2,030 research outputs found

    Implications of the helicity conservation for on-shell and off-shell chirality production

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    We analyze the helicity conservation following from the axial Ward identity for the massless fermion. We discuss the pair production of a fermion, \ell, and an anti-fermion, ˉ\bar{\ell}, from the annihilation process of photons, γ\gamma's and conclude that the chirality production is prohibited in any annihilation process of on-shell γ\gamma's. We demonstrate this selection rule in the tree-level process of γ+γ+ˉ\gamma+\gamma\to \ell+\bar{\ell}. We next consider the off-shell effect on the chirality production in the presence of the background magnetic field. We point out that the particle conversion process under the magnetic field induces the polarization of an incident γ\gamma, which can also be interpreted intuitively from the helicity conservation.Comment: 9 pages, 4 figure

    Processing and engineering applications of structured cellular ceramics through freezing route

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    We will report processing and engineering applications of cellular ceramics through freezing route, discussing in terms of: (1) the processing factors to create very high porosity up to 98vol% and the relationship between raw materials and slurry preparation; (2) the effect of freezing temperature and ice-binding additives on microstructures created; (3) the engineering applications of the cellular monoliths by using various starting materials, very low thermal conductivity, good electrochemical responses, dielectric and piezoelectric properties and improved strengths. In addition to that, the image based modelling techniques for mechanical properties and thermal conductivities of the resultant monoliths, based on actual microstructures collected by X-ray computed tomography, will be also studied, discussing those properties and cellular morphologies created by various freezing conditions. The simple, ecofriendly and versatile approach can modulate unique cellular architectures

    Effective restoration of chiral and axial symmetries at finite temperature and density

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    The effective restoration of chiral and axial symmetries is investigated within the framework of the SU(3) Nambu-Jona-Lasinio model. The topological susceptibility, modeled from lattice data at finite temperature, is used to extract the temperature dependence of the coupling strength of the anomaly. The study of the scalar and pseudoscalar mixing angles is performed in order to discuss the evolution of the flavor combinations of qqˉq \bar q pairs and its consequences for the degeneracy of chiral partners. A similar study at zero temperature and finite density is also realized.Comment: 5 pages, 1 figure. Talk given at Strange Quark Matter 2004, Cape Town, South Africa, 15-20 September, 200

    A novel intraperitoneal therapy for gastric cancer with DFP‐10825, a unique RNAi therapeutic targeting thymidylate synthase, in a peritoneally disseminated xenograft model

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    Purpose: In advanced gastric cancer, peritoneal dissemination is a life‐threatening mode of metastasis. Since the treatment options with conventional chemotherapy remain limited, any novel therapeutic strategy that could control such metastasis would improve the outcome of treatment. We recently developed a unique RNA interference therapeutic regimen (DFP‐10825) consisting of short hairpin RNA against thymidylate synthase (TS shRNA) and cationic liposomes. The treatment with DFP‐10825 has shown remarkable antitumor activity in peritoneally disseminated human ovarian cancer–bearing mice via intraperitoneal administration. In this study, we expanded DFP‐10825 to the treatment of peritoneally disseminated gastric cancer. Methods: DFP‐10825 was administered intraperitoneally into mice with intraperitoneally implanted human gastric cancer cells (MKN45 or NCI‐N87). Antitumor activity and host survival benefits were monitored. Intraperitoneal distribution of fluorescence‐labeled DFP‐10825 was monitored in this MKN45 peritoneally disseminated mouse model. Results: Intraperitoneal injection of DFP‐10825 suppressed tumor growth in two peritoneally disseminated cancer models (MKN45 and NCI‐N87) and increased the survival time of the MKN45 model without severe side effects. Throughout the treatment regimen, no significant body weight loss was associated with the administration of DFP‐10825. Interestingly, after intraperitoneal injection, fluorescence‐labeled DFP‐10825 retained for more than 72 hours in the peritoneal cavity and selectively accumulated in disseminated tumors. Conclusions: Intraperitoneal injection of DFP‐10825 demonstrated effective antitumor activity without systemic severe adverse effects via the selective delivery of RNAi molecules into disseminated tumors in the peritoneal cavity. Our current study indicates that DFP‐10825 could become an alternative option to improve the outcomes of patients with peritoneally disseminated gastric cancer

    Graphene-doped photo-patternable ionogels: tuning of conductivity and mechanical stability of 3D microstructures

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    This work reports for the first time the development of enhanced conductivity, graphene- doped photo-patternable hybrid organic-inorganic ionogels and the effect of the subsequent materials condensation on the conductivity and mechanical stability of three- dimensional microstructures fabricated by multi-photon polymerisation (MPP). Ionogels were based on photocurable silicon/zirconium hybrid sol-gel materials and phosphonium (trihexyltetradecylphosphonium dicyanamide [P6,6,6,14][DCA] ionic liquid (IL). To optimise the dispersion of graphene within the ionogel matrices, aqueous solutions of graphene were prepared, as opposed to the conventional graphene powder approach, and employed as catalysts of hydrolysis and condensation reactions occurring in the sol-gel process. Ionogels were prepared via a two step process by varying the hydrolysis degree from 25 to 50%, IL content between 0-50 w/w%, and the inorganic modifier (zirconate complex) concentration from 30 to 60 mol.% against the photocurable ormosil and they were characterised via Raman, Electrochemical Impedance Spectroscopy and Transmission Electron Microscopy. MPP was performed on the hybrid ionogels, resulting in three- dimensional microstructures that were characterised using scanning electron microscopy. It is clearly demonstrated that the molecular formulation of the ionogels, including the concentration of graphene and the zirconate network modifier, play a critical role in the conductivity of the ionogels and influence the resulting mechanical stability of the fabricated three-dimensional microstructures. This work aims to establish for the first time the relationship between the molecular design and condensation of materials in the physico-chemistry and dynamic of ionogels

    Families of Canonical Transformations by Hamilton-Jacobi-Poincar\'e equation. Application to Rotational and Orbital Motion

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    The Hamilton-Jacobi equation in the sense of Poincar\'e, i.e. formulated in the extended phase space and including regularization, is revisited building canonical transformations with the purpose of Hamiltonian reduction. We illustrate our approach dealing with orbital and attitude dynamics. Based on the use of Whittaker and Andoyer symplectic charts, for which all but one coordinates are cyclic in the Hamilton-Jacobi equation, we provide whole families of canonical transformations, among which one recognizes the familiar ones used in orbital and attitude dynamics. In addition, new canonical transformations are demonstrated.Comment: 21 page
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