21 research outputs found

    Modeling rare pediatric neurogenetic disorders with IPSCs

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    The <em>Drosophila</em> gonads: models for stem cell proliferation, self-renewal, and differentiation

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    Model-based Cross-correlation Search for Gravitational Waves from the Low-mass X-Ray Binary Scorpius X-1 in LIGO O3 Data

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    We present the results of a model-based search for continuous gravitational waves from the low-mass X-ray binary Scorpius X-1 using LIGO detector data from the third observing run of Advanced LIGO and Advanced Virgo. This is a semicoherent search that uses details of the signal model to coherently combine data separated by less than a specified coherence time, which can be adjusted to balance sensitivity with computing cost. The search covered a range of gravitational-wave frequencies from 25 to 1600 Hz, as well as ranges in orbital speed, frequency, and phase determined from observational constraints. No significant detection candidates were found, and upper limits were set as a function of frequency. The most stringent limits, between 100 and 200 Hz, correspond to an amplitude h0 of about 10−25 when marginalized isotropically over the unknown inclination angle of the neutron star's rotation axis, or less than 4 × 10−26 assuming the optimal orientation. The sensitivity of this search is now probing amplitudes predicted by models of torque balance equilibrium. For the usual conservative model assuming accretion at the surface of the neutron star, our isotropically marginalized upper limits are close to the predicted amplitude from about 70 to 100 Hz; the limits assuming that the neutron star spin is aligned with the most likely orbital angular momentum are below the conservative torque balance predictions from 40 to 200 Hz. Assuming a broader range of accretion models, our direct limits on gravitational-wave amplitude delve into the relevant parameter space over a wide range of frequencies, to 500 Hz or more

    Search for subsolar-mass black hole binaries in the second part of Advanced LIGO’s and Advanced Virgo’s third observing run

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    Searches for gravitational waves from known pulsars at two harmonics in the second and third LIGO-Virgo observing runs

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    We present a targeted search for continuous gravitational waves (GWs) from 236 pulsars using data from the third observing run of LIGO and Virgo (O3) combined with data from the second observing run (O2). Searches were for emission from the l = m = 2 mass quadrupole mode with a frequency at only twice the pulsar rotation frequency (single harmonic) and the l = 2, m = 1, 2 modes with a frequency of both once and twice the rotation frequency (dual harmonic). No evidence of GWs was found, so we present 95% credible upper limits on the strain amplitudes h0 for the single-harmonic search along with limits on the pulsars' mass quadrupole moments Q22 and ellipticities ε. Of the pulsars studied, 23 have strain amplitudes that are lower than the limits calculated from their electromagnetically measured spin-down rates. These pulsars include the millisecond pulsars J0437−4715 and J0711−6830, which have spin-down ratios of 0.87 and 0.57, respectively. For nine pulsars, their spin-down limits have been surpassed for the first time. For the Crab and Vela pulsars, our limits are factors of ∼100 and ∼20 more constraining than their spin-down limits, respectively. For the dual-harmonic searches, new limits are placed on the strain amplitudes C21 and C22. For 23 pulsars, we also present limits on the emission amplitude assuming dipole radiation as predicted by Brans-Dicke theory

    Search for Subsolar-Mass Binaries in the First Half of Advanced LIGO’s and Advanced Virgo’s Third Observing Run

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    International audienceWe report on a search for compact binary coalescences where at least one binary component has a mass between 0.2  M⊙ and 1.0  M⊙ in Advanced LIGO and Advanced Virgo data collected between 1 April 2019 1500 UTC and 1 October 2019 1500 UTC. We extend our previous analyses in two main ways: we include data from the Virgo detector and we allow for more unequal mass systems, with mass ratio q≥0.1. We do not report any gravitational-wave candidates. The most significant trigger has a false alarm rate of 0.14  yr-1. This implies an upper limit on the merger rate of subsolar binaries in the range [220−24200]  Gpc-3 yr-1, depending on the chirp mass of the binary. We use this upper limit to derive astrophysical constraints on two phenomenological models that could produce subsolar-mass compact objects. One is an isotropic distribution of equal-mass primordial black holes. Using this model, we find that the fraction of dark matter in primordial black holes in the mass range 0.2  M⊙&lt;mPBH&lt;1.0  M⊙ is fPBH≡ΩPBH/ΩDM≲6%. This improves existing constraints on primordial black hole abundance by a factor of ∼3. The other is a dissipative dark matter model, in which fermionic dark matter can collapse and form black holes. The upper limit on the fraction of dark matter black holes depends on the minimum mass of the black holes that can be formed: the most constraining result is obtained at Mmin=1  M⊙, where fDBH≡ΩDBH/ΩDM≲0.003%. These are the first constraints placed on dissipative dark models by subsolar-mass analyses

    Search for continuous gravitational wave emission from the Milky Way center in O3 LIGO-Virgo data

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    International audienceWe present a directed search for continuous gravitational wave (CW) signals emitted by spinningneutron stars located in the inner parsecs of the Galactic Center (GC). Compelling evidence for the presenceof a numerous population of neutron stars has been reported in the literature, turning this region into a veryinteresting place to look for CWs. In this search, data from the full O3 LIGO-Virgo run in the detectorfrequency band [10, 2000] Hz have been used. No significant detection was found and 95% confidencelevel upper limits on the signal strain amplitude were computed, over the full search band, with the deepestlimit of about 7.6×10267.6 \times 10^{-26} at ≃142 Hz. These results are significantly more constraining than those reportedin previous searches. We use these limits to put constraints on the fiducial neutron star ellipticity andr-mode amplitude. These limits can be also translated into constraints in the black hole mass–boson massplane for a hypothetical population of boson clouds around spinning black holes located in the GC
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