sky region 195195^{\circ}\leq R.A. 315\leq 315^{\circ} is reported for the first time.Comment: Talk given at 12th TAUP Conference 2011, 5-9 September 2011, Munich, German

    Counter-current chromatography for the separation of terpenoids: A comprehensive review with respect to the solvent systems employed

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    Copyright @ 2014 The Authors.This article is distributed under the terms of the Creative Commons Attribution License which permits any use, distribution, and reproduction in any medium, provided the original author(s) and the source are credited.Natural products extracts are commonly highly complex mixtures of active compounds and consequently their purification becomes a particularly challenging task. The development of a purification protocol to extract a single active component from the many hundreds that are often present in the mixture is something that can take months or even years to achieve, thus it is important for the natural product chemist to have, at their disposal, a broad range of diverse purification techniques. Counter-current chromatography (CCC) is one such separation technique utilising two immiscible phases, one as the stationary phase (retained in a spinning coil by centrifugal forces) and the second as the mobile phase. The method benefits from a number of advantages when compared with the more traditional liquid-solid separation methods, such as no irreversible adsorption, total recovery of the injected sample, minimal tailing of peaks, low risk of sample denaturation, the ability to accept particulates, and a low solvent consumption. The selection of an appropriate two-phase solvent system is critical to the running of CCC since this is both the mobile and the stationary phase of the system. However, this is also by far the most time consuming aspect of the technique and the one that most inhibits its general take-up. In recent years, numerous natural product purifications have been published using CCC from almost every country across the globe. Many of these papers are devoted to terpenoids-one of the most diverse groups. Naturally occurring terpenoids provide opportunities to discover new drugs but many of them are available at very low levels in nature and a huge number of them still remain unexplored. The collective knowledge on performing successful CCC separations of terpenoids has been gathered and reviewed by the authors, in order to create a comprehensive document that will be of great assistance in performing future purifications. © 2014 The Author(s)
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