The age specificity of nutrition of medical students

It is necessary that the question of nutrition covers a prevail part of the human’s health. It holds a special place for people, including students, because the average age of student (18-22 years old) refers to period of final period of body growth. Aim and tasks. It was study and analysis of relation between the factual nutrition of students and their age

The age specificity of nutrition of medical students

It is necessary that the question of nutrition covers a prevail part of the human’s health. It holds a special place for people, including students, because the average age of student (18-22 years old) refers to period of final period of body growth. Aim and tasks. It was study and analysis of relation between the factual nutrition of students and their age

Study of effect of damage accumulation on stress distribution parameters in mesovolume of biocomposite and its performance characteristics

Abstract—A numerical study of mechanical properties of zirconium ceramic–cortical bone tissue biocomposite has been fulfilled using a multiple-scale approach. Evolution of mesoscopic stress distribution in the components of biocomposite during its deformation has been studied with the assumption of damage accumulation until the macrostrength criterion is fulfilled. It has been shown that the parameters of the laws of distribution change with damage accumulation

STRUCTURE FORMATION PROCESS OF HYDRATED PORTLAND CEMENT COMPOSITIONS: NANOSCALE LEVEL CONTROL

Durability of cement-like construction materials, as well as durability of cement stone, depends on their humidity resistance, frost resistance, corrosion resistance. All of these properties depend not only on the composition of the original clinker, but also on structural organization at micro-and nanoscale level of hydrated portland cement compositions. In this research the authors used the method of small-angle neutron scattering to define structural parameters of hydrated portland cement compositions on nanoscale level, distribution of calcium hydrate silicate nanoparticles in size, medium nanoparticles radius, fractal dimension. It is shown, that introduction of modifying nanoadditives into portland cement compositions affects structural parameters of a cement stone. The following nanoadditives were used: of artificial (alpha aluminium oxide, gamma aluminum oxide) and of anthropogenic (carbonate and alumo-alkaline sludges) origin, as well as integrated nanoadditives containing surfactants. The change in structural parameters of portland cement compositions with nanoadditives in the process of hydration is investigated. It is shown that use of nanoadditives allows to control the process of forming the structure of hydrated portland cement composition on the nanoscale level, directly affect the values of structural parameters and, as a result, modify properties of cement stone

Beyond Moore's technologies: operation principles of a superconductor alternative

The predictions of Moore's law are considered by experts to be valid until 2020 giving rise to "post-Moore's" technologies afterwards. Energy efficiency is one of the major challenges in high-performance computing that should be answered. Superconductor digital technology is a promising post-Moore's alternative for the development of supercomputers. In this paper, we consider operation principles of an energy-efficient superconductor logic and memory circuits with a short retrospective review of their evolution. We analyze their shortcomings in respect to computer circuits design. Possible ways of further research are outlined.Comment: OPEN ACCES

Josephson effect in superconductor/ferromagnet-normal/superconductor structures

The critical current IC of superconductor/ferromagnet-normal/superconductor (S/FN/S) Josephson junctions is calculated in the framework of linearized Usadel equations. The dependence of IC on the distance L between superconductors and thicknesses dF,N of ferromagnetic and normal layers is analyzed. It is shown that IC(L,dF) may exhibit damping oscillations as a function of both arguments. The conditions have been determined under which the decay length and period of oscillation of IC(L) at fixed dF are on the order of decay length of superconducting correlations in the N metal, ξN, that is much larger than in F film. We demonstrate also that the positions of the points L=Ln, at which IC=0 exhibit damping oscillations as a function of dF. The number of transitions from 0 to π states in IC(L,dF) increases under L→Ln. Outside these narrow intervals of L around Ln sign and value of IC are independent on dF for dF≳ξF. This fact is important for possible applications of S/FN/S Josephson junctions and S/FNF/S spin valve Josephson devices

Differential expression of PKD1 and PKD2 in gastric cancer and analysis of PKD1 and PKD2 function in the model system

Aim: To study the differential expression of PKD1 and PKD2 in primary gastric cancer samples and to examine the role of PKD1 and PKD2 protein kinases in regulation of gastric tumor cell biology in the model system. Methods: Tumor samples of different histological variants of primary gastric cancer were analyzed. PKD1 and PKD2 expression levels in tumor samples were accessed by Western blot analysis and quantitative polymerase chain reaction (Q-PCR). As a model system we have used gastric adenocarcinoma сell line AGS sublines constitutively transfected by pcDNA3.1 coding PKD1 or PKD2, or empty pcDNA3.1 vector. These cell lines were analyzed by Western blot, Q-PCR, MTT and proliferation assays, in vitro scratch and Transwell assays, clonogenic assay. Results: It was found that primary gastric tumors possess different levels of PKD1 and PKD2 expression on mRNA and protein levels. Low level of PKD1 expression on protein and mRNA level was detected in low differentiated adenocarcinoma and ring cell gastric cancer — disorders with poor clinical prognosis. The high level of PKD2 expression was also found in gastric tumors with poor prognosis: low differentiated adenocarcinoma and adenogen cancer. To find out whether differential expression of PKD1 and PKD2 could affect biology of gastric tumor cells in vitro, we used a model system based on AGS cell line that constitutively expressed PKD1 or overexpressed PKD2. PKD1 transfection led to the inhibition of cell proliferation, migration and colony formation, in the meanwhile, the PKD2 overexpression enhanced proliferation, migration and colony formation capacities of AGS cells. Conclusions: Our data suggest that both downregulation of PKD1 or upregulation of PKD2 expression may determine the behavior of gastric tumor cells, which promotes invasive phenotype and could result in general poor prognosis

Using digital technologies in the stock market: The criminal law aspect

Under sanctions, digital services and products that are not affected by restrictions are of particular interest to unqualified investors of the Russian stock market. The possibility of illegal use of digital technologies in the stock market has not gone unnoticed by people with criminal intent. This article analyzes the already existing illegal practices in the stock market of using digital technologies and services, and also identifies criminal legal risks of their potential development in the future. The authors use general scientific methods of research as synthesis, analysis, induction, deduction, classification, as well as special methods (systematical, structural and dogmatical, as well as content analysis methods) based on a wide range of judicial practice. As a result, the authors formulate the following main areas of using digital technologies in the stock market for criminal purposes: 1) obtaining unauthorized access to users’ personal accounts; 2) organizing the activities of financial pyramids and illegal forex dealers; 3) fraudulent activity through the marketing of financial services by illegal financial market participants; 4) using artificial intelligence for the purposes of false trading. It has been established that the measures currently taken by supervisory and law enforcement agencies are not sufficient to protect unqualified investors from the criminal actions of malefactors. At the same time, the need to strengthen control over the use of digital technologies will require finding a balance between minimizing risks by government agencies and continuing to actively use new technologies on the Russian stock market