78 research outputs found

    Decision Support System For Safety Warning Of Bridge – A Case Study In Central Taiwan

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    This study aims at developing the decision support system (DSS) for safety warning of bridge. In the DSS, real-time and forecasted radar rainfalls are used to predict flood stage, velocity and scouring depth around bridge piers for one to three hours ahead. The techniques adopted in the DSS include (1) measurement and correction models of radar rainfall, (2) a grid-based distributed rainfall-runoff model for simulating reservoir inflows, (3) models for predicting flood stages, velocities and scouring depths around bridge piers, and (4) ultimate analysis approaches for evaluating safety of pier foundation. The DSS can support the management department to decide whether they should close bridges or not during floods. The proposed DSS gave a test-run during Typhoon Morakot in 2009 in Dajia River Basin, central Taiwan. The results show the DSS has reasonable performances during floods

    Effects of Domain Selection on Singular-Value-Decomposition Based Statistical Downscaling of Monthly Rainfall Accumulation in Southern Taiwan

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    A singular-value-decomposition (SVD) statistical downscaling technique was developed for monthly rainfall over southern Taiwan. The statistical model was applied to seven different general circulation models. Seven different geographical domains for the large-scale atmospheric predictors were tested and their effects on rainfall projections were evaluated. Because different climate models indicate different future rainfall projections, a multi-model ensemble approach was applied to provide best guess estimates. Using the multi-model ensemble, and a range of metrics, it was found that the different predictor geographical domains had little influence on the projected monthly rainfalls. Two emission climate change scenarios (A1B and B1) were used to project the future rainfalls for the period from 2010 to 2045 across southern Taiwan. Overall, future rainfall shows an increasing trend during the May-to-October wet season and a decreasing trend during the November-to-April dry season

    Sap Flow Sensors: Construction, Quality Control and Comparison

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    This work provides a design for two types of sensors, based on the thermal dissipation and heat ratio methods of sap flow calculation, for moderate to large scale deployments for the purpose of monitoring tree transpiration. These designs include a procedure for making these sensors, a quality control method for the final products, and a complete list of components with vendors and pricing information. Both sensor designs were field tested alongside a commercial sap flow sensor to assess their performance and show the importance for quality controlling the sensor outputs. Results show that for roughly 2% of the cost of commercial sensors, self-made sap flow sensors can provide acceptable estimates of the sap flow measurements compared to the commercial sensors

    New provincial CO2 emission inventories in China based on apparent energy consumption data and updated emission factors

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    This study employs “apparent energy consumption” approach and updated emissions factors to re-calculate Chinese provincial CO2 emissions during 2000–2012 to reduce the uncertainty in Chinese CO2 emission estimates for the first time. The study presents the changing emission-socioeconomic features of each provinces as well. The results indicate that Chinese provincial aggregated CO2 emissions calculated by the apparent energy consumption and updated emissions factors are coincident with the national emissions estimated by the same approach, which are 12.69% smaller than the one calculated by the traditional approach and IPCC default emission factors. The provincial aggregated CO2 emissions increased from 3160 million tonnes in 2000 to 8583 million tonnes in 2012. During the period, Shandong province contributed most to national emissions accumulatively (with an average percentage of 10.35%), followed by Liaoning (6.69%), Hebei (6.69%) and Shanxi provinces (6.25%). Most of the CO2 emissions were from raw coal, which is primarily burned in the thermal power sector. The analyses of per capita emissions and emission intensity in 2012 indicates that provinces located in the northwest and north had higher per capita CO2 emissions and emission intensities than the central and southeast coastal regions. Understanding the emissions and emission-socioeconomic characteristics of different provinces is critical for developing mitigation strategies

    Toward controllable and predictable synthesis of high-entropy alloy nanocrystals.

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    High-entropy alloy (HEA) nanocrystals have attracted extensive attention in catalysis. However, there are no effective strategies for synthesizing them in a controllable and predictable manner. With quinary HEA nanocrystals made of platinum-group metals as an example, we demonstrate that their structures with spatial compositions can be predicted by quantitatively knowing the reduction kinetics of metal precursors and entropy of mixing in the nanocrystals under dropwise addition of the mixing five-metal precursor solution. The time to reach a steady state for each precursor plays a pivotal role in determining the structures of HEA nanocrystals with homogeneous alloy and core-shell features. Compared to the commercial platinum/carbon and phase-separated counterparts, the dendritic HEA nanocrystals with a defect-rich surface show substantial enhancement in catalytic activity and durability toward both hydrogen evolution and oxidation. This quantitative study will lead to a paradigm shift in the design of HEA nanocrystals, pushing away from the trial-and-error approach

    Systems Biology Modeling Reveals a Possible Mechanism of the Tumor Cell Death upon Oncogene Inactivation in EGFR Addicted Cancers

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    Despite many evidences supporting the concept of “oncogene addiction” and many hypotheses rationalizing it, there is still a lack of detailed understanding to the precise molecular mechanism underlying oncogene addiction. In this account, we developed a mathematic model of epidermal growth factor receptor (EGFR) associated signaling network, which involves EGFR-driving proliferation/pro-survival signaling pathways Ras/extracellular-signal-regulated kinase (ERK) and phosphoinositol-3 kinase (PI3K)/AKT, and pro-apoptotic signaling pathway apoptosis signal-regulating kinase 1 (ASK1)/p38. In the setting of sustained EGFR activation, the simulation results show a persistent high level of proliferation/pro-survival effectors phospho-ERK and phospho-AKT, and a basal level of pro-apoptotic effector phospho-p38. The potential of p38 activation (apoptotic potential) due to the elevated level of reactive oxygen species (ROS) is largely suppressed by the negative crosstalk between PI3K/AKT and ASK1/p38 pathways. Upon acute EGFR inactivation, the survival signals decay rapidly, followed by a fast increase of the apoptotic signal due to the release of apoptotic potential. Overall, our systems biology modeling together with experimental validations reveals that inhibition of survival signals and concomitant release of apoptotic potential jointly contribute to the tumor cell death following the inhibition of addicted oncogene in EGFR addicted cancers
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